152 research outputs found
Is Your Brand Going Out of Fashion? A Quantitative, Causal Study Designed to Harness the Web for Early Indicators of Brand Value
Can Internet search query data be a relevant predictor of financial measures of brand value? Can Internet search query data enrich existing financial measures of brand valuation tools and provide more timely insights to brand managers? Along with the financial based motivation to estimate the value of a brand for accounting purposes, marketers desire to show “accountability” of marketing activity and respond to the customer’s perception of the brand quickly to maintain their competitive advantage and value. The usefulness of the “consumer information processing” framework for brand, consumer and firm forecasting is examined. To develop our hypotheses, we draw from the growing body of work relating web searches to real world outcomes, to determine if a search query for a brand is causal to, and potentially predictive of brand, consumer and firm value. The contribution to current literature is that search queries can predict perception, whereas previous research in this nascent area predicted behavior and events. In this direction, we propose arguments underpinning this research as follows: the theoretical background relative to brand valuation and the theoretical frame based on an in-depth review of how scholars have used search query data as a predictive measure across several disciplines including economics and the health sciences. From a practitioner perspective, unlike traditional valuation methods search query data for brands is more timely, actionable, and inclusive
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The face of Oregon's library community
One goal of the Oregon Library Association's Vision 2010 is to promote a strong and diverse workforce throughout all of the state's libraries. The forecasted shortage of librarians in the next decade prompted the OLA Board to request a demographic study of Oregon's libraries. A simple survey was adminstered at the annual conferences of OLA and OEMA, and the results presented. Ideas for addressing a possible shortage of librarians are suggested.Keywords: Librarians/status, Librarians/Oregon, Recruiting for librarianship, Surveys/Librarians, Librarians/supply and demandKeywords: Librarians/status, Librarians/Oregon, Recruiting for librarianship, Surveys/Librarians, Librarians/supply and deman
Increased brain age in adults with Prader-Willi syndrome.
Prader-Willi syndrome (PWS) is the most common genetic obesity syndrome, with associated learning difficulties, neuroendocrine deficits, and behavioural and psychiatric problems. As the life expectancy of individuals with PWS increases, there is concern that alterations in brain structure associated with the syndrome, as a direct result of absent expression of PWS genes, and its metabolic complications and hormonal deficits, might cause early onset of physiological and brain aging. In this study, a machine learning approach was used to predict brain age based on grey matter (GM) and white matter (WM) maps derived from structural neuroimaging data using T1-weighted magnetic resonance imaging (MRI) scans. Brain-predicted age difference (brain-PAD) scores, calculated as the difference between chronological age and brain-predicted age, are designed to reflect deviations from healthy brain aging, with higher brain-PAD scores indicating premature aging. Two separate adult cohorts underwent brain-predicted age calculation. The main cohort consisted of adults with PWS (n = 20; age mean 23.1 years, range 19.8-27.7; 70.0% male; body mass index (BMI) mean 30.1 kg/m2, 21.5-47.7; n = 19 paternal chromosome 15q11-13 deletion) and age- and sex-matched controls (n = 40; age 22.9 years, 19.6-29.0; 65.0% male; BMI 24.1 kg/m2, 19.2-34.2) adults (BMI PWS vs. control P = .002). Brain-PAD was significantly greater in PWS than controls (effect size mean ± SEM +7.24 ± 2.20 years [95% CI 2.83, 11.63], P = .002). Brain-PAD remained significantly greater in PWS than controls when restricting analysis to a sub-cohort matched for BMI consisting of n = 15 with PWS with BMI range 21.5-33.7 kg/m2, and n = 29 controls with BMI 21.7-34.2 kg/m2 (effect size +5.51 ± 2.56 years [95% CI 3.44, 10.38], P = .037). In the PWS group, brain-PAD scores were not associated with intelligence quotient (IQ), use of hormonal and psychotropic medications, nor severity of repetitive or disruptive behaviours. A 24.5 year old man (BMI 36.9 kg/m2) with PWS from a SNORD116 microdeletion also had increased brain PAD of 12.87 years, compared to 0.84 ± 6.52 years in a second control adult cohort (n = 95; age mean 34.0 years, range 19.9-55.5; 38.9% male; BMI 28.7 kg/m2, 19.1-43.1). This increase in brain-PAD in adults with PWS indicates abnormal brain structure that may reflect premature brain aging or abnormal brain development. The similar finding in a rare patient with a SNORD116 microdeletion implicates a potential causative role for this PWS region gene cluster in the structural brain abnormalities associated primarily with the syndrome and/or its complications. Further longitudinal neuroimaging studies are needed to clarify the natural history of this increase in brain age in PWS, its relationship with obesity, and whether similar findings are seen in those with PWS from maternal uniparental disomy
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