Examining the Effects of Menstrual Cycle Phase and Hormonal Contraceptive Use on Women\u27s Sleep

Women overrepresent men for sub-optimal sleep, a consequence of hormone fluctuation in the menstrual cycle affecting sleep regulatory pathways. While research has examined the prevalence of sub-optimal sleep through cycle phases, little research has examined how hormonal contraceptives (HC’s) could similarly affect women’s sleep, while also neglecting to utilize subjective sleep measures. In this study, we examine subjective sleep quality among naturally cycling (NC) women, women using different HC types, and between active and inactive phase pill users by subjecting 463 women to a subjective sleep battery. We hypothesized that HC users would report more sub-optimal sleep than NC women. Our study yielded non-significant total findings between sleep and HC/NC women, but marginally significant trends between individual HC types and active versus inactive pill phases. These findings suggest a more nuanced relationship between hormones and sleep, motivating future research to further delineate this relationship to improve women’s sleep-health outcomes

Examining the Effects of Menstrual Cycle Phase and Hormonal Contraceptive Use on Women\u27s Sleep

Women overrepresent men for sub-optimal sleep, a consequence of hormone fluctuation in the menstrual cycle affecting sleep regulatory pathways. While research has examined the prevalence of sub-optimal sleep through cycle phases, little research has examined how hormonal contraceptives (HC’s) could similarly affect women’s sleep, while also neglecting to utilize subjective sleep measures. In this study, we examine subjective sleep quality among naturally cycling (NC) women, women using different HC types, and between active and inactive phase pill users by subjecting 463 women to a subjective sleep battery. We hypothesized that HC users would report more sub-optimal sleep than NC women. Our study yielded non-significant total findings between sleep and HC/NC women, but marginally significant trends between individual HC types and active versus inactive pill phases. These findings suggest a more nuanced relationship between hormones and sleep, motivating future research to further delineate this relationship to improve women’s sleep-health outcomes

Concert recording 2021-10-28

[Track 1]. À la manière de Schumann / Jean-Michel Defaye -- [Track 2]. Bushes and briars / Ralph Vaughan Williams ; arranged by Richard Myers-- [Track 3]. Now is the month of Maying / Thomas Morley-- [Track 4]. Concerto in one movement / Alexey Lebedev -- [Track 5]. Suite of Lieder. I. Lob der Einsamkeit ; II. Grab und Mond ; III. Widersprich / Franz Schubert ; arranged by Rowell -- [Track 6]. The song of King David / Norman Bolter -- [Track 7]. Leviathan / Jack Wilds -- [Track 8]. -- Ave Maria / Anton Bruckner ; arranged by Donald R. Frederick -- [Track 9]. Prelude, op. 34, no. 19. / Dimitri Shostakovich-- [Track 10]. A canzona concoction / Allen Molineux

Concert recording 2021-11-07a

[Track 1]. La maniere de Shumann /Jean-Michel Defaye -- [Track 2]. Sang till lotta / Jan Sandstrom -- [Track 3]. Concertino in B♭ / Ernst Sachse -- [Track 4]. Nearer my God to thee for 9 celli / James Stevens -- [Track 5]. Ave Maria / Franz Biebl -- [Track 6]. Soundtrack for trombone / Brian Sadler

Concert recording 2019-10-23

[Track 1]. Morgenmusik. I. Massig bewegt [Track 2]. II. Langsame viertel [Track 3]. III. Bewegt / Paul Hindemith -- [Track 4]. Joshua fit de Battle of Jericho / traditional, arranged by Chris Woods -- [Track 5]. Fantasy for trombone / Elizabeth Raum -- [Track 6]. Suite. I. Passepied [Track 7]. II. Arietta [Track 8]. III. March / Johann Adolphe Hesse, ed. William Glover -- [Track 9]. Suite for four trombones. I. Poco maestoso [Track 10]. II. Sarabanda [Track 11]. III. Alla marcia [Track 12]. IV. Spirituale [Track 13]. V. Finale alla fuga / Gordon Jacob -- [Track 14]. Concertino. II. Aria: Andante sostenuto [Track 15]. III. Finale: Allegro giocoso / Lars-Erik Larsson -- [Track 16]. Andante et allegro / Joseph Edouard Barat -- [Track 17]. Horizon of the Aten / Anthony Barfield -- [Track 18]. Round midnight / Thelonious Monk, arranged by Slide Hampton

Defense contingency contracting handbook, Essential tools, information, and training to meet contingency contracting needs for the 21st century

This handbook provides a pocket-sized guide to help you meet the needs of those whom you are supporting. This is crucial to your success and that of the overall mission. It is by no means a stand-alone document and must be read together with the Federal Acquisition Regulation, the Defense Federal Acquisition Regulation Supplement, and Operational Contract Support in Joint Operations (Joint Publication 4-10)

Travel-associated lineages and unique endemic antimicrobial-susceptible lineages of Neisseria gonorrhoeae predominate in Western Australia

In Australia, gonococcal isolates are monitored for antimicrobial susceptibilities. In Western Australia (WA), gonorrhoea notification rates increased by 63 % between 2013 and 2016, with the steepest increase occurring between 2015 and 2016, before stabilizing at this higher baseline between 2017 and 2020. This increased prevalence was associated with antimicrobial-susceptible (AMS) lineages. To understand the provenance of these isolates causing gonorrhoea in WA, whether they were introduced or expanded from endogenous lineages, 741 isolates were collected in 2017 and characterized by both iPLEX typing and whole genome sequencing (WGS). Antibiograms and genocoding of the isolates revealed that AMS isolates were most prevalent in the remote regions, while the urban/rural regions were characterized by antimicrobial-resistant (AMR) isolates. iPLEX typing identified 78 iPLEX genotypes (WA-1 to WA-78) of which 20 accounted for over 88 % of isolates. WA-10 was the most frequently identified genotype in the urban/rural regions whilst WA-29 was the most frequently identified genotype in the remote regions. Genotypes WA-38, WA-52 and WA-13 accounted for 81 % (n=36/44) of the azithromycin-resistant N. gonorrhoeae (AziR) isolates. A representative isolate of each iPLEX genotype and AMR biotype was whole genome sequenced and analysed using MLST, NG-MAST and NG-STAR, and the novel core genome clustering Ng_cgc_400 typing scheme. Five predominant Bayesian population groups (termed BPG-1 to 5) were identified in the study collection. BPG-1 and BPG-2 were associated with AMS isolates from the remote regions. BPG-1 and BPG-2 were shown to be unique to the remote regions based on a minimum spanning tree against 4000 international isolates. AMS isolates in urban/rural regions were dominated by international lineages. AziR and Cef DS (decreased susceptibility to ceftriaxone) was concentrated in three urban/rural genomic groups (BPG-3, 4 and 5). Azithromycin minimum inhibitory concentrations (0.5–16 mg l−1) correlated with the accumulation of mtrR mutations or/and the fraction of 23S rRNA C2611T mutated copies. The majority of isolates in BPG-3, 4 and 5 could be correlated with known AMR lineages circulating globally and nationally. In conclusion, the surge in AMS isolates in WA in 2017 was due to importation of international AMS lineages into urban/rural regions, whilst the local AMS lineages persisted largely in the remote regions. Bridging between the urban/rural and remote regions was relatively rare, but continued surveillance is required to prevent ingress of AMR strains/lineages into the remote regions of WA

Marijuana Use Among Young Black Men Who Have Sex With Men and the HIV Care Continuum: Findings From the uConnect Cohort

<p><i>Background:</i> Young Black men who have sex with men (YBMSM) are at highest risk for HIV seroconversion in the United States. Successful movement through the HIV care continuum is an important intervention for limiting onwards HIV transmission. <i>Objective:</i> Little data exists on how substances most commonly used by YBMSM, such as marijuana, are related to the HIV continuum, which represents the primary aim of this study. <i>Methods:</i> A cohort of YBMSM (<i>n</i> = 618) was generated through respondent-driven sampling. Frequency of marijuana use and marijuana use as a sex-drug were assessed across the HIV care continuum using weighted logistic regression models. <i>Results:</i> Study participants reported more intermittent marijuana use (<i>n</i> = 254, 56.2%) compared to heavy use (<i>n</i> = 198, 43.8%). Our sample contained 212 (34.3%) HIV seropositive participants of which 52 (24.5%) were unaware of their HIV positive status. Study participants who were heavy marijuana users were more likely to be unaware of their HIV seropositive status (AOR: 4.18; 95% CI 1.26, 13.89). All other stages in the care continuum demonstrated no significant differences between those who use marijuana intermittently or heavily or as a sex-drug and nonusers. <i>Conclusions:</i> YBMSM who used marijuana heavily were more likely to be HIV-positive unaware than those who never used marijuana. Findings were inconclusive regarding the relationships between marijuana use and other HIV care continuum metrics. However, knowledge of ones’ HIV status is a critical requirement for engaging in care and may have implications for onwards HIV transmission.</p