Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): study protocol for a randomized controlled trial

Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11–17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75–85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55–75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources.The HEPAFIT study was carried out with the financial support of Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología “Francisco José de Caldas” COLCIENCIAS (code 59700 and no 122277757900). Katherine González-Ruíz receive a scholarship from Universidad del Rosario, Colombia, Escuela de Medicina y Ciencias de la Salud, to do a Doctorate. This article presents independent research commissioned by COLCIENCIAS under its Program Grants for Applied Research funding scheme (Convocatoria 777–2017)

Análise da sintomatologia depressiva nos moradores do Abrigo Cristo Redentor através da aplicação da Escala de Depressão Geriátrica (EDG) Analysis of depression in elderly living in the shelter " Christ the Redeemer" , applying the Scale of Geriatric Depression (SGD)

O objetivo do estudo foi determinar a prevalência de depressão em idosos que residem no Abrigo Cristo Redentor, Jaboatão dos Guararapes, Pernambuco. Foi realizado estudo descritivo no período de setembro e outubro de 2006, com idosos de idade igual ou acima de 60 anos. A amostra foi composta de 55 idosos, que responderam à Escala de Depressão Geriátrica de Yesavage, com trinta perguntas. Foram realizadas análises de variância da prevalência dos sintomas de depressão entre ambos os sexos. A depressão foi identificada em 28 idosos (51%), dentre os quais dezoito homens (64,3%) e dez mulheres (35,7%). Recomenda-se a criação de uma nova escala, mais simples e de entendimento mais fácil, para pacientes que têm nível cognitivo rebaixado.<br>The objective of this study was to determine the prevalence of depression in elderly living in the shelter " Christ the Redeemer" , in Jaboatão dos Guararapes, Pernambuco. A descriptive study was conducted in September and October 2006, with individuals aged 60 years or more. The sample consisted of 55 elderly, who answered the 30 questions of the Scale of Geriatric Depression of Yesavage. Analysis of variance of the prevalence of depression symptoms between both sexes was conducted. Depression was identified in 28 individuals (51%), 18 males (64,2%) and 10 females (35,7%). We recommend the creation of a new scale, simpler and easier to understand for patients with lower cognitive level