On the origin of leprosy.

International audienceLeprosy, a chronic human disease with potentially debilitating neurological consequences, results from infection with Mycobacterium leprae. This unculturable pathogen has undergone extensive reductive evolution, with half of its genome now occupied by pseudogenes. Using comparative genomics, we demonstrated that all extant cases of leprosy are attributable to a single clone whose dissemination worldwide can be retraced from analysis of very rare single-nucleotide polymorphisms. The disease seems to have originated in Eastern Africa or the Near East and spread with successive human migrations. Europeans or North Africans introduced leprosy into West Africa and the Americas within the past 500 years

Desarrollo de una vacuna contra la Leishmaniasis cutánea en sus aspectos de inmunoterapia y posible aplicación en inmunoprofilaxis

In this article, they are mentioned the investigational papers that have been carried out in the institute of Biomedicina, about the development of a vaccine against American Cutaneous Leishmaniasis. These papers have been based on the spectrum of clinical-immunological manifestations of the illness, as well as their possible application in inmunoprophylaxis, by the study of possible action mechanisms of the mixture of dead Leishmania promastigotes plus viable Bacillus of Calmette-Guerin, that are the components of the vaccine developed in this institute

JACINTO CONVIT UNA VIDA DEDICADO A LA INVESTIGACIÓN SOBRE VACUNAS

“Cada vez que nos lancen una piedra, debemos devolverles una rosa. Porque el amor es el único antídoto contra el odio»