2,169 research outputs found

    9. Ecological Transition

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    The global climate emergency is the main concern of chapter 9, by D’Maris Coffman, Roberto Cardinale, Jing Meng and Zhifu Mi. Anthropogenic climate change is widely understood to be the greatest existential threat to human societies in the coming centuries. The Intergovernmental Panel on Climate Change (IPCC) was established in 1988 to coordinate a global response to the coming crisis. The IPCC’s publication of the Special Report on Global Warming of 1.5 °C (SR15) in October 2018 has helped to galvanize public opinion and has given rise to unprecedented climate activism. State actors now recognise a need for immediate action. Broadly speaking, possible responses to climate change fall into three categories: mitigation, adaptation and remediation. Mitigation means measures to reduce carbon and methane emissions or to enhance carbon sinks; adaptation means measures that ameliorate the effects of climate change on human populations; and remediation means intentional measures to counteract the effects of greenhouse gas (GHG) emissions, including global warming and ocean acidification. There are inevitable trade-offs between the costs of mitigation and those of adaptation over decadal time horizons. Nevertheless, with all three responses, large-scale infrastructure investment is required, with varying degrees of involvement by state actors, multilateral organizations, other non-governmental organizations (including religious groups) and, most significantly, private capital markets. In the current climate, multilateral development banks (MDBs) have taken a leading role. The EIB particularly is in the process of rebranding itself as a Climate Bank for Europe following Emmanuel Macron’s call. The authors then explore the investment opportunities that arise as a result of the growing urgency of the low carbon transition

    The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms

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    BACKGROUND: Runx genes encode proteins defined by the highly conserved Runt DNA-binding domain. Studies of Runx genes and proteins in model organisms indicate that they are key transcriptional regulators of animal development. However, little is known about Runx gene evolution. RESULTS: A phylogenetically broad sampling of publicly available Runx gene sequences was collected. In addition to the published sequences from mouse, sea urchin, Drosophila melanogaster and Caenorhabditis elegans, we collected several previously uncharacterised Runx sequences from public genome sequence databases. Among deuterostomes, mouse and pufferfish each contain three Runx genes, while the tunicate Ciona intestinalis and the sea urchin Strongylocentrotus purpuratus were each found to have only one Runx gene. Among protostomes, C. elegans has a single Runx gene, while Anopheles gambiae has three and D. melanogaster has four, including two genes that have not been previously described. Comparative sequence analysis reveals two highly conserved introns, one within and one just downstream of the Runt domain. All vertebrate Runx genes utilize two alternative promoters. CONCLUSIONS: In the current public sequence database, the Runt domain is found only in bilaterians, suggesting that it may be a metazoan invention. Bilaterians appear to ancestrally contain a single Runx gene, suggesting that the multiple Runx genes in vertebrates and insects arose by independent duplication events within those respective lineages. At least two introns were present in the primordial bilaterian Runx gene. Alternative promoter usage arose prior to the duplication events that gave rise to three Runx genes in vertebrates

    Allelism of ser (JBM5) and ser-3 on linkage group I

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    Allelism of ser (JBM5) and ser-3 on linkage group

    Constraint on teleportation over multipartite pure states

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    We first define a quantity exhibiting the usefulness of bipartite quantum states for teleportation, called the quantum teleportation capability, and then investigate its restricted shareability in multi-party quantum systems. In this work, we verify that the quantum teleportation capability has a monogamous property in its shareability for arbitrary three-qutrit pure states by employing the monogamy inequality in terms of the negativity.Comment: 4 pages, 1 figur

    Formal and finite order equivalences

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    We show that two families of germs of real-analytic subsets in CnC^{n} are formally equivalent if and only if they are equivalent of any finite order. We further apply the same technique to obtain analogous statements for equivalences of real-analytic self-maps and vector fields under conjugations. On the other hand, we provide an example of two sets of germs of smooth curves that are equivalent of any finite order but not formally equivalent

    Grain boundary energies and cohesive strength as a function of geometry

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    Cohesive laws are stress-strain curves used in finite element calculations to describe the debonding of interfaces such as grain boundaries. It would be convenient to describe grain boundary cohesive laws as a function of the parameters needed to describe the grain boundary geometry; two parameters in 2D and 5 parameters in 3D. However, we find that the cohesive law is not a smooth function of these parameters. In fact, it is discontinuous at geometries for which the two grains have repeat distances that are rational with respect to one another. Using atomistic simulations, we extract grain boundary energies and cohesive laws of grain boundary fracture in 2D with a Lennard-Jones potential for all possible geometries which can be simulated within periodic boundary conditions with a maximum box size. We introduce a model where grain boundaries are represented as high symmetry boundaries decorated by extra dislocations. Using it, we develop a functional form for the symmetric grain boundary energies, which have cusps at all high symmetry angles. We also find the asymptotic form of the fracture toughness near the discontinuities at high symmetry grain boundaries using our dislocation decoration model.Comment: 12 pages, 19 figures, changed titl

    Some entanglement features of three-atoms Tavis-Cummings model: Cooperative case

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    In this paper we consider a system of identical three two-level atoms interacting at resonance with a single-mode of the quantized field in a lossless cavity. The initial cavity field is prepared in the coherent state while the atoms are taken initially to be either in the uppermost excited state "∣eee>|eee>" or The GHZ\textmd{GHZ}-state or the W\textmd{W}-state. For this system we investigate different kinds of atomic inversion and entanglement, which arise between the different parts of the system due to the interaction. Also the relationship, between entanglement and some other nonclassical effects in the statistical properties, such as collapses and revivals in the atomic inversion where superharmonic effects appear, is discussed. The QQ-functions for different cases are discussed. Most remarkably it is found that the GHZ\textmd{GHZ}-state is more robust against energy losses, showing almost coherent trapping and Schr\"odinger-cat states can not be produced from such state. Also the entanglement of GHZ\textmd{GHZ}-state is more robust than the W\textmd{W}-state. Another interesting feature found is that the state which has no pairwise entanglement initially will have a much improvement of such pairwise entanglement through the evolution. Sudden death and sudden revival of atoms-pairwise entanglement are produced with the W\textmd{W}-state.Comment: 14 pages, 7 figure

    Experiences of Inpatient Bone Marrow Transplantation Nurses and Providers Using Electronic Symptom Reporting

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    Purpose To investigate the use of electronic patient-reported outcomes (PROs) to assess symptoms and how they can provide opportunities to clinicians to address symptoms in a timely manner to improve clinical care. As part of a larger study to evaluate whether providing standardized symptom reports to the medical team would decrease the time to treatment of reported symptoms in hematopoietic stem-cell transplant recipients, we assessed nurses’ and providers’ perceptions of electronic symptom reporting. Methods Semistructured interviews of RNs, MDs, NPs and PAs were conducted at an academic cancer center in the southeastern United States. Nurses’ and providers’ perceptions of electronic symptom reporting were explored. Interviews were audio-recorded, transcribed, and coded by two investigators to identify major themes. Results Fourteen RNs and seven providers (MDs, PAs, and NPs) participated in the interviews. Three main themes emerged from the interviews: electronic symptom reporting may improve assessment and care, integrating symptom reporting into nurse workflow presents difficulties, and there are barriers for completion of surveys. Conclusion The majority of nurses and providers believed that the inclusion of electronic symptom reporting in bone marrow transplantation inpatient units has the potential to improve care but that barriers to implementation remain
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