90 research outputs found

    A Walk in Memphis - Post 16 Introductory Project for Design

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    Team building and team management pose one of the greatest challenges to a head offaculty. There is no doubt that people represent the greatest resource in terms of expertise and investment and demand the greatest leadership. At Beauchamp the head offaculty has risen to the challenge through a collaborative approach to introducing post-16 design courses

    Reviews

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    The following publications have been reviewed by the mentioned authors;GCSE Design and Technology - Resistant Materials - reviewed by Alison HardyGCSE Design and Technology - Textiles Technology - reviewed by Julie BoydIssues in Design and Technology Teaching - reviewed by John DurrellAgriculture in the Food Supply Chain: an overview - reviewed by Anne ConstableFood Chemical Composition: dietary significance in food manufacturing - reviewed by Anne ConstableFood The Chemistry of its Components - reviewed by Brenda Greatwoo

    Verifying participant-reported clinical outcomes : challenges and implications

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    The parent trials KAT, REFLUX and CATHETER were all funded by the UK NIHR Health Technology Assessment Programme. RECORD was funded by the UK Medical Research Council. Suzanne Breeman and Lynda Constable are joint first authors.Peer reviewedPublisher PD

    Dietary strategies for improving iron status: balancing safety and efficacy.

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    In light of evidence that high-dose iron supplements lead to a range of adverse events in low-income settings, the safety and efficacy of lower doses of iron provided through biological or industrial fortification of foodstuffs is reviewed. First, strategies for point-of-manufacture chemical fortification are compared with biofortification achieved through plant breeding. Recent insights into the mechanisms of human iron absorption and regulation, the mechanisms by which iron can promote malaria and bacterial infections, and the role of iron in modifying the gut microbiota are summarized. There is strong evidence that supplemental iron given in nonphysiological amounts can increase the risk of bacterial and protozoal infections (especially malaria), but the use of lower quantities of iron provided within a food matrix, ie, fortified food, should be safer in most cases and represents a more logical strategy for a sustained reduction of the risk of deficiency by providing the best balance of risk and benefits. Further research into iron compounds that would minimize the availability of unabsorbed iron to the gut microbiota is warranted

    Climate change impacts on polar marine ecosystems: Toward robust approaches for managing risks and uncertainties

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    The Polar Regions chapter of the Intergovernmental Panel on Climate Change's Special Report on the Ocean and Cryosphere in a Changing Climate (SROCC) provides a comprehensive assessment of climate change impacts on polar marine ecosystems and associated consequences for humans. It also includes identification of confidence for major findings based on agreement across studies and weight of evidence. Sources of uncertainty, from the extent of available datasets, to resolution of projection models, to the complexity and understanding of underlying social-ecological linkages and dynamics, can influence confidence. Here we, marine ecosystem scientists all having experience as lead authors of IPCC reports, examine the evolution of confidence in observed and projected climate-linked changes in polar ecosystems since SROCC. Further synthesis of literature on polar marine ecosystems has been undertaken, especially within IPCC's Sixth Assessment Report (AR6) Working Group II; for the Southern Ocean also the Marine Ecosystem Assessment for the Southern Ocean (MEASO). These publications incorporate new scientific findings that address some of the knowledge gaps identified in SROCC. While knowledge gaps have been narrowed, we still find that polar region assessments reflect pronounced geographical skewness in knowledge regarding the responses of marine life to changing climate and associated literature. There is also an imbalance in scientific focus; especially research in Antarctica is dominated by physical oceanography and cryosphere science with highly fragmented approaches and only short-term funding to ecology. There are clear indications that the scientific community has made substantial progress in its ability to project ecosystem responses to future climate change through the development of coupled biophysical models of the region facilitated by increased computer power allowing for improved resolution in space and time. Lastly, we point forward—providing recommendations for future advances for IPCC assessments.publishedVersio

    Towards Bridging the Gap Between Programming Languages and Partial Evaluation

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    International audiencePartial evaluation is a program-transformation technique that automatically specializes a program with respect to user-supplied invariants. Despite successful applications in areas such as graphics, operating systems, and software engineering, partial evaluators have yet to achieve widespread use. One reason is the difficulty of adequately describing specialization opportunities. Indeed, under-specialization or over-specialization often occurs, without any direct feedback to the user as to the source of the problem. We have developed a high-level, module-based language allowing the programmer to guide the choice of both the code to specialize and the invariants to exploit during the specialization process. To ease the use of partial evaluation, the syntax of this language is similar to the declaration syntax of the target language of the partial evaluator. To provide feedback to the programmer, declarations are checked throughout the analyses performed by partial evaluation. The language has been successfully used by a signal-processing expert in the design of a specializable Forward Error Correction component
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