Delta Air Lines and Its Future

A synopsis of current hiring at Delta and what the airline is looking for in candidates

Standardized Testing: A Case Study of Preparation for College & Work?

The following is a case study one Illinois high school’s test results using the EXPLORE® and PLAN® tests in correlation with the students’ academic history. Juniors were administered the PLAN test in tenth grade and three years of academic history were reviewed. Seniors were administered the EXPLORE test in ninth grade, the PLAN test in tenth grade, and two years of academic history were reviewed. The results of this case study analysis have lead to recommendations regarding curriculum and its correlation to these specific standardized tests

Standardized Testing: A Case Study of Preparation for College & Work?

The following is a case study one Illinois high school’s test results using the EXPLORE® and PLAN® tests in correlation with the students’ academic history. Juniors were administered the PLAN test in tenth grade and three years of academic history were reviewed. Seniors were administered the EXPLORE test in ninth grade, the PLAN test in tenth grade, and two years of academic history were reviewed. The results of this case study analysis have lead to recommendations regarding curriculum and its correlation to these specific standardized tests

Foremost Watchman: Ideological Consistency and Sociopolitical Change in Emerson's Antislavery Addresses

The most common critical perceptions concerning the career of Ralph Waldo Emerson have tended to emphasize the strength and originality of his earliest, and seemingly most influential, works. Nature, published in 1836, and the compositions contained in Essays, First Series and Essays, Second Series, published in 1841 and] 844 respectively, provide the foundation upon which Emerson's transcendental philosophy is erected: Emerson hereby introduces a uniquely American agenda that espouses original and independent notions with regard to the individual, his role in society, and the fundamental need for self-determination. Nature, "History," "Circles," "The Poet," "Experience," and "Self-Reliance," as well as the texts of "The American Scholar." "Man the Reformer," and other seminal works are readily found in any good volume of Selected Essays, a condition which understandably serves to reinforce inherited assumptions that Emerson's was a life and career which was, as Larzer Ziff contends, "punctuated by the excitement of ideas rather than events

Implementation of An Immediate Postpartum Long-Acting Reversible Contraception Program in a Southern Texas Border Population

Background: Expanding contraceptive access in a Southern Texas border population can reduce the number of unintended and short-interval pregnancies, which have been associated with poor maternal and neonatal health outcomes. Healthcare encounters can be maximized to include immediate postpartum long-acting reversible contraception (IPP LARC) as an additive to the healthcare access many women have during pregnancy. The implementation of the IPP LARC Program allowed for the provision of accessible LARCs to fulfill the contraceptive needs of our patient population. This program was supported by Medicaid reimbursements and a private teaching grant that was awarded to the University of Texas Rio Grande Valley (UTRGV) Ob/Gyn residency program at Doctors Hospital at Renaissance (DHR). Methods: Data was collected retrospectively from participants who received a LARC from 2/2017 to 7/2021 at DHR Women’s Hospital after receiving IRB approval. Patient demographic information, such as age, gravidity, parity, delivery route, primary provider, and funding were assessed, along with LARC distribution and insertion timing. The reimbursement status for Medicaid-funded devices was obtained from the DHR Billing Department. Results: A total of 467 LARCs were inserted under the IPP LARC Program over 4.5 years. Ages ranged from 13-57 years old. A total of 353 (76%) participants received primary care from the UTRGV Ob/Gyn Residency Program. All others were consults who had received care from private physicians at the DHR WH. A total of 314 (67.2%) implants and 153 (32.8%) IUDs were inserted and 313 (75%) devices were placed following a vaginal delivery, while 103 (25%) after a cesarean section. Majority (257 participants (55.2%)) lacked funding, while 193 (41.4%) had Medicaid, and 16 (3.4%) had private insurance. Conclusion: The IPP LARC program provided for 467 participants, with majority of the recipients requesting immediate postpartum contraception. Most lacked adequate funding and many requests came from private providers wanting to provide patients with their desired postpartum contraceptive method. The program helped fulfill the contraceptive needs of this population by expanding access regardless of funding status. Follow-up studies should assess patient satisfaction and LARC continuation rates to help obtain future funding and promote expansion of the program

A Conversation About Current Issues Facing the Global Financial Industry

https://digitalcommons.nyls.edu/filler_institute_events/1014/thumbnail.jp

Similarities and differences in circuit responses to applied Gly \u3csup\u3e1\u3c/sup\u3e -SIFamide and peptidergic (Gly \u3csup\u3e1\u3c/sup\u3e -SIFamide) neuron stimulation

Similarities and differences in circuit responses to applied Gly 1 -SIFamide and peptidergic (Gly 1 -SIFamide) neuron stimulation. J Neurophysiol 121: 950 –972, 2019. First published January 16, 2019; doi:10.1152/jn.00567.2018.—Microcircuit modulation by peptides is well established, but the cellular/synaptic mechanisms whereby identified neurons with identified peptide transmitters modulate microcircuits remain unknown for most systems. Here, we describe the distribution of GYRKPPFNGSIFamide (Gly 1 -SIFamide) immunoreactivity (Gly 1 -SIFamide-IR) in the stomatogastric nervous system (STNS) of the crab Cancer borealis and the Gly 1 -SIFamide actions on the two feeding-related circuits in the stomatogastric ganglion (STG). Gly 1 -SIFamide-IR localized to somata in the paired commissural ganglia (CoGs), two axons in the nerves connecting each CoG with the STG, and the CoG and STG neuropil. We identified one Gly 1 -SIFamide-IR projection neuron innervating the STG as the previously identified modulatory commissural neuron 5 (MCN5). Brief (~10 s) MCN5 stimulation excites some pyloric circuit neurons. We now find that bath applying Gly 1 -SIFamide to the isolated STG also enhanced pyloric rhythm activity and activated an imperfectly coordinated gastric mill rhythm that included unusually prolonged bursts in two circuit neurons [inferior cardiac (IC), lateral posterior gastric (LPG)]. Furthermore, longer duration (±30 s) MCN5 stimulation activated a Gly 1 -SIFamide-like gastric mill rhythm, including prolonged IC and LPG bursting. The prolonged LPG bursting decreased the coincidence of its activity with neurons to which it is electrically coupled. We also identified local circuit feedback onto the MCN5 axon terminals, which may contribute to some distinctions between the responses to MCN5 stimulation and Gly 1 -SIFamide application. Thus, MCN5 adds to the few identified projection neurons that modulate a well-defined circuit at least partly via an identified neuropeptide transmitter and provides an opportunity to study peptide regulation of electrical coupled neurons in a functional context. NEW & NOTEWORTHY Limited insight exists regarding how identified peptidergic neurons modulate microcircuits. We show that the modulatory projection neuron modulatory commissural neuron 5 (MCN5) is peptidergic, containing Gly 1 -SIFamide. MCN5 and Gly 1 -SIFamide elicit similar output from two well-defined motor circuits. Their distinct actions may result partly from circuit feedback onto the MCN5 axon terminals. Their similar actions include eliciting divergent activity patterns in normally coactive, electrically coupled neurons, providing an opportunity to examine peptide modulation of electrically coupled neurons in a functional context

A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1.

Testis-expressed X-linked genes typically evolve rapidly. Here, we report on a testis-expressed X-linked microRNA (miRNA) cluster that despite rapid alterations in sequence has retained its position in the Fragile-X region of the X chromosome in placental mammals. Surprisingly, the miRNAs encoded by this cluster (Fx-mir) have a predilection for targeting the immediately adjacent gene, Fmr1, an unexpected finding given that miRNAs usually act in trans, not in cis Robust repression of Fmr1 is conferred by combinations of Fx-mir miRNAs induced in Sertoli cells (SCs) during postnatal development when they terminate proliferation. Physiological significance is suggested by the finding that FMRP, the protein product of Fmr1, is downregulated when Fx-mir miRNAs are induced, and that FMRP loss causes SC hyperproliferation and spermatogenic defects. Fx-mir miRNAs not only regulate the expression of FMRP, but also regulate the expression of eIF4E and CYFIP1, which together with FMRP form a translational regulatory complex. Our results support a model in which Fx-mir family members act cooperatively to regulate the translation of batteries of mRNAs in a developmentally regulated manner in SCs

Quantitative and qualitative analysis of individual experiences post botulinum toxin injection ‐ United Kingdom Survey

Introduction In the United Kingdom (UK), complications that arise following the administration of Botulinum Toxin are reported to the Medicines and Health Regulatory Agency (MHRA) via the Yellow Card Reporting Scheme. Over the past decade, there has been a significant increase in the number of non-surgical aesthetic procedures. Concerns have been raised that the MHRA is not fully capturing complications in terms of volume and impact on patients. Aim This novel study explores the lived experiences of individuals who have experienced an adverse event following administration of Botulinum Toxin for aesthetic purposes. Using a combination of qualitative and quantitative methodologies, this analysis evaluates data relating to long-lasting physical, psychological, emotional, and financial sequelae of complications arising from cosmetic Botulinum Toxin injections in the UK. Methods A mixed method, qualitative and quantitative approach was adopted to gain comprehensive insights into patients' experiences. A focus group which comprised patient representatives, psychologists, and researchers reached a consensus on a 17-question survey which was disseminated via social media channels. Deductive thematic analysis was used to analyse coded themes. Furthermore, for secondary analysis, sentiment analysis was used computationally as an innovative approach to identify and categorise free text responses associated with sentiments using natural language processing (NLP). Results In the study, 655 responses were received, with 287 (44%) of respondents completing all questions. The mean age of respondents was 42.6 years old. 94.1% of respondents identified as female. In the sample, 79% of respondents reported an adverse event following their procedure, with the most common event being reported as ‘anxiety’. Findings revealed that 69% of respondents reported long-lasting adverse effects. From the responses, 68.4% reported not having recovered physically, 63.5% of respondents stated that they had not recovered emotionally from complications, and 61.7% said that they have not recovered psychologically. In addition, 84% of respondents stated that they do not know who regulates the aesthetics industry. Furthermore, 92% of participants reported that their clinic or practitioner did not inform them about the Yellow Card Reporting Scheme. The sentiment analysis using the AFINN Lexicon yielded adjusted scores ranging from −3 to +2, with a mean value of −1.58. Conclusion This is the largest survey in the UK completed by patients who experienced an adverse outcome following the aesthetic administration of Botulinum Toxin. Our study highlights the extent of the challenges faced by patients who experience an adverse event from physical, emotional, psychological, and financial perspectives. The lack of awareness of MHRA reporting structures and the lack of regulation within the UK's cosmetic injectables sector represent a significant public health challenge