2,306 research outputs found

    'Give me my pathway!’: Multinational migration, transnational skills regimes and migrant subjectification

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    In this article, I address the interplay between migration regimes and migrant subjectivities in stepwise multinational migration through a comparative analysis of biographical interviews with migrants in the healthcare and dairy farm work sectors in New Zealand. In both sectors, migrants' trajectories involve movements from Asia to locations in the Middle East, North Africa or Japan before arrival in New Zealand, and in some cases plans for onward migration. The analysis of these migration patterns and the narratives of migrants, reveal an emergent transnational skills regime that involves connected but uncoordinated systems of skills recognition; negotiating this regime occurs through increased attunement to migration on the part of multinational migrants, as well as adaptation to the expectations of authorities and employers. I conclude the article by suggesting that while multinational migration involves new opportunities for people on the move it also entails greater entanglement in the unequal conditioning of transnational migration

    Performance of Solid-State Sensors for Continuous, Real-Time Measurement of Soil CO\u3csub\u3e2\u3c/sub\u3e Concentrations

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    Recent advances in sensor technology provide a robust capability for continuous measurement of soil gases. The performance of solid-state CO2 sensors (Model GMM220 series, Vaisala, Inc., Helsinki, Finland) was evaluated in laboratory, greenhouse, and irrigated winter wheat (Triticum aestivum L.). In ambient CO2 concentration, the GMM222 sensor averaged 427 ± 8.3 ÎŒL L−1. Under variable CO2 concentrations, the sensor was slightly lower than concentrations measured with an infrared gas analyzer (IRGA). In greenhouse pots planted with triticale (Triticale hexaploide Lart.) and an agricultural field of irrigated winter wheat, soil CO2 concentration exceeded the 10,000 ÎŒL L−1 limit of the GMM222. Alternatively, the GMM221 sensor, designed to measure between 0 and 20,000 ÎŒL L−1, showed soil CO2 concentrations were between 14,000 and 16,000 ÎŒL L−1. The GMM222 accurately measures real-time soil CO2 concentrations under field conditions that were within the sensor detection limit. However, periods of high biological soil activity require the GMM221 sensor with a higher detection limit

    A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX

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    BACKGROUND: Genome-wide association studies (GWAS) identify regions of the genome that are associated with particular traits, but do not typically identify specific causative genetic elements. For example, while a large number of single nucleotide polymorphisms associated with type 2 diabetes (T2D) and related traits have been identified by human GWAS, only a few genes have functional evidence to support or to rule out a role in cellular metabolism or dietary interactions. Here, we use a recently developed Drosophila model in which high-sucrose feeding induces phenotypes similar to T2D to assess orthologs of human GWAS-identified candidate genes for risk of T2D and related traits. RESULTS: Disrupting orthologs of certain T2D candidate genes (HHEX, THADA, PPARG, KCNJ11) led to sucrose-dependent toxicity. Tissue-specific knockdown of the HHEX ortholog dHHEX (CG7056) directed metabolic defects and enhanced lethality; for example, fat-body-specific loss of dHHEX led to increased hemolymph glucose and reduced insulin sensitivity. CONCLUSION: Candidate genes identified in human genetic studies of metabolic traits can be prioritized and functionally characterized using a simple Drosophila approach. To our knowledge, this is the first large-scale effort to study the functional interaction between GWAS-identified candidate genes and an environmental risk factor such as diet in a model organism system

    A Pair of Compact Red Galaxies at Redshift 2.38, Immersed in a 100 kpc Scale Ly-alpha Nebula

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    We present Hubble Space Telescope (HST) and ground-based observations of a pair of galaxies at redshift 2.38, which are collectively known as 2142-4420 B1 (Francis et al. 1996). The two galaxies are both luminous extremely red objects (EROs), separated by 0.8 arcsec. They are embedded within a 100 kpc scale diffuse Ly-alpha nebula (or blob) of luminosity ~10^44 erg/s. The radial profiles and colors of both red objects are most naturally explained if they are young elliptical galaxies: the most distant yet found. It is not, however, possible to rule out a model in which they are abnormally compact, extremely dusty starbursting disk galaxies. If they are elliptical galaxies, their stellar populations have inferred masses of ~10^11 solar masses and ages of ~7x10^8 years. Both galaxies have color gradients: their centers are significantly bluer than their outer regions. The surface brightness of both galaxies is roughly an order of magnitude greater than would be predicted by the Kormendy relation. A chain of diffuse star formation extending 1 arcsec from the galaxies may be evidence that they are interacting or merging. The Ly-alpha nebula surrounding the galaxies shows apparent velocity substructure of amplitude ~ 700 km/s. We propose that the Ly-alpha emission from this nebula may be produced by fast shocks, powered either by a galactic superwind or by the release of gravitational potential energy.Comment: 33 pages, 9 figures, ApJ in press (to appear in Jun 10 issue

    Racism and Employment: A Narrative Review of Aotearoa New Zealand and International Qualitative Studies

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    In Aotearoa New Zealand, employment inequities exist for minoritised ethnic groups (Māori, Pasifika, Asian, racialised migrants and refugees) in the forms of barriers to employment, occupation inequities, differences in promotion to leadership roles, ethnic pay gaps and discriminatory experiences at workplaces. In this review, we compiled Aotearoa qualitative studies to depict the dynamics of racism alongside other intersectional forms of prejudices that disadvantage the employment processes and career progression of minoritised ethnicities. Literature gaps in Aotearoa research were identified through reviewing international literature published between 2016 and 2021. Reviewed Aotearoa studies were categorised into three themes: unemployment and underemployment, workplace discrimination, and strategies for navigating racism. Drawing upon a framework that recognises racialised processes as spanning across micro- (individual), meso- (organisational) and macro- (institutional) levels, we found most Aotearoa studies analysing racism in the workplace focus on micro-level experiences. Compared with international literature, research in Aotearoa has yet to consider the roles of organisations and technologies as racialised structures that engender employment inequities, and the interaction of individuals in response to meso- and macro-structures that build on settler colonialism and racism. Our review echoes the call of Aotearoa scholars to name racism as the overarching oppressive mechanism embedded within organisations and to use anti-racism praxes such as te Tiriti o Waitangi as a way forward to promote employment equity

    Population diversity in Aotearoa New Zealand: Insights from the CaDDANZ research programme

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    CaDDANZ was a New Zealand Government-funded project studying the impacts of growing population diversity in Aotearoa New Zealand. The project ran from 2014 to 2020 and was extended to March 2021 due to the effects of the global COVID-19 pandemic. Staffed by a multidisciplinary team of researchers, CaDDANZ aimed to identify changing demographics and the impacts of ethnic and demographic diversity on aspects of economic and social change. This report has synthesised a bundle of key insights that could only have surfaced through the reflection on the interplay between the research questions that the original bid set out to address. While we, as a project team, did not intend to produce transdisciplinary or even interdisciplinary work on migration, diversity or the diversity dividend, setting a goal to synthesise something from the project as a whole has produced this report. Using social cohesion as a sorting mechanism for the insights has meant this overview is selective and high level. Not all the projects can be read against a social cohesion or even social inclusion lens. In particular, many of the econometric outputs explicitly addressed aspects of diversity as an economic dividend and that work is not highlighted in the synthesis. Three broad themes are addressed 1. Immigration and diversity – understanding population trends 2. [Re] conceptualising ethno-demographic diversity in Aotearoa – Tangata whenua perspectives 3. Diversity in context – in different settings and over time The report concludes with four high-level insights 1. Immigration policy needs to re-examine its position in relation to Tiriti o Waitangi where any Crown partnership relationship is currently lacking. 2. Despite social cohesion being a negotiated term, its use as a framing for the impacts of migration on both the host country and individual migrant lives is underpinned by its use in the Royal Commission of Inquiry into the terrorist attack on Christchurch mosques on 15 March 2019 and is preferable to the concept of a diversity dividend.1 3. While ethnocultural diversity is the default for ‘diversity dividend’ research, the concept of the social organisation of difference has broader relevance to social justice-oriented policy development.2 4. The use of wide range of different methodologies is vital for the production of wellevidenced, theory-informed strategies and policies

    Creativity in Citizen Cyberscience

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    An interview study was conducted to explore volunteers’ experiences of creativity in citizen cyberscience. Participants were recruited from 4 projects: GeoTag-X, Virtual Atom Smasher, Synthetic Biology, and Extreme Citizen Science. Ninety-six interviews were conducted in total: 86 with volunteers (citizen scientists) and 10 with professional scientists. The resulting thematic analysis revealed that volunteers are involved in a range of creative activities, such as discussing ideas, suggesting improvements, gamification, artwork, creative writing, and outreach activities. We conclude that the majority of creative products are community-related. Creativity in citizen cyberscience is a collective process: volunteers create within a project and a community, both for themselves and for others

    The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

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    The Metabolic Syndrome in Men (METSIM) study is a population-based study including 10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate nongenetic and genetic factors associated with the risk of T2D and CVD, and with cardiovascular risk factors. The protocol includes a detailed phenotyping of the participants, an oral glucose tolerance test, fasting laboratory measurements including proton NMR measurements, mass spectometry metabolomics, adipose tissue biopsies from 1,400 participants, and a stool sample. In our ongoing follow-up study, we have, to date, reexamined 6,496 participants. Extensive genotyping and exome sequencing have been performed for essentially all METSIM participants, and >2,000 METSIM participants have been whole-genome sequenced. We have identified several nongenetic markers associated with the development of diabetes and cardiovascular events, and participated in several genetic association studies to identify gene variants associated with diabetes, hyperglycemia, and cardiovascular risk factors. The generation of a phenotype and genotype resource in the METSIM study allows us to proceed toward a “systems genetics” approach, which includes statistical methods to quantitate and integrate intermediate phenotypes, such as transcript, protein, or metabolite levels, to provide a global view of the molecular architecture of complex traits

    Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subjects: novel MRI insights

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    BACKGROUND/OBJECTIVES: Postprandial bloating is a common symptom in patients with functional gastrointestinal (GI) diseases. Whole meal bread (WMB) often aggravates such symptoms though the mechanisms are unclear. We used magnetic resonance imaging (MRI) to monitor the intragastric fate of a WMB meal (11% bran) compared to a rice pudding (RP) meal. SUBJECTS/METHODS: 12 healthy volunteers completed this randomised crossover study. They fasted overnight and after an initial MRI scan consumed a glass of orange juice with a 2267 kJ WMB or an equicaloric RP meal. Subjects underwent serial MRI scans every 45 min up to 270 min to assess gastric volumes and small bowel water content and completed a GI symptom questionnaire. RESULTS: The MRI intragastric appearance of the two meals was markedly different. The WMB meal formed a homogeneous dark bolus with brighter liquid signal surrounding it. The RP meal separated into an upper, liquid layer and a lower particulate layer allowing more rapid emptying of the liquid compared to solid phase (sieving). The WMB meal had longer gastric half emptying times (132±8 min) compared to the RP meal (104±7 min), P<0.008. The WMB meal was associated with markedly reduced MRI-visible small bowel free mobile water content compared to the RP meal, P<0.0001. CONCLUSIONS: WMB bread forms a homogeneous bolus in the stomach which inhibits gastric sieving and hence empties slower than the equicaloric rice meal. These properties may explain why wheat causes postprandial bloating and could be exploited to design foods which prolong satiation

    The Halos and Environments of Nearby Galaxies (HERON) Survey

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    We have used dedicated 0.7m telescopes in California and Israel to image the halos of ~200 galaxies in the Local Volume to 29 mag/sq arcsec, the sample mainly drawn from the 2MASS Large Galaxy Atlas (LGA). We supplement the LGA sample with dwarf galaxies and more distant giant ellipticals. Low surface brightness halos exceeding 50 kpc in diameter are found only in galaxies more luminous than L* and classic interaction signatures are relatively infrequent. Halo diameter is correlated with total galaxy luminosity. Extended low surface brightness halos are present even in galaxies as faint as M_V=-18. Edge-on galaxies with boxy bulges tend to lack extended spheroidal halos, while those with large classical bulges exhibit extended round halos, supporting the notions that boxy or barlike bulges originate from disks. Most face-on spiral galaxies present features that appear to be irregular extensions of spiral arms, although rare cases show smooth boundaries with no sign of star formation. Although we serendipitously discovered a dwarf galaxy undergoing tidal disruption in the halo of NGC 4449, we found no comparable examples in our general survey. A search for similar examples in the Local Volume identified hcc087, a tidally disrupting dwarf galaxy in the Hercules Cluster, but we do not confirm an anomalously large half-light radius reported for the dwarf VCC 1661
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