220 research outputs found
Hubungan Motivasi Berprestasi, Prilaku Kepemimpinan Kepala Sekolah Dan Etos Kerja Dengan Kinerja Guru Di SMA N 1 Kubutambahan
This study aimed to determine: (1) the relationship between achievement motivation with teacher performance in SMA N 1 Kubutambahan, (2) the relationship between principal leadership behaviors with teacher performance in SMA N 1 Kubutambahan, (3) the relationship between the performance of the teachers work ethic in SMA N 1 Kubutambahan, (4) simultaneous relationship between achievement motivation, school leadership and work ethic with the performance of teachers in SMA N 1 Kubutambahan. This study was designed with a correlational design ex-post facto by using a quantitative approach.The study population was all teachers in SMA N 1 Kubutambahan. The sample retrieval technique using census study with the number 47. Data were collected by questionnaires. Data were analyzed by multiple regression and partial analysis. The results showed that: (1) there is a significant contribution to the achievement motivation with teacher performance through the regression equation Y = 95.582 + 0.669 X1 (p <0.05) with a contribution of 44.6% and the effective contribution of 18.26%, (2) there is a significant contribution between principal leadership behaviors with teacher performance through the regression equation Y = 91.918 + 0.705 X2 (p <0.05) with a contribution of 59.7% and the effective contribution of 35.95%, (3) there is a significant contribution to the work ethos of teacher performance through the regression equation Y = 83.236 + 0.762 X3 (p <0.05) with a contribution of 41.9% and the effective contribution of 18.07%, (4) there is a significant contribution between achievement motivation, school leadership behavior, and work ethos simultaneously with the performance of teachers of SMAN I Kubutambahan. through the regression equation Y = 55.794 + 0.274 X1 + 0.425 X2 + 0.328 X3 (p <0.05) with a contribution of 72.3%
The role played by the molecular weight and acetylation degree in modualting the stiffness and elasticity of chitosan gels
A broad library of chitosans was produced varying the molecular weight and the fraction of acetylated units, FA. The produced chitosans were used for the formation of wall-to-wall cylindrical gels through a controlled external gelation using tripolyphosphate (TPP) as cross-linker. The resulting gels were analyzed by rheometry. Viscosity average degree of polymerization (DPv\uaf)\u202f>\u202f152 was shown to be required for the formation of stable gels. Both gel stiffness and gel rupture strength were proportional to the molecular weight regardless of the applied deformation. Increasing acetylation produced a marked reduction of the shear modulus, but, in parallel, switched the networks from rigid and brittle to weak and elastic. Intriguingly, gels made of chitosan with FA\u202f=\u202f0.37 displayed notable elasticity, i.e. up to 90% of applied strain falls into linear regime. These findings suggest that the frequency of glucosamine (D unit) and N-acetyl-glucosamine (A unit) contribute to a subtle structure-property relationship in chitosan-TPP gels
Perancangan Audio Visual Seni Bantengan Di Kota Batu
Seni Bantengan adalah seni tradisional Jawa Timur yang banyak ditemukan di Kota Batu, Malang. Masih banyak masyarakat di dalam maupun di luar Malang Raya yang belum mengenal seni ini. Padahal jika dikenalkan dan dipromosikan dengan baik, seni Bantengan bisa berpotensi menjadi wisata budaya Kota Batu. Tujuan dari perancangan ini adalah untuk memperkenalkan dan memberikan informasi kepada masyarakat Indonesia akan seni Bantengan melalui video ilustrasi 2D. Dengan menggunakan teknik ilustrasi, efek paralaks, dan efek gerak grafis, serta penyebaran yang dilakukan melalui media sosial dan website, maka informasi mengenai seni ini bisa disampaikan dan dikenalkan dengan lebih menarik dan efektif
N-isopropyl chitosan. A pH- and thermo-responsive polysaccharide for gel formation
The present contribution deals with the synthesis and characterization of N-isopropyl chitosan in which the introduction of hydrophobic groups leads to an increased flexibility of the polysaccharide backbone. The isopropyl groups extend the solubility of the modified-chitosan samples and render the modified chitosan a pH- and thermo-sensitive system for hydrogel formation. Indeed, upon varying the pH of the system and/or its temperature within a range compatible with biological applications, a non-reversible sol-gel transition occurs, as determined through extended rheological analyses. The modified chitosan samples show a very good biocompatibility as determined through preliminary viability and cell growth experiments
Temporary/Permanent Dual Cross-Link Gels Formed of a Bioactive Lactose-Modified Chitosan
Mounting evidences have recognized that dual cross-link and double-network gels can promisingly recapitulate the complex living tissue architecture and overcome mechanical limitations of conventional scaffolds used hitherto in regenerative medicine. Here, dual cross-link gels formed of a bioactive lactose-modified chitosan reticulated via both temporary (boric acid-based) and permanent (genipin-based) cross-linkers are reported. While boric acid rapidly binds to lactitol flanking diols increasing the overall viscosity, a slow temperature-driven genipin binding process takes place allowing for network strengthening. Combination of frequency and stress sweep experiments in the linear stress\u2013strain region shows that ultimate gel strength, toughness, and viscoelasticity depend on polymer-to-genipin molar ratio. Notably, herewith it is demonstrated that linear stretching correlates with strain energy dissipation through boric acid binding/unbinding dynamics. Strain-hardening effect in the nonlinear regime, along with good biocompatibility in vitro, points at an interesting role of present system as biological extracellular matrix substitute
Myoblast adhesion, proliferation and differentiation on Human Elastin-Like Polypeptide (HELP) hydrogels
Purpose: The biochemical, mechanical and topographic properties of extracellular matrix are crucially involved in determining skeletal muscle cells morphogenesis, proliferation and differentiation. Human elastin-like polypeptides (HELPs) are recombinant biomimetic proteins designed to mimicking some properties of the native matrix protein; when employed as myoblasts adhesion substrates they stimulate in vitro myogenesis. Given the consequences that biophysical properties of extracellular matrix exert on skeletal muscle cells, the aim of this work was to investigate the effects of HELP hydrogels on myoblasts viability and functions.
Methods: We recently synthesized a novel polypeptide, HELPc, by fusing the elastin-like backbone to a 41aa stretch present in the α2 chain of type IV collagen, containing two RGD motifs. To obtain hydrogels, the enzymatic cross-linking of the HELPc was accomplished by transglutaminase. Here, we employed both non cross-linked HELPc glass coatings and cross-linked HELPc hydrogels at different monomer density as adhesion substrates for C2C12 cells, used as myoblasts model.
Results: By comparing cell adhesion, proliferation and differentiation, we revealed several striking differences. Depending on support rigidity, adhesion to HELPc substrates dictates cell morphology, spreading, focal adhesions formation and cytoskeletal organization. Hydrogels greatly stimulated cell proliferation, particularly in low serum-medium, and partially inhibited myogenic differentiation.
Conclusions: In the whole, the results underline the potentiality of these genetically engineered polypeptides as a tool for dissecting crucial steps in myogenesis
Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru.
The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses for a cohort of patients with lymphadenopathy of unknown etiology. 121 Peruvian adults with lymphadenopathy underwent lymph node biopsy for microbiological and histopathological evaluation. Mean patient age was 41 years (Interquartile Range 26-52), 56% were males, and 39% were HIV positive. Patients reported fever (31%), weight loss (23%), and headache (22%); HIV infection was associated with fever (P < 0.05) and gastrointestinal symptoms (P < 0.05). Abnormalities were reported in 40% of chest X-rays (N = 101). Physicians suspected TB in 92 patients (76%), lymphoma in 19 patients (16%), and other malignancy in seven patients (5.8%). Histological diagnoses (N = 117) included tuberculosis (34%), hyperplasia (27%), lymphoma (13%), and nonlymphoma malignancy (14%). Hyperplasia was more common (P < 0.001) and lymphoma less common (P = 0.005) among HIV-positive than HIV-negative patients. There was a trend toward reduced frequency of caseous necrosis in samples from HIV-positive than HIV-negative TB patients (67 versus 93%, P = 0.055). The spectrum of diagnoses was broad, and clinical and radiological features correlated poorly with diagnosis. On the basis of clinical features, physicians over-diagnosed TB, and under-diagnosed malignancy. Although this may not be inappropriate in resource-limited settings where TB is the most frequent easily treatable cause of lymphadenopathy, diagnostic delays can be detrimental to patients with malignancy. It is important that patients with lymphadenopathy undergo a full diagnostic work-up including sampling for histological evaluation to obtain an accurate diagnosis
- …