Reply to Comments of Bassi, Ghirardi, and Tumulka on the Free Will Theorem

We show that the authors in the title have erred in claiming that our axiom FIN is false by conflating it with Bell locality. We also argue that the predictions of quantum mechanics, and in particular EPR, are fully Lorentz invariant, whereas the Free Will Theorem shows that theories with a mechanism of reduction, such as GRW, cannot be made fully invariant.Comment: We sharpen our theorem by replacing axiom FIN by a weaker axiom MIN to answer the above authors' objection

Surveying Eighty-Year-Old Battlefields in Solomon Islands

Surveying battlefield sites and abandoned ammunition depots eighty years after a conflict presents a challenge. There are few living witnesses, and the land has often changed beyond recognition. In Solomon Islands, the situation is exacerbated by a combination of familiarity and lack of information. Civilians have grown accustomed to the presence of ordnance and concluded that the problem is intractable. At the same time, it is not known how many people have died or been injured because of unexploded ordnance (UXO) and abandoned (AXO) ordnance. Nor is it known where the accidents occurred or what the victims were doing at the time of the accident. This lack of accident data has made it difficult for Solomon Islands to draw attention to the scale of the problem and request help through the assistance clauses of treaties including the Convention on Certain Conventional Weapons and the Anti-Personnel Mine Ban Convention. It makes it nearly impossible to write a national casualty reduction strategy built on solid data

Molecular clocks: Defusing the Cambrian ‘explosion’?

AbstractA recent molecular phylogenetic study argues against the orthodox view that metazoan phyla emerged abruptly during the Cambrian ‘explosion’, pointing instead to a protracted history for metazoans that arguably stretches back a billion years or more; the fossils, however, seem to tell a different story

Evolution: like any other science it is predictable

Evolutionary biology rejoices in the diversity of life, but this comes at a cost: other than working in the common framework of neo-Darwinian evolution, specialists in, for example, diatoms and mammals have little to say to each other. Accordingly, their research tends to track the particularities and peculiarities of a given group and seldom enquires whether there are any wider or deeper sets of explanations. Here, I present evidence in support of the heterodox idea that evolution might look to a general theory that does more than serve as a tautology (‘evolution explains evolution’). Specifically, I argue that far from its myriad of products being fortuitous and accidental, evolution is remarkably predictable. Thus, I urge a move away from the continuing obsession with Darwinian mechanisms, which are entirely uncontroversial. Rather, I emphasize why we should seek explanations for ubiquitous evolutionary convergence, as well as the emergence of complex integrated systems. At present, evolutionary theory seems to be akin to nineteenth-century physics, blissfully unaware of the imminent arrival of quantum mechanics and general relativity. Physics had its Newton, biology its Darwin: evolutionary biology now awaits its Einstein

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis

Mammalian Kiaa1211 and Kiaa1211-like are a homologous pair of uncharacterized, highly conserved genes cloned from fetal and adult brain cDNA libraries. Herein we map the in utero spatiotemporal expression of mKiaa1211 and mKiaa1211L mRNA and their expression patterns in postnatal testis, skin, gastrointestinal, and adipose progenitor tissues. Significantly, mKiaa1211 is present throughout the early stages of mouse heart development, particularly in the second heart field (SHF) lineage as it differentiates from mesenchymal cells into cardiomyocytes. We also show that mKiaa1211 is expressed within several early neuronal tissues destined to give rise to central, peripheral, and sympathetic nervous system structures. Expression profiling revealed that the paralog mKiaa1211L is not expressed during the normal developmental process and that mKiaa1211 expression was noticeably absent from most adult terminally differentiated tissues. Finally, we confirm that a previously uncharacterized CRISPR/CAS-generated mKiaa1211 mouse mutant allele is hypomorphic