Proteoform: a single term describing protein complexity

Consortium for Top Down Proteomics members: Deborah Penque (INSA, IP)Support of the US National Institutes of Health (1R01GM067193 to N.L.K., 1P50HG004952 to L.M.S.) and a grant to N.L.K. from the Chicago Biomedical Consortium, which is supported by the Searle Funds at The Chicago Community Trust

Limitless translation limits translation

Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to form ‘traffic jams’ that inhibit protein expression