2,651 research outputs found
The regulation of Escherichia coli methylglyoxal synthase; a new control site in glycolysis?
The stratigraphy, correlation, provenance and palaeogeography of the Skiddaw Group (Ordovician) in the English Lake District
A new lithostratigraphy is presented for the Skiddaw Group (lower Ordovician) of the English Lake District. Two stratigraphical belts are described. Five formations are defined in the Northern Fells Belt, ranging in age from Tremadoc to early Llanvirn. They are all mudstone or sandstone dominated, of turbidite origin; in ascending order they are named the Bitter Beck, Watch Hill, Hope Beck, Loweswater and Kirk Stile formations. Two formations are defined in the Central Fells Belt, ranging in age from late Arenig to Llanvirn. These are the Buttermere Formation - a major olistostrome deposit - overlain by the Tarn Moor Formation, consisting of turbidite mudstones with volcaniclastic turbidite sandstone beds. A revised graptolite and new acritarch biostratigraphy for the Skiddaw Group is presented with eight graptolite biozones and thirteen acritarch assemblages and sub-assemblages. The provenance of the group is assessed from detailed petrographical and geochemical work. This suggests derivation, in the early Ordovician, largely from an old inactive continental arc terrane lying to the south-east, with the appearance of juvenile volcanic material in the Llanvirn. Comparisons and correlations of the Skiddaw Group are made with the Isle of Man and eastern Ireland
Linking anthropogenic resources to wildlife-pathogen dynamics: a review and meta-analysis
Urbanisation and agriculture cause declines for many wildlife, but some species benefit from novelresources, especially food, provided in human-dominated habitats. Resulting shifts in wildlife ecol-ogy can alter infectious disease dynamics and create opportunities for cross-species transmission,yet predicting host–pathogen responses to resource provisioning is challenging. Factors enhancingtransmission, such as increased aggregation, could be offset by better host immunity due toimproved nutrition. Here, we conduct a review and meta-analysis to show that food provisioningresults in highly heterogeneous infection outcomes that depend on pathogen type and anthropo-genic food source. We also find empirical support for behavioural and immune mechanismsthrough which human-provided resources alter host exposure and tolerance to pathogens. Areview of recent theoretical models of resource provisioning and infection dynamics shows thatchanges in host contact rates and immunity produce strong non-linear responses in pathogen inva-sion and prevalence. By integrating results of our meta-analysis back into a theoretical frame-work, we find provisioning amplifies pathogen invasion under increased host aggregation andtolerance, but reduces transmission if provisioned food decreases dietary exposure to parasites.These results carry implications for wildlife disease management and highlight areas for futurework, such as how resource shifts might affect virulence evolution
Structural and electrical properties of c-axis oriented Y1-xCaxBa2(Cu1-yZny)3O7-delta thin films grown by pulsed laser deposition
Ca- and Zn-subsituted Y1-xCaxBa2(Cu1-yZny)O7-delta (x = 0, 0.05 and y = 0,
0.02, 0.04, 0.05) thin films were grown on SrTiO3 (100) substrates using the
pulsed laser deposition (PLD) technique. Effects of various growth parameters
on the quality of the film were studied via X-ray diffraction (XRD), atomic
force microscopy (AFM), and in-plane resistivity, rhoab(T), measurements. The
deposition temperature and oxygen partial pressure were gradually increased to
820C and 1.20 mbar respectively. Films grown under these conditions exhibited
good c-axis orientation (primarily limited by the grain size) and low values of
the extrapolated residual resistivity, rho(0), at zero temperature. The planar
hole content, p, was determined from the room temperature thermopower, S[290K],
measurements and the effects of oxygen annealing were also studied. Fully
oxygenated samples were found to be overdoped with p ~ 0.195. The
Superconducting transition temperature Tc(p), and rho(T,p) showed the expected
systematic variations with changing Zn content.Comment: Submitted to Physica C (2003
On Exactness Of The Supersymmetric WKB Approximation Scheme
Exactness of the lowest order supersymmetric WKB (SWKB) quantization
condition , for certain
potentials, is examined, using complex integration technique. Comparison of the
above scheme with a similar, but {\it exact} quantization condition, , originating from the quantum Hamilton-Jacobi
formalism reveals that, the locations and the residues of the poles that
contribute to these integrals match identically, for both of these cases. As
these poles completely determine the eigenvalues in these two cases, the
exactness of the SWKB for these potentials is accounted for. Three non-exact
cases are also analysed; the origin of this non-exactness is shown to be due
the presence of additional singularities in , like branch
cuts in the plane.Comment: 11 pages, latex, 1 figure available on reques
Carbon sequestration and biogeochemical cycling in a saltmarsh subject to coastal managed realignment
Globally, wetlands provide the largest terrestrial carbon (C) store, and restoration of degraded wetlands provides a potentially important mechanism for climate change mitigation. We examined the potential for restored saltmarshes to sequester carbon, and found that they can provide a modest, but sustained, sink for atmospheric CO2. Rates of C and nutrient cycling were measured and compared between a natural saltmarsh (high- and low-shore locations), claimed arable land on former high-shore saltmarsh and a managed realignment restoration site (high- and low-shore) in transition from agricultural land to saltmarsh 15 years after realignment, at Tollesbury, Essex, UK. We measured pools and turnover of C and nitrogen (N) in soil and vegetation at each site using a range of methods, including gas flux measurement and isotopic labelling. The natural high-shore site had the highest soil organic matter concentrations, topsoil C stock and below-ground biomass, whereas the agricultural site had the highest total extractable N concentration and lowest soil C/N ratio. Ecosystem respiration rates were similar across all three high-shore sites, but much higher in both low-shore sites, which receive regular inputs of organic matter and nutrients from the estuary. Total evolution of 14C-isotopically labelled substrate as CO2 was highest at the agricultural site, suggesting that low observed respiration rates here were due to low substrate supply (following a recent harvest) rather than to inherently low microbial activity. The results suggest that, after 15 years, the managed realignment site is not fully equivalent to the natural saltmarsh in terms of biological and chemical function. While above ground biomass, extractable N and substrate mineralisation rates in the high-shore site were all quite similar to the natural site, less dynamic ecosystem properties including soil C stock, C/N ratio and below-ground biomass all remained more similar to the agricultural site. These results suggest that reversion to natural biogeochemical functioning will occur following restoration, but is likely to be slow; we estimate that it will take approximately 100 years for the restored site to accumulate the amount of C currently stored in the natural site, at a rate of 0.92 t C ha−1 yr−1
Social Conformity in Autism
Humans are extremely susceptible to social influence. Here, we examine whether this susceptibility is altered in autism, a condition characterized by social difficulties. Autistic participants (N=22) and neurotypical controls (N=22) completed a memory test of previously seen words and were then exposed to answers supposedly given by four other individuals. Autistic individuals and controls were as likely to alter their judgements to align with inaccurate responses of group members. These changes reflected both temporary judgement changes (public conformity) and long-lasting memory changes (private conformity). Both groups were more susceptible to answers believed to be from other humans than from computer algorithms. Our results suggest that autistic individuals and controls are equally susceptible to social influence when reporting their memories
Evaluating the Acoustic Effect of Over-the-Rotor Foam-Metal Liner Installed on a Low Speed Fan Using Virtual Rotating Microphone Imaging
An in-duct beamforming technique for imaging rotating broadband fan sources has been used to evaluate the acoustic characteristics of a Foam-Metal Liner installed over-the-rotor of a low-speed fan. The NASA Glenn Research Center s Advanced Noise Control Fan was used as a test bed. A duct wall-mounted phased array consisting of several rings of microphones was employed. The data are mathematically resampled in the fan rotating reference frame and subsequently used in a conventional beamforming technique. The steering vectors for the beamforming technique are derived from annular duct modes, so that effects of reflections from the duct walls are reduced
Isolating viable ancient bacteria: what you put in is what you get out
Letter to the editorRaphael Eisenhofer, Alan Cooper, Laura S. Weyric
- …