2,218 research outputs found

    The climate deception dossiers: internal fossil fuel industry memos reveal decades of corporate disinformation

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    This report presents seven “deception dossiers”—collections containing some 85 internal company and trade association documents that have either been leaked to the public, come to light through lawsuits, or been disclosed through Freedom of Information Act (FOIA) requests. While many of these documents have been analyzed by others (Oreskes 2011; Oreskes and Conway 2010; Gelbspan 1998), these dossiers offer the most complete and up-to-date collection yet available. Excerpts of the documents are provided in the report’s appendices; the complete dossiers—totaling some 336 pages— are available online. Each collection of internal documents reviewed here reveals a separate glimpse of a coordinated campaign underwritten by the world’s major fossil fuel companies and their allies to spread climate misinformation and block climate action. The campaign began decades ago and continues today. The fossil fuel industry—like the tobacco industry before it—is noteworthy for its use of active, intentional disinformation and deception to support its political aims and maintain its lucrative profits. The following case studies show that: Fossil fuel companies have intentionally spread climate disinformation for decades. The roots of the fossil fuel companies’ deception and disinformation run deep. Internal documents dating back to the early 1990s show a series of carefully planned campaigns of deception organized by companies and by trade groups representing the industry. As the scientific evidence concerning climate change became clear, some of the world’s largest carbon producers—including BP, Chevron, ConocoPhillips, ExxonMobil, Peabody Energy, and Shell—developed or participated in campaigns to deliberately sow confusion and block policies designed to reduce the heat-trapping emissions that cause global warming. Fossil fuel company leaders knew that their products were harmful to people and the planet but still chose to actively deceive the public and deny this harm. The letters, memos, and reports in the dossiers show that company executives have known for at least two decades that their products—coal, oil, and natural gas—cause harm to people and the climate. The campaign of deception continues today. With documents made public as recently as 2014 and 2015, the evidence is clear that a campaign of deception about global warming continues to the present. Today, most major fossil fuel companies acknowledge the main findings of climate science. Many even say they support policies to cut emissions. And yet, some of these same companies continue to support groups that spread misinformation designed to deceive the public about climate science and climate policy

    Targeting paleovalley-related ferricrete units in yilgarn craton using high-resolution aeromagnetic data and spatial machine learning

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    The ferricrete units (Fe oxide cemented colluvial-alluvial sediment) of the Yilgarn Craton in Western Australia formed during the humid tropical and sub-tropical climates of the Cenozoic. Ferricretes are generally developed on long-lived paleodrainage systems and are products of the ferruginisation of detritus provided by the continuous erosion of upslopes. These iron-rich accumulations can become Au-enriched, as is the case in several locations previously discovered in the Yilgarn Craton; many of these host economic secondary gold deposits (e.g., Moolart Well, Mt Gibson, and Bulchina), typically occurring downslope of low saprolite hills and near paleovalleys (i.e., inset-valleys). Inset-valleys are a common paleotopographic feature buried under Quaternary alluvial and colluvial sedimentary cover. Maps of these ancient channel networks can be used as a proxy for targeting ferricrete gold deposits. These inset-valley systems generally form dendritic and noisy patterns in high-resolution aeromagnetic data due to the presence of maghemite-rich nodules and detrital magnetic pisoliths on their flanks. The main aim of this study was to use high-resolution aeromagnetic data to target ferricrete units related to inset-valleys systems across the Yilgarn Craton. A spatial predictive model was used to learn and predict the geological units of interest from pre-processed aeromagnetic data. The predicted inset-valleys systems were able to confine the exploration space and define a new exploration frontier for ferricrete gold deposits

    Lyman Alpha Emitters in the Hierarchically Clustering Galaxy Formation

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    We present a new theoretical model for the luminosity functions (LFs) of Lyman alpha (Lya) emitting galaxies in the framework of hierarchical galaxy formation. We extend a semi-analytic model of galaxy formation that reproduces a number of observations for local and high-z galaxies, without changing the original model parameters but introducing a physically-motivated modelling to describe the escape fraction of Lya photons from host galaxies (f_esc). Though a previous study using a hierarchical clustering model simply assumed a constant and universal value of f_esc, we incorporate two new effects on f_esc: extinction by interstellar dust and galaxy-scale outflow induced as a star formation feedback. It is found that the new model nicely reproduces all the observed Lya LFs of the Lya emitters (LAEs) at different redshifts in z ~ 3-6. Especially, the rather surprisingly small evolution of the observed LAE Lya LFs compared with the dark halo mass function is naturally reproduced. Our model predicts that galaxies with strong outflows and f_esc ~ 1 are dominant in the observed LFs. This is also consistent with available observations, while the simple universal f_esc model requires f_esc << 1 not to overproduce the brightest LAEs. On the other hand, we found that our model significantly overpredicts LAEs at z > 6, and absorption of Lya photons by neutral hydrogen in intergalactic medium (IGM) is a reasonable interpretation for the discrepancy. This indicates that the IGM neutral fraction x_HI rapidly evolves from x_HI << 1 at z < 6 to a value of order unity at z ~ 6-7, which is broadly consistent with other observational constraints on the reionization history.Comment: 14 pages, 7 figures, 1 table; accepted to ApJ; the html abstract is replaced to match the accepted version, the .ps and .pdf files are strictly identical between the 2nd and the 3rd version

    Formation of magnetite and iron-rich carbonates by thermophilic iron-reducing bacteria

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    Laboratory experiments were performed to study the formation of iron minerals by a thermophilic (45 - 75 degree(s)C) fermentative iron-reducing bacterial culture (TOR39) obtained from the deep subsurface. Using amorphous Fe(III) oxyhydroxide as an electron acceptor and glucose as an electron donor, TOR39 produced magnetite and iron-rich carbonates at conditions consistent, on a thermodynamic basis, with Eh (-200 mV to -415 mV) and pH (6.2 to 7.7) values determined for these experiments. Analyses of the precipitating solid phases by X-ray diffraction showed that the starting amorphous Fe(III) oxyhydroxide was nearly completely converted to magnetite and Fe-rich carbonate after 20 days of incubation. Increasing bicarbonate concentration in the chemical milieu resulted in increased proportions of siderite relative to magnetite and the addition of MgCl2 caused the formation of magnesium-rich carbonate in addition to siderite. The results suggest that the TOR39 bacterial culture may have the capacity to form magnetite and iron-rich carbonates in a variety of geochemical conditions. These results may have significant implications for studying the past biogenic activities in the Martian meteorite ALH84001

    Ethnically diverse urban transmission networks of Neisseria gonorrhoeae without evidence of HIV serosorting

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    Objective We aimed to characterise gonorrhoea transmission patterns in a diverse urban population by linking genomic, epidemiological and antimicrobial susceptibility data. Methods Neisseria gonorrhoeae isolates from patients attending sexual health clinics at Barts Health NHS Trust, London, UK, during an 11-month period underwent whole-genome sequencing and antimicrobial susceptibility testing. We combined laboratory and patient data to investigate the transmission network structure. Results One hundred and fifty-eight isolates from 158 patients were available with associated descriptive data. One hundred and twenty-nine (82%) patients identified as male and 25 (16%) as female; four (3%) records lacked gender information. Self-described ethnicities were: 51 (32%) English/Welsh/Scottish; 33 (21%) white, other; 23 (15%) black British/black African/black, other; 12 (8%) Caribbean; 9 (6%) South Asian; 6 (4%) mixed ethnicity; and 10 (6%) other; data were missing for 14 (9%). Self-reported sexual orientations were 82 (52%) men who have sex with men (MSM); 49 (31%) heterosexual; 2 (1%) bisexual; data were missing for 25 individuals. Twenty-two (14%) patients were HIV positive. Whole-genome sequence data were generated for 151 isolates, which linked 75 (50%) patients to at least one other case. Using sequencing data, we found no evidence of transmission networks related to specific ethnic groups (p=0.64) or of HIV serosorting (p=0.35). Of 82 MSM/bisexual patients with sequencing data, 45 (55%) belonged to clusters of ≥2 cases, compared with 16/44 (36%) heterosexuals with sequencing data (p=0.06). Conclusion We demonstrate links between 50% of patients in transmission networks using a relatively small sample in a large cosmopolitan city. We found no evidence of HIV serosorting. Our results do not support assortative selectivity as an explanation for differences in gonorrhoea incidence between ethnic groups

    Ethnically diverse urban transmission networks of Neisseria gonorrhoeae without evidence of HIV serosorting

    Get PDF
    Objective We aimed to characterise gonorrhoea transmission patterns in a diverse urban population by linking genomic, epidemiological and antimicrobial susceptibility data. Methods Neisseria gonorrhoeae isolates from patients attending sexual health clinics at Barts Health NHS Trust, London, UK, during an eleven-month period underwent whole-genome sequencing and antimicrobial susceptibility testing. We combined laboratory and patient data to investigate the transmission network structure. Results One hundred and fifty-eight isolates from 158 patients were available with associated descriptive data. One hundred and twenty-nine (82%) patients identified as male and 25 (16%) as female; 4 (3%) records lacked gender information. Self-described ethnicities were: 51 (32%) English/Welsh/Scottish; 33 (21%) White, other; 23 (15%) Black British/Black African/Black, other; 12 (8%) Caribbean; 9 (6%) South Asian; 6 (4%) mixed ethnicity; 10 (6%) other; data were missing for 14 (9%). Self-reported sexual orientations were 82 (52%) men who have sex with men; 49 (31%) heterosexual; 2 (1%) bisexual; data missing for 25 individuals. Twenty-two (14%) patients were HIV-positive. Whole genome sequence data were generated for 151 isolates, which linked 75 (50%) patients to at least one other case. Using sequencing data, we found no evidence of transmission networks related to specific ethnic groups (p=0.64) or of HIV serosorting (p=0.35). Of 82 MSM/bisexual patients with sequencing data, 45 (55%) belonged to clusters of ≥2 cases, compared to 16/44 (36%) heterosexuals with sequencing data (p=0.06). Conclusion We demonstrate links between 50% of patients in transmission networks using a relatively small sample in a large cosmopolitan city. We found no evidence of HIV serosorting. Our results do not support assortative selectivity as an explanation for differences in gonorrhoea incidence between ethnic groups

    The phase-diagram of the IGM and the entropy floor of groups and clusters: are clusters born warm?

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    We point out that two problems of observational cosmology, the facts i) that > 60% of the baryonic content of the universe is not observed at z=0 and ii) that the properties of small clusters do not agree with simple expectations, could be closely related. As shown by recent studies, the shock-heating associated with the formation of large-scale structures heats the intergalactic medium (IGM) and leads to a ``warm IGM'' component for the gas. In the same spirit, we suggest the intracluster medium (ICM) to be a mixture of galaxy-recycled, metal enriched gas and intergalactic gas, shock-heated by the collapsing much larger scales. This could be obtained through two processes: 1) the late infalling gas from the external warm IGM is efficiently mixed within the halo and brings some additional entropy, or 2) the shocks generated by larger non-linear scales are also present within clusters and can heat the ICM. We show that if assumption (1) holds, the entropy brought by the warm IGM is sufficient to explain the observed properties of clusters, in particular the entropy floor and the LX-T relation. On the other hand, we briefly note that the scenario (2) would require a stronger shock-heating because of the larger density of the ICM as compared with filaments. Our scenario of clusters being "born warm" can be checked through the predicted redshift evolution of the entropy floor.Comment: 8 pages, final version published in MNRA

    A Pilot Study Comparing the Efficacy of Lactate Dehydrogenase Levels Versus Circulating Cell-Free microRNAs in Monitoring Responses to Checkpoint Inhibitor Immunotherapy in Metastatic Melanoma Patients.

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    Serum lactate dehydrogenase (LDH) is a standard prognostic biomarker for stage IV melanoma patients. Often, LDH levels do not provide real-time information about the metastatic melanoma patients\u27 disease status and treatment response. Therefore, there is a need to find reliable blood biomarkers for improved monitoring of metastatic melanoma patients who are undergoing checkpoint inhibitor immunotherapy (CII). The objective in this prospective pilot study was to discover circulating cell-free microRNA (cfmiR) signatures in the plasma that could assess melanoma patients\u27 responses during CII. The cfmiRs were evaluated by the next-generation sequencing (NGS) HTG EdgeSeq microRNA (miR) Whole Transcriptome Assay (WTA; 2083 miRs) in 158 plasma samples obtained before and during the course of CII from 47 AJCC stage III/IV melanoma patients\u27 and 73 normal donors\u27 plasma samples. Initially, cfmiR profiles for pre- and post-treatment plasma samples of stage IV non-responder melanoma patients were compared to normal donors\u27 plasma samples. Using machine learning, we identified a 9 cfmiR signature that was associated with stage IV melanoma patients being non-responsive to CII. These cfmiRs were compared in pre- and post-treatment plasma samples from stage IV melanoma patients that showed good responses. Circulating miR-4649-3p, miR-615-3p, and miR-1234-3p demonstrated potential prognostic utility in assessing CII responses. Compared to LDH levels during CII, circulating miR-615-3p levels were consistently more efficient in detecting melanoma patients undergoing CII who developed progressive disease. By combining stage III/IV patients, 92 and 17 differentially expressed cfmiRs were identified in pre-treatment plasma samples from responder and non-responder patients, respectively. In conclusion, this pilot study demonstrated cfmiRs that identified treatment responses and could allow for real-time monitoring of patients receiving CII

    Sound Affects

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    IN A CITY OVERFLOWING WITH SOUND, NOISE AND RUCKUS, WHAT CAN WE LEARN? In this multimedia, multi-story project, we explore sound in New York City. We learn what New York City can tell us about sound, and what sound can tell us about New York City
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