Development of interconnected silicon micro-evaporators for the on-detector electronics cooling of the future ITS detector in the ALICE experiment at LHC

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.The design of the future High Energy Physics (HEP) particle detectors for the upgrade of the LHC (Large Hadron Collider) experiments at CERN (European Organization for Nuclear Research) is pushing technological frontiers to the limit trying to reach unprecedented accuracy in particles identification and particle production dynamics in ultra-relativistic hadron collisions. The thermal management of the on-detector electronics and the development of low mass integrated cooling systems have become a crucial task in the design of silicon tracking detectors for HEP applications. In this paper, we present a novel concept of low mass interconnected silicon microchannel devices for the future Inner Tracking System of the ALICE (A Large Ion Collider Experiment) detector at LHC. This innovative design achieves the requirements of the detector while minimizing the total material budget

Infrastructure Wi-Fi for connected autonomous vehicle positioning : a review of the state-of-the-art

In order to realize intelligent vehicular transport networks and self driving cars, connected autonomous vehicles (CAVs) are required to be able to estimate their position to the nearest centimeter. Traditional positioning in CAVs is realized by using a global navigation satellite system (GNSS) such as global positioning system (GPS) or by fusing weighted location parameters from a GNSS with an inertial navigation systems (INSs). In urban environments where Wi-Fi coverage is ubiquitous and GNSS signals experience signal blockage, multipath or non line-of-sight (NLOS) propagation, enterprise or carrier-grade Wi-Fi networks can be opportunistically used for localization or “fused” with GNSS to improve the localization accuracy and precision. While GNSS-free localization systems are in the literature, a survey of vehicle localization from the perspective of a Wi-Fi anchor/infrastructure is limited. Consequently, this review seeks to investigate recent technological advances relating to positioning techniques between an ego vehicle and a vehicular network infrastructure. Also discussed in this paper is an analysis of the location accuracy, complexity and applicability of surveyed literature with respect to intelligent transportation system requirements for CAVs. It is envisaged that hybrid vehicular localization systems will enable pervasive localization services for CAVs as they travel through urban canyons, dense foliage or multi-story car parks

Extensive degeneracy, Coulomb phase and magnetic monopoles in an artificial realization of the square ice model

Artificial spin ice systems have been introduced as a possible mean to investigate frustration effects in a well-controlled manner by fabricating lithographically-patterned two-dimensional arrangements of interacting magnetic nanostructures. This approach offers the opportunity to visualize unconventional states of matter, directly in real space, and triggered a wealth of studies at the frontier between nanomagnetism, statistical thermodynamics and condensed matter physics. Despite the strong efforts made these last ten years to provide an artificial realization of the celebrated square ice model, no simple geometry based on arrays of nanomagnets succeeded to capture the macroscopically degenerate ground state manifold of the corresponding model. Instead, in all works reported so far, square lattices of nanomagnets are characterized by a magnetically ordered ground state consisting of local flux-closure configurations with alternating chirality. Here, we show experimentally and theoretically, that all the characteristics of the square ice model can be observed if the artificial square lattice is properly designed. The spin configurations we image after demagnetizing our arrays reveal unambiguous signatures of an algebraic spin liquid state characterized by the presence of pinch points in the associated magnetic structure factor. Local excitations, i.e. classical analogues of magnetic monopoles, are found to be free to evolve in a massively degenerated, divergence-free vacuum. We thus provide the first lab-on-chip platform allowing the investigation of collective phenomena, including Coulomb phases and ice-like physics.Comment: 26 pages, 10 figure

Intelligence within BAOR and NATO's Northern Army Group

During the Cold War the UK's principal military role was its commitment to the North Atlantic Treaty Organisation (NATO) through the British Army of the Rhine (BAOR), together with wartime command of NATO's Northern Army Group. The possibility of a surprise attack by the numerically superior Warsaw Pact forces ensured that great importance was attached to intelligence, warning and rapid mobilisation. As yet we know very little about the intelligence dimension of BAOR and its interface with NATO allies. This article attempts to address these neglected issues, ending with the impact of the 1973 Yom Kippur War upon NATO thinking about warning and surprise in the mid-1970s. It concludes that the arrangements made by Whitehall for support to BAOR from national assets during crisis or transition to war were - at best - improbable. Accordingly, over the years, BAOR developed its own unique assets in the realm of both intelligence collection and special operations in order to prepare for the possible outbreak of conflict

Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty

A randomised trial of 367 patients with acute myocardial infarction was performed to determine whether an invasive strategy combining thrombolysis with recombinant tissue-type plasminogen activator (rTPA), heparin, and acetylsalicylic acid, and immediate percutaneous transluminal coronary angioplasty (PTCA) would be superior to a noninvasive strategy with the same medical treatment but without immediate angiography and PTCA. Intravenous infusion of 100 mg rTPA was started within 5 h after onset of symptoms (median 156 min). Angiography was performed 6-165 min later in 180 out of 183 patients allocated to the invasive strategy; 184 patients were allocated to the non-invasive strategy. Immediate PTCA reduced the percentage stenosis of the infarc

Optimization of hybrid sol-gel coating for dropwise condensation of pure steam

We developed hybrid organic-inorganic sol-gel silica coatings with good durability in harsh environment (high temperatures, high vapor velocities) and with slightly hydrophobic behavior, sufficient to promote dropwise condensation (DWC) of pure steam. DWC is a very promising mechanism in new trends of thermal management and power generation systems to enhance the heat transfer during condensation as compared to film-wise condensation (FWC). The sol-gel coatings have been prepared from methyl triethoxy silane (MTES) and tetraethyl-orthosilicate (TEOS) and deposited on an aluminum substrate. The coatings were optimized in terms of precursor ratio and annealing temperature highlighting potentials and limits of such mixtures. A comprehensive surface characterization before and after saturated steam condensation tests has been performed and related to the thermal measurements for evaluating the heat transfer augmentation as compared to FWC obtained on untreated aluminum surfaces. The results showed that the developed hybrid organic-inorganic sol-gel silica coatings are promising DWC promoters

Effects of a 3-Week In-Hospital Body Weight Reduction Program on Cardiovascular Risk Factors, Muscle Performance, and Fatigue : A Retrospective Study in a Population of Obese Adults with or without Metabolic Syndrome

Background: In clinical practice, there is the diffuse conviction that obese subjects with metabolic syndrome may be more difficult to treat. Objectives and methods: The aim of the present study was that to investigate the effectiveness of a 3-week in-hospital body weight reduction program (BWRP) in a large population of obese subjects with and without metabolic syndrome (n = 1922; 222 men and 1700 women, age range 18-83 yr). Outcomes such as body mass index (BMI), total (TOT) and HDL cholesterol, systolic and diastolic blood pressures (SBP and DBP, respectively), coronary heart disease (CHD) score, fatigue severity score (FSS), and stair climbing test (SCT) time were evaluated before and after the intervention (\u394). A sex-, BMI-, and age-related stratification of the obese population with or without metabolic syndrome was applied. Results: When compared to obese subjects without metabolic syndrome, at the basal conditions, obese subjects had a poorer cardiometabolic profile, as demonstrated by higher triglycerides, TOT-cholesterol, DBP, SBP, and CHD score, and a more compromised muscle performance (evaluated by SCT), associated with more perception of fatigue (measured by FSS). Nevertheless, obese subjects with metabolic syndrome obtained more benefits from BWRP than those without metabolic syndrome for some outcomes (i.e., \u394TOT-cholesterol, \u394SBP, and \u394CHD score). Despite these differences, the BWRP-induced weight loss was similar between the two groups (i.e., \u394BMI) as well as the gain of muscle performance (i.e., \u394SCT) and the reduction of fatigue (i.e., \u394FSS). Interestingly, the potentially deleterious fall in HDL-cholesterol levels after BWRP was less evident in obese subjects with metabolic syndrome than those without metabolic syndrome. When pooling all data, the \u394CHD score was associated with age, sex, and metabolic syndrome. The remaining outcomes, such as \u394BMI, \u394FSS, and \u394SCT time, were associated with sex and age but not with metabolic syndrome. Finally, \u394BMI was positively correlated with \u394CHD score, \u394FSS, and \u394SCT time in both obese subjects without metabolic syndrome and obese subjects with metabolic syndrome. Conclusions: When comparing obese subjects undergoing a BWRP, metabolic syndrome is not a negative predictive factor affecting the effectiveness of this intervention in terms of weight loss, muscle performance, and psychological well-being

Factors associated with treatment of women with osteoporosis or osteopenia from a national survey

<p>Abstract</p> <p>Background</p> <p>Health outcomes could be improved if women at high risk for osteoporotic fracture were matched to effective treatment. This study determined the extent to which treatment for osteoporosis/osteopenia corresponded to the presence of specific risk factors for osteoporotic fracture.</p> <p>Methods</p> <p>This retrospective analysis of the United States 2007 National Health and Wellness Survey included women age ≥ 40 years who reported having a diagnosis of osteoporosis (69% of 3276) or osteopenia (31% of 3276). Patients were stratified by whether they were or were not taking prescription treatment for osteoporosis/osteopenia. Using 34 patient characteristics as covariates, logistic regression was used to determine factors associated with treatment.</p> <p>Results</p> <p>Current prescription treatment was reported by 1800 of 3276 (54.9%) women with osteoporosis/osteopenia. The following factors were associated with receiving prescription treatment: patient-reported diagnosis of osteoporosis (versus osteopenia); previous bone mineral density test; ≥ 2 fractures since age 50; older age; lower body mass index; better physical functioning; postmenopausal status; family history of osteoporosis; fewer comorbidities; prescription insurance coverage; higher total prescription count; higher ratio of prescription costs to monthly income; higher income; single status; previous visit to a rheumatologist or gynecologist; and 1 or 2 outpatient visits to healthcare provider (vs. none) in the prior 6 months. Glucocorticoid, tobacco, and daily alcohol use were risk factors for fracture that were not associated with treatment.</p> <p>Conclusions</p> <p>There is a mismatch between those women who could benefit from treatment for osteoporosis and those who are actually treated. For example, self-reported use of glucocorticoids, tobacco, and alcohol were not associated with prescription treatment of osteoporosis. Other clinical and socioeconomic factors were associated with treatment (e.g. prescription drug coverage and higher income) or not (e.g. comorbid osteoarthritis and anxiety) and could be opportunities to improve care.</p

GNSS Vulnerabilities and Existing Solutions:A Review of the Literature

This literature review paper focuses on existing vulnerabilities associated with global navigation satellite systems (GNSSs). With respect to the civilian/non encrypted GNSSs, they are employed for proving positioning, navigation and timing (PNT) solutions across a wide range of industries. Some of these include electric power grids, stock exchange systems, cellular communications, agriculture, unmanned aerial systems and intelligent transportation systems. In this survey paper, physical degradations, existing threats and solutions adopted in academia and industry are presented. In regards to GNSS threats, jamming and spoofing attacks as well as detection techniques adopted in the literature are surveyed and summarized. Also discussed are multipath propagation in GNSS and non line-of-sight (NLoS) detection techniques. The review also identifies and discusses open research areas and techniques which can be investigated for the purpose of enhancing the robustness of GNSS