1,930 research outputs found
Psoriatic Arthritis and Diabetes: A Population-Based Cross-Sectional Study
Background. Diabetes has been associated with psoriasis, but little is known about the association between psoriatic arthritis and diabetes. Methods. Patients diagnosed with psoriatic arthritis by a rheumatologist were compared to age- and sex-matched patients without psoriatic arthritis regarding the prevalence of diabetes in a population-based cross-sectional study using logistic multivariate models. The study was performed utilizing the medical database of Clalit, the largest healthcare provider organization in Israel. Results. The study included 549 patients with psoriatic arthritis ≥21 years and 1,098 patients without psoriatic arthritis. The prevalence of diabetes in patients with psoriatic arthritis was increased as compared to the prevalence in patients without psoriatic arthritis (15.3% versus 10.7%, value = 0.008). The difference was prominent among females (18.7% versus 10.3%, ) but not among males (11.2% in patients with and without psoriatic arthritis, ). In a multivariate analysis, psoriatic arthritis was associated with diabetes among females (OR = 1.60, 95% CI: 1.02–2.52, ) but not among males (OR = 0.71, 95% CI: 0.42–1.22, ). Conclusion. Our study suggests a possible association between psoriatic arthritis and diabetes in women. Women with psoriatic arthritis might be candidates for diabetes screening
Aggregation Patterns in Stressed Bacteria
We study the formation of spot patterns seen in a variety of bacterial
species when the bacteria are subjected to oxidative stress due to hazardous
byproducts of respiration. Our approach consists of coupling the cell density
field to a chemoattractant concentration as well as to nutrient and waste
fields. The latter serves as a triggering field for emission of
chemoattractant. Important elements in the proposed model include the
propagation of a front of motile bacteria radially outward form an initial
site, a Turing instability of the uniformly dense state and a reduction of
motility for cells sufficiently far behind the front. The wide variety of
patterns seen in the experiments is explained as being due the variation of the
details of the initiation of the chemoattractant emission as well as the
transition to a non-motile phase.Comment: 4 pages, REVTeX with 4 postscript figures (uuencoded) Figures 1a and
1b are available from the authors; paper submitted to PRL
Orthogonality Catastrophe in Parametric Random Matrices
We study the orthogonality catastrophe due to a parametric change of the
single-particle (mean field) Hamiltonian of an ergodic system. The Hamiltonian
is modeled by a suitable random matrix ensemble. We show that the overlap
between the original and the parametrically modified many-body ground states,
, taken as Slater determinants, decreases like , where is
the number of electrons in the systems, is a numerical constant of the
order of one, and is the deformation measured in units of the typical
distance between anticrossings. We show that the statistical fluctuations of
are largely due to properties of the levels near the Fermi energy.Comment: 12 pages, 8 figure
Novel type of phase transition in a system of self-driven particles
A simple model with a novel type of dynamics is introduced in order to
investigate the emergence of self-ordered motion in systems of particles with
biologically motivated interaction. In our model particles are driven with a
constant absolute velocity and at each time step assume the average direction
of motion of the particles in their neighborhood with some random perturbation
() added. We present numerical evidence that this model results in a
kinetic phase transition from no transport (zero average velocity, ) to finite net transport through spontaneous symmetry breaking of the
rotational symmetry. The transition is continuous since is
found to scale as with
Stability of the Black Hole Horizon and the Landau Ghost
The stability of the black hole horizon is demanded by both cosmic censorship
and the generalized second law of thermodynamics. We test the consistency of
these principles by attempting to exceed the black hole extremality condition
in various process in which a U(1) charge is added to a nearly extreme
Reissner--Nordstr\"om black hole charged with a {\it different\/} type of U(1)
charge. For an infalling spherical charged shell the attempt is foiled by the
self--Coulomb repulsion of the shell. For an infalling classical charge it
fails because the required classical charge radius exceeds the size of the
black hole. For a quantum charge the horizon is saved because in order to avoid
the Landau ghost, the effective coupling constant cannot be large enough to
accomplish the removal.Comment: 12 pages, RevTe
Human Time-Frequency Acuity Beats the Fourier Uncertainty Principle
The time-frequency uncertainty principle states that the product of the
temporal and frequency extents of a signal cannot be smaller than .
We study human ability to simultaneously judge the frequency and the timing of
a sound. Our subjects often exceeded the uncertainty limit, sometimes by more
than tenfold, mostly through remarkable timing acuity. Our results establish a
lower bound for the nonlinearity and complexity of the algorithms employed by
our brains in parsing transient sounds, rule out simple "linear filter" models
of early auditory processing, and highlight timing acuity as a central feature
in auditory object processing.Comment: 4 pages, 2 figures; Accepted at PR
Lubricating Bacteria Model for Branching growth of Bacterial Colonies
Various bacterial strains (e.g. strains belonging to the genera Bacillus,
Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns
during growth on poor semi-solid substrates. These patterns reflect the
bacterial cooperative self-organization. Central part of the cooperation is the
collective formation of lubricant on top of the agar which enables the bacteria
to swim. Hence it provides the colony means to advance towards the food. One
method of modeling the colonial development is via coupled reaction-diffusion
equations which describe the time evolution of the bacterial density and the
concentrations of the relevant chemical fields. This idea has been pursued by a
number of groups. Here we present an additional model which specifically
includes an evolution equation for the lubricant excreted by the bacteria. We
show that when the diffusion of the fluid is governed by nonlinear diffusion
coefficient branching patterns evolves. We study the effect of the rates of
emission and decomposition of the lubricant fluid on the observed patterns. The
results are compared with experimental observations. We also include fields of
chemotactic agents and food chemotaxis and conclude that these features are
needed in order to explain the observations.Comment: 1 latex file, 16 jpeg files, submitted to Phys. Rev.
The Wyoming Survey for H-alpha. I. Initial Results at z ~ 0.16 and 0.24
The Wyoming Survey for H-alpha, or WySH, is a large-area, ground-based,
narrowband imaging survey for H-alpha-emitting galaxies over the latter half of
the age of the Universe. The survey spans several square degrees in a set of
fields of low Galactic cirrus emission. The observing program focuses on
multiple dz~0.02 epochs from z~0.16 to z~0.81 down to a uniform
(continuum+line) luminosity at each epoch of ~10^33 W uncorrected for
extinction (3sigma for a 3" diameter aperture). First results are presented
here for 98+208 galaxies observed over approximately 2 square degrees at
redshifts z~0.16 and 0.24, including preliminary luminosity functions at these
two epochs. These data clearly show an evolution with lookback time in the
volume-averaged cosmic star formation rate. Integrals of Schechter fits to the
extinction-corrected H-alpha luminosity functions indicate star formation rates
per co-moving volume of 0.009 and 0.014 h_70 M_sun/yr/Mpc^3 at z~0.16 and 0.24,
respectively. The formal uncertainties in the Schechter fits, based on this
initial subset of the survey, correspond to uncertainties in the cosmic star
formation rate density at the >~40% level; the tentative uncertainty due to
cosmic variance is 25%, estimated from separately carrying out the analysis on
data from the first two fields with substantial datasets.Comment: To appear in the Astronomical Journa
The Relational Bottleneck as an Inductive Bias for Efficient Abstraction
A central challenge for cognitive science is to explain how abstract concepts
are acquired from limited experience. This effort has often been framed in
terms of a dichotomy between empiricist and nativist approaches, most recently
embodied by debates concerning deep neural networks and symbolic cognitive
models. Here, we highlight a recently emerging line of work that suggests a
novel reconciliation of these approaches, by exploiting an inductive bias that
we term the relational bottleneck. We review a family of models that employ
this approach to induce abstractions in a data-efficient manner, emphasizing
their potential as candidate models for the acquisition of abstract concepts in
the human mind and brain
Nonattendance in pediatric pulmonary clinics: an ambulatory survey
<p>Abstract</p> <p>Background</p> <p>Nonattendance for scheduled appointments disturbs the effective management of pediatric pulmonary clinics. We hypothesized that the reasons for non-attendance and the necessary solutions might be different in pediatric pulmonary medicine than in other pediatric fields. We therefore investigated the factors associated with nonattendance this field in order to devise a corrective strategy.</p> <p>Methods</p> <p>The effect of age, gender, ethnic origin, waiting time for an appointment and the timing of appointments during the day on nonattendance proportion were assessed. Chi-square tests were used to analyze statistically significant differences of categorical variables. Logistic regression models were used for multivariate analysis.</p> <p>Results</p> <p>A total of 1190 pediatric pulmonology clinic visits in a 21 month period were included in the study. The overall proportion of nonattendance was 30.6%. Nonattendance was 23.8% when there was a short waiting time for an appointment (1–7 days) and 36.3% when there was a long waiting time (8 days and above) (p-value < 0.001). Nonattendance was 28.7% between 8 a.m. to 3 p.m. and 37.5% after 3 p.m. (p = 0.007). Jewish rural patients had 15.4% nonattendance, Jewish urban patients had 31.2% nonattendance and Bedouin patients had 32.9% nonattendance (p < 0.004). Age and gender were not significantly associated with nonattendance proportions. A multivariate logistic regression model demonstrated that the waiting time for an appointment, time of the day, and the patients' origin was significantly associated with nonattendance.</p> <p>Conclusion</p> <p>The factors associated with nonattendance in pediatric pulmonary clinics include the length of waiting time for an appointment, the hour of the appointment within the day and the origin of the patient.</p
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