8 research outputs found
Surprises in the Orbital Magnetic Moment and g-Factor of the Dynamic Jahn-Teller Ion C_{60}^-
We calculate the magnetic susceptibility and g-factor of the isolated
C_{60}^- ion at zero temperature, with a proper treatment of the dynamical
Jahn-Teller effect, and of the associated orbital angular momentum, Ham-reduced
gyromagnetic ratio, and molecular spin-orbit coupling. A number of surprises
emerge. First, the predicted molecular spin-orbit splitting is two orders of
magnitude smaller than in the bare carbon atom, due to the large radius of
curvature of the molecule. Second, this reduced spin-orbit splitting is
comparable to Zeeman energies, for instance, in X-band EPR at 3.39KGauss, and a
field dependence of the g-factor is predicted. Third, the orbital gyromagnetic
factor is strongly reduced by vibron coupling, and so therefore are the
effective weak-field g-factors of all low-lying states. In particular, the
ground-state doublet of C_{60}^- is predicted to show a negative g-factor of
\sim -0.1.Comment: 19 pages RevTex, 2 postscript figures include
Open-Label, phase 2 study of blinatumomab as second salvage therapy in adults with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma
The phase 2 portion of this open-label phase 2/3 study assessed the efficacy and safety of blinatumomab as second salvage for aggressive relapsed or refractory (r/r) aggressive B-cell non-Hodgkin lymphoma (B-NHL) following platinum-based first salvage chemotherapy. Forty-one patients with aggressive disease (32% relapsed; 68% refractory) enrolled and received stepwise blinatumomab (9\u201328\u2013112 \u3bcg/day) in a 70-day cycle 1 and an optional 28-day cycle 2; 19 (46%) completed cycle 1 and 3 (7%) completed cycle 2. The overall response rate after 12 weeks was 37%, including 9 (22%) complete metabolic responses. Eight (20%) patients (all responders) subsequently received stem cell transplants. Grade 653 adverse events were reported in 29 (71%) patients. Grade 3 cytokine release syndrome occurred in one patient. Grade 3 neurologic events occurred in 10 (24%) patients; all resolved. Blinatumomab monotherapy appears effective as second salvage therapy in patients with r/r aggressive B-NHL. Trial registration: NCT02910063
The decision to opt for abortion
Key message points
- Most women reach a decision to have an abortion rapidly.
- Most women have reached their decision before the consultation with the abortion provider.
- Certain women who have risk factors for post-abortion psychological reactions should be targeted and offered counselling.
- Pregnancy options counselling should not be mandatory.
- 'Cooling-off' periods lead to abortions at later gestation
Solving Unit Commitment Problem Using Multi-agent Evolutionary Programming Incorporating Priority List
Safe and Appropriate Use of lodinated Radiographic Contrast Agents: Is There a Reason to Use High-Osmolality lodinated Contrast Agents?
Currently cohabiting: relationship attitudes, expectations and outcomes
This study uses prospective data from the British Household Panel Survey to analyse individualsâ relationship expectations and subsequent outcomes between 1998 and 2005. How do relationship expectations differ by age, sex, previous relationship history and parenthood? How do attitudes towards cohabitation differ by age, sex, previous relationship history and parenthood? Prospective data are particularly well suited to answering these questions as the relationship expectations are collected whilst the subjective state exists, allowing systematic empirical investigation of social change