Health workers’ knowledge, attitude and practice towards Hepatitis B infection in Northern Nigeria

Background: Infection by hepatitis B virus is one of the many challenges in public health today and the tenth leading cause of mortality worldwide. Research has shown that health-care personnel are at higher risk of acquiring the disease than the general population. Aim: The aim of this study was to investigate the relationship between knowledge, attitude and practice among health workers towards hepatitis B infection in Northern Nigeria. Methods: This study used a cross-sectional survey with self-administered questionnaire to gather information from an Ear, Nose and Throat health-care professionals in a tertiary hospital in Northern Nigeria. The data collected was coded and analyzed using SPSS software version 20. Results: A similar numbers of males, 49.5% (53/107), and females, 50.5% (54/107) took part. The overall correctly answered knowledge questions by the professions was 76.9%. A one-way ANOVA between participants showed that there were significant difference between the profession groups in terms of knowledge scores (F4, 102 = 11.5, P< 0.001) and in terms of practice scores between the groups (F4, 102 = 4.1, P<0.01); however, there was no significant difference in attitude between the professional groups (F4, 102 = 0.6, P= 0.68). Multivariate analysis showed that health attendants had the best practice score and did not differ significantly to Doctors (β = −0.1, t =−0.9, P= 0.40). Conclusion: The findings suggest that there is a gap in knowledge and lack of compliance to infection control and preventive measures among health-care professionals. There should be an increased in awareness through campaigns geared towards educating health-care personnel on the dangers of hepatitis B infection. Keywords: Health care workers, Hepatitis B infection, prevention and control, Knowledge, attitude and practice, Developing countrie

A systematic review of the use of an expertise-based randomised controlled trial design

Acknowledgements JAC held a Medical Research Council UK methodology (G1002292) fellowship, which supported this research. The Health Services Research Unit, Institute of Applied Health Sciences (University of Aberdeen), is core-funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. Views express are those of the authors and do not necessarily reflect the views of the funders.Peer reviewedPublisher PD

On Multiphase-Linear Ranking Functions

Multiphase ranking functions ($\mathit{M{\Phi}RFs}$) were proposed as a means to prove the termination of a loop in which the computation progresses through a number of "phases", and the progress of each phase is described by a different linear ranking function. Our work provides new insights regarding such functions for loops described by a conjunction of linear constraints (single-path loops). We provide a complete polynomial-time solution to the problem of existence and of synthesis of $\mathit{M{\Phi}RF}$ of bounded depth (number of phases), when variables range over rational or real numbers; a complete solution for the (harder) case that variables are integer, with a matching lower-bound proof, showing that the problem is coNP-complete; and a new theorem which bounds the number of iterations for loops with $\mathit{M{\Phi}RFs}$. Surprisingly, the bound is linear, even when the variables involved change in non-linear way. We also consider a type of lexicographic ranking functions, $\mathit{LLRFs}$, more expressive than types of lexicographic functions for which complete solutions have been given so far. We prove that for the above type of loops, lexicographic functions can be reduced to $\mathit{M{\Phi}RFs}$, and thus the questions of complexity of detection and synthesis, and of resulting iteration bounds, are also answered for this class.Comment: typos correcte

Using e-cigarettes for smoking cessation : evaluation of a pilot project in the North West of England

Aims: E-cigarettes have been advocated as an effective smoking cessation intervention, with evidence indicating that they are substantially less harmful than conventional cigarettes. As a result, a pilot to encourage people to swap from conventional cigarettes to e-cigarettes was conducted in 2018 in a socially deprived area in the North West of England. This evaluation highlights the key findings from the pilot. Methods: An analysis of secondary data at 4 weeks (n = 1022) was undertaken to predict those who used solely used e-cigarettes (i.e. had quit tobacco, as confirmed by a carbon monoxide test, CO < 10 ppm) from baseline characteristics, using chi-square tests and logistic regression. Baseline data were demographics, smoking levels and service provider type. Results: Of the 1022 participants who engaged with the pilot 614 were still engaged at 4 weeks, of whom 62% had quit; quitting was more likely in younger participants (aged 18–24) and less likely in those who were sick and disabled. Of those who still smoked tobacco at week 4 (n = 226), smoking had reduced from a baseline of 19.1 cigarettes/day to 8.7. Overall, 37% (381) of those initially enrolled were confirmed to be using an e-cigarette on its own at follow-up. Successful quit was associated with occupation (unemployed, 33% vs intermediate, 47%, p = .023) and residing in the less deprived quintiles of deprivation (50% vs 34% in the most deprived quintile, p = .016). Conclusions: Making the conservative assumption that all those not in contact at 4 weeks were still smoking tobacco, for every five people entering the scheme, three people stayed on the programme and reduced their cigarette smoking and one person cut out tobacco altogether. E-cigarettes appear to be an effective nicotine replacement therapy; however, further research is required to determine whether e-cigarette users are more likely to reduce their overall nicotine consumption in the longer term

Acetabular labrum reconstruction with fresh meniscus allograft transplantation : validation in a preclinical canine model

"Acetabular labrum pathology is frequently diagnosed in young, active individuals. Methods of hip preservation emphasize recapitulation of labrum structure and function to re-establish joint health and mitigate the development of hip osteoarthritis (OA). Labrum reconstruction utilizing fresh, frozen tendon allograft has become a popular option based on good short-term outcomes, however, failure rates are ~24%. Meniscus allograft has demonstrated early success as an alternative due to similarities in geometry, tissue composition, and metabolic profile when compared to acetabular labrum tissue. Healing of the fresh (viable) meniscus allografts transplantation (MAT) has not been well characterized."--Introduction

A day in the life of marine sulfonates

Lab-based studies, combined with metatranscriptomic and metabolomic field analyses, reveal important diel-linked roles for sulfonates in the major classes of phytoplankton that produce them, and in the environment in which they feed ubiquitous heterotrophic bacteri