Prevalence and Predictors of Household Food Insecurity among Adult/Youth Dyads at the Initiation of the iCook 4-H Two-Year Obesity Prevention Study

Objective: Determine food insecurity prevalence and predictors among adult/youth dyads enrolled in a childhood obesity prevention study (iCook 4-H).Methods: The iCook 4-H intervention was designed for youth (9-10 years old) and their adult main meals preparer to cook, eat, and play together. Although not an inclusion criteria, diverse, low income, and/or rural families were the target during recruitment. At baseline, adults completed surveys on food insecurity, socioeconomic and demographic characteristics and youth anthropometrics were collected with body mass index (BMI) calculated. Descriptive statistics were computed and chi-square analysis was conducted to test differences between potential predictors and food insecurity. Binomial logistic regression was used to assess the relationship between food insecurity and its predictors.Results: Thirty-four percent of households (n=71 of 206) were food insecure. Youth were primarily white (69.9%) and normal weight (58.3%). Adults were also primarily white (74.8%), overweight or obese (67.9%), married (68.9%), not participating in government assistance programs (57.8%), and held no college degree (55.3%). Based on the logistic regression model, households with a non-white youth (OR=13.53; 95% CI=3.33, 55.05), an adult without a college degree (OR=5.62; 95% CI=2.01, 15.73), and government assistance program participation (OR=5.63; 95% CI=2.63, 12.07) were significantly associated with household food insecurity. However, there was no significant association with BMI found (youth p=0.167; adult p=0.179).Conclusion: Consistent with previous findings, household food insecurity status was associated with youth race, adult education, and government assistance program participation. In contrast, no relationship between BMI and food insecurity status was observed in this study, which warrants further investigation

Shear viscosity of a crosslinked polymer melt

We investigate the static shear viscosity on the sol side of the vulcanization transition within a minimal mesoscopic model for the Rouse-dynamics of a randomly crosslinked melt of phantom polymers. We derive an exact relation between the viscosity and the resistances measured in a corresponding random resistor network. This enables us to calculate the viscosity exactly for an ensemble of crosslinks without correlations. The viscosity diverges logarithmically as the critical point is approached. For a more realistic ensemble of crosslinks amenable to the scaling description of percolation, we prove the scaling relation $k=\phi-\beta$ between the critical exponent $k$ of the viscosity, the thermal exponent $\beta$ associated with the gel fraction and the crossover exponent $\phi$ of a random resistor network.Comment: 8 pages, uses Europhysics Letters style; Revisions: results extende

Force-Extension Relation and Plateau Modulus for Wormlike Chains

We derive the linear force-extension relation for a wormlike chain of arbitrary stiffness including entropy elasticity, bending and thermodynamic buckling. From this we infer the plateau modulus $G^0$ of an isotropic entangled solution of wormlike chains. The entanglement length $L_e$ is expressed in terms of the characteristic network parameters for three different scaling regimes in the entangled phase. The entanglement transition and the concentration dependence of $G^0$ are analyzed. Finally we compare our findings with experimental data.Comment: 5 pages, 1 eps-figure, to appear in PR

Prospectus, September 16, 1987

https://spark.parkland.edu/prospectus_1987/1018/thumbnail.jp

Therapeutic Monoclonal Antibodies to Prevent Tuberculosis Infection

Mycobacteria tuberculosis (Mtb) is a major cause of human morbidity and mortality. Transmission occurs through inhalation of aerosolized Mtb and the initial infection is believed to occur primarily in the alveolar macrophage, although Mtb can infect other cells residing in the lung including dendritic cells, pneumocytes and M cells. Several molecules derived from Mtb are involved in the attachment of the organism to host receptors (opsonic and non-opsonic), which have been reasonably well elucidated. However, a complete understanding of how Mtb attaches to the host and the relative importance of each mechanism on the outcome of infection remains elusive. We hypothesize that protection from infection is possible by blocking the critical initial surface interactions of the organism with the host cell using specific monoclonal antibodies (mAbs). To develop effective mAbs, the outermost layers of Mtb, the capsule and outer membrane, were isolated and characterized by protein gel and LC/MS/MS. Approximately 1000 different proteins were identified in the isolations, of which ~25% were unique to one of the two fractions. The capsule or outer membrane preparations were used as antigens to immunize CD1 mice for up to 12 weeks to generate antibodies via traditional hybridoma generation. Antibodies were screened, selected and characterized by their ability to bind whole cell Mtb by ELISA, demonstration of unique heavy chain variable region sequence and binding specificity by Western Blot. Of approximately 1500 screened hybridomas, 30 lead mAbs have been isolated with specificity to various targets. Preliminary results suggest several of the lead mAb candidates are able to prevent Mtb-induced macrophage cell death in vitro. Future studies will attempt to confirm efficacy in vivo after aerosolized infection in mice with mAb-coated Mtb or parenteral administration of mAb(s). Targets of functional mAbs will be determined and these antigens could serve as viable candidates for vaccine development

Critical behaviour of the Rouse model for gelling polymers

It is shown that the traditionally accepted "Rouse values" for the critical exponents at the gelation transition do not arise from the Rouse model for gelling polymers. The true critical behaviour of the Rouse model for gelling polymers is obtained from spectral properties of the connectivity matrix of the fractal clusters that are formed by the molecules. The required spectral properties are related to the return probability of a "blind ant"-random walk on the critical percolating cluster. The resulting scaling relations express the critical exponents of the shear-stress-relaxation function, and hence those of the shear viscosity and of the first normal stress coefficient, in terms of the spectral dimension $d_{s}$ of the critical percolating cluster and the exponents $\sigma$ and $\tau$ of the cluster-size distribution.Comment: 9 pages, slightly extended version, to appear in J. Phys.

Screening of Hydrodynamic Interactions in Semidilute Polymer Solutions: A Computer Simulation Study

We study single-chain motion in semidilute solutions of polymers of length N = 1000 with excluded-volume and hydrodynamic interactions by a novel algorithm. The crossover length of the transition from Zimm (short lengths and times) to Rouse dynamics (larger scales) is proportional to the static screening length. The crossover time is the corresponding Zimm time. Our data indicate Zimm behavior at large lengths but short times. There is no hydrodynamic screening until the chains feel constraints, after which they resist the flow: "Incomplete screening" occurs in the time domain.Comment: 3 figure

The Prospect of Detecting Volcanic Signatures on an ExoEarth Using Direct Imaging

The James Webb Space Telescope (JWST) has provided the first opportunity to study the atmospheres of terrestrial exoplanets and estimate their surface conditions. Earth-sized planets around Sun-like stars are currently inaccessible with JWST however, and will have to be observed using the next generation of telescopes with direct imaging capabilities. Detecting active volcanism on an Earth-like planet would be particularly valuable as it would provide insight into its interior, and provide context for the commonality of the interior states of Earth and Venus. In this work we used a climate model to simulate four exoEarths over eight years with ongoing large igneous province eruptions with outputs ranging from 1.8-60 Gt of sulfur dioxide. The atmospheric data from the simulations were used to model direct imaging observations between 0.2-2.0 $\mu$m, producing reflectance spectra for every month of each exoEarth simulation. We calculated the amount of observation time required to detect each of the major absorption features in the spectra, and identified the most prominent effects that volcanism had on the reflectance spectra. These effects include changes in the size of the O$_3$, O$_2$, and H$_2$O absorption features, and changes in the slope of the spectrum. Of these changes, we conclude that the most detectable and least ambiguous evidence of volcanism are changes in both O$_3$ absorption and the slope of the spectrum.Comment: 13 pages, 5 figures, 4 tables, Accepted for publication in AJ (September 26, 2023