1,171 research outputs found
Commuter aircraft aerodynamic design: wind-tunnel tests and CFD analysis
The paper presents wind-tunnel tests and CFD numerical aerodynamic analysis of Tecnam P2012 Traveller aircraft. An extensive wind tunnel tests campaign of several different modular aircraft configurations analyzed has been performed on a scaled model in order to experimentally estimate both longitudinal and lateral-directional stability, control derivatives, and to improve the aircraft aerodynamic performances. Simultaneously numerical investigations through a CFD software has been performed, both at wind-tunnel tests Reynolds number (Re=0.6millions) and at free flight Reynolds number of the full scale aircraft (Re=4 or 9 millions). Finally results are compared showing a good agreement in the lift and pitching moment coefficient both with and without control surfaces or flap deflections, and an underestimation of drag coefficient in the CFD numerical analysis. Horizontal tail positions are also tested in wind-tunnel and compared to CFD analysis highlighting how an accurate design leads to improvement both in stability and control. Results will be very useful in the final design of the aircraft and to perform dynamic simulations
Novel Cephalosporins in Septic Subjects and Severe Infections: Present Findings and Future Perspective
Production and characterization of polyethylene terephthalate nanoparticles
Microplastic (MP) pollution represents one of the biggest environmental problems that is further exacerbated by the continuous degradation in the marine environment of MPs to nanoplastics (NPs). The most diffuse plastics in oceans are commodity polymers, mainly thermoplastics widely used for packaging, such as polyethylene terephthalate (PET). However, the huge interest in the chemical vector role of micro/nanoplastics, their fate and negative effects on the environment and human health is still under discussion and the research is still sparse due also to the difficulties of sampling MPs and NPs from the environment or producing NPs in laboratory. Moreover, the research on MPs and NPs pollution relies on the availability of engineered nanoparticles similar to those present in the marine environment for toxicological, transport and adsorption studies in biological tissues as well as for wastewater remediation studies. This work aims to develop an easy, fast and scalable procedure for the production of representative model nanoplastics from PET pellets. The proposed method, based on a simple and economic milling process, has been optimized considering the peculiarities of the polymer. The results demonstrated the reliability of the method for preparing particle suspensions for aquatic microplastic research, with evident advantages compared to the present literature procedures, such as low cost, the absence of liquid nitrogen, the short production time, the high yield of the process, stability, reproducibility and polydisperse size distribution of the produced water dispersed nanometric PET
The challenge of perioperative pain management in opioid-tolerant patients
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals. Anesthesiologists, surgeons, and nurses should be familiar with some pharmacological phenomena which are typical of opioid users and abusers, such as tolerance, physical dependence, hyperalgesia, and addiction. Inadequate pain management is very common in these patients, due to common prejudices and fears. The target of preoperative evaluation is to identify comorbidities and risk factors and recognize signs and symptoms of opioid abuse and opioid withdrawal. Clinicians are encouraged to plan perioperative pain medications and to refer these patients to psychiatrists and addiction specialists for their evaluation. The aim of this review was to give practical suggestions for perioperative management of surgical opioid-tolerant patients, together with schemes of opioid conversion for chronic pain patients assuming oral or transdermal opioids, and patients under maintenance programs with methadone, buprenorphine, or naltrexone
Fused Filament Fabrication and Computer Numerical Control Milling in Cultural Heritage Conservation
This paper reports a comparison between the advantages and disadvantages of fused filament fabrication (FFF) and computer numerical control (CNC) milling, when applied to a specific case of conservation of cultural heritage: the reproduction of four missing columns of a 17th-century tabernacle. To make the replica prototypes, European pine wood (the original material) was used for CNC milling, while polyethylene terephthalate glycol (PETG) was used for FFF printing. Neat materials were chemically and structurally characterized (FTIR, XRD, DSC, contact angle measurement, colorimetry, and bending tests) before and after artificial aging, in order to study their durability. The comparison showed that although both materials are subject to a decrease in crystallinity (an increase in amorphous bands in XRD diffractograms) and mechanical performance with aging, these characteristics are less evident in PETG (E = 1.13 +/- 0.01 GPa and sigma = 60.20 +/- 2.11 MPa after aging), which retains water repellent (ca = 95.96 +/- 5.56 degrees) and colorimetric ( increment E = 2.6) properties. Furthermore, the increase in flexural strain (%) in pine wood, from 3.71 +/- 0.03% to 4.11 +/- 0.02%, makes it not suitable for purpose. Both techniques were then used to produce the same column, showing that for this specific application CNC milling is quicker than FFF, but, at the same time, it is also much more expensive and produces a huge amount of waste material compared to FFF printing. Based on these results, it was assessed that FFF is more suitable for the replication of the specific column. For this reason, only the 3D-printed PETG column was used for the subsequent conservative restoration
Design and optimization of a large turboprop aircraft
This paper proposes a feasibility study concerning a large turboprop aircraft to be used as a lower environmental impact solution to current regional jets operated on short/medium hauls. An overview of this market scenario highlights that this segment is evenly shared between regional turboprop and jet aircraft. Although regional jets ensure a large operative flexibility, they are usually not optimized for short missions with a negative effect on block fuel and environmental impact. Conversely, turboprops represent a greener solution but with reduced passenger capacity and speed. Those aspects highlight a slot for a new turboprop platform coupling higher seat capacity, cruise speed and design range with a reduced fuel consumption. This platform should operate on those ranges where neither jet aircraft nor existing turboprops are optimized. This work compares three different solutions: a highâwing layout with underâwing engines installation and both two-and threeâliftingâsurface configurations with lowâwing and tail tipsâmounted engines. For each concept, a multiâdisciplinary optimization was performed targeting the minimum block fuel on a 1600 NM mission. Optimum solutions were compared with both a regional jet such as the Airbus A220â300 operated on 1600 NM and with a jet aircraft specifically designed for this range
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