Ruptures and repairs of group therapy alliance. an untold story in psychotherapy research

Although previous studies investigated the characteristics of therapeutic alliance in group treatments, there is still a dearth of research on group alliance ruptures and repairs. The model by Safran and Muran was originally developed to address therapeutic alliance in individual therapies, and the usefulness of this approach to group intervention needs to be demonstrated. Alliance ruptures are possible at member to therapist, member to member, member to group levels. Moreover, repairs of ruptures in group are quite complex, i.e., because other group members have to process the rupture even if not directly involved. The aim of the current study is to review the empirical research on group alliance, and to examine whether the rupture repair model can be a suitable framework for clinical understanding and research of the complexity of therapeutic alliance in group treatments. We provide clinical vignettes and commentary to illustrate theoretical and research aspects of therapeutic alliance rupture and repair in groups. Our colleague Jeremy Safran made a substantial contribution to research on therapeutic alliance, and the current paper illustrates the enduring legacy of this work and its potential application to the group therapy context

Eye-movements reveal semantic interference effects during the encoding of naturalistic scenes in long-term memory

Similarity-based semantic interference (SI) hinders memory recognition. Within long-term visual memory paradigms, the more scenes (or objects) from the same semantic category are viewed, the harder it is to recognize each individual instance. A growing body of evidence shows that overt attention is intimately linked to memory. However, it is yet to be understood whether SI mediates overt attention during scene encoding, and so explain its detrimental impact on recognition memory. In the current experiment, participants watched 372 photographs belonging to different semantic categories (e.g., a kitchen) with different frequency (4, 20, 40 or 60 images), while being eye-tracked. After 10 minutes, they were presented with the same 372 photographs plus 372 new photographs and asked whether they recognized (or not) each photo (i.e., old/new paradigm). We found that the more the SI, the poorer the recognition performance, especially for old scenes of which memory representations existed. Scenes more widely explored were better recognized, but for increasing SI, participants focused on more local regions of the scene in search for its potentially distinctive details. Attending to the centre of the display, or to scene regions rich in low-level saliency was detrimental to recognition accuracy, and as SI increased participants were more likely to rely on visual saliency. The complexity of maintaining faithful memory representations for increasing SI also manifested in longer fixation durations; in fact, a more successful encoding was also associated with shorter fixations. Our study highlights the interdependence between attention and memory during high-level processing of semantic information

Unidimensional and Multidimensional Methods for Recurrence Quantification Analysis with crqa

Recurrence quantification analysis is a widely used method for characterizing patterns in time series. This article presents a comprehensive survey for conducting a wide range of recurrence based analyses to quantify the dynamical structure of single and multivariate time series and capture coupling properties underlying leader-follower relationships. The basics of recurrence quantification analysis (RQA) and all its variants are formally introduced step-by-step from the simplest auto recurrence to the most advanced multivariate case. Importantly, we show how such RQA methods can be deployed under a single computational framework in R using a substantially renewed version of our crqa 2.0 package. This package includes implementations of several recent advances in recurrence based analysis, among them applications to multivariate data and improved entropy calculations for categorical data. We show concrete applications of our package to example data, together with a detailed description of its functions and some guidelines on their usage

Dynamical changes of the polar cap potential structure: an information theory approach

Some features, such as vortex structures often observed through a wide spread of spatial scales, suggest that ionospheric convection is turbulent and complex in nature. Here, applying concepts from information theory and complex system physics, we firstly evaluate a pseudo Shannon entropy, <i>H</i>, associated with the polar cap potential obtained from the Super Dual Auroral Radar Network (SuperDARN) and, then, estimate the degree of disorder and the degree of complexity of ionospheric convection under different Interplanetary Magnetic Field (IMF) conditions. The aforementioned quantities are computed starting from time series of the coefficients of the 4th order spherical harmonics expansion of the polar cap potential for three periods, characterised by: (i) steady IMF <i>B<sub>z</sub></i> > 0, (ii) steady IMF <i>B<sub>z</sub></i> < 0 and (iii) a double rotation from negative to positive and then positive to negative <i>B<sub>z</sub></i>. A neat dynamical topological transition is observed when the IMF <i>B<sub>z</sub></i> turns from negative to positive and vice versa, pointing toward the possible occurrence of an order/disorder phase transition, which is the counterpart of the large scale convection rearrangement and of the increase of the global coherence. This result has been confirmed by applying the same analysis to a larger data base of about twenty days of SuperDARN data, allowing to investigate the role of IMF <i>B<sub>y</sub></i> too

Dynamical changes of the polar cap potential structure: an information theory approach

Abstract. Some features, such as vortex structures often observed through a wide spread of spatial scales, suggest that ionospheric convection is turbulent and complex in nature. Here, applying concepts from information theory and complex system physics, we firstly evaluate a pseudo Shannon entropy, H, associated with the polar cap potential obtained from the Super Dual Auroral Radar Network (SuperDARN) and, then, estimate the degree of disorder and the degree of complexity of ionospheric convection under different Interplanetary Magnetic Field (IMF) conditions. The aforementioned quantities are computed starting from time series of the coefficients of the 4th order spherical harmonics expansion of the polar cap potential for three periods, characterised by: (i) steady IMF Bz > 0, (ii) steady IMF Bz < 0 and (iii) a double rotation from negative to positive and then positive to negative Bz. A neat dynamical topological transition is observed when the IMF Bz turns from negative to positive and vice versa, pointing toward the possible occurrence of an order/disorder phase transition, which is the counterpart of the large scale convection rearrangement and of the increase of the global coherence. This result has been confirmed by applying the same analysis to a larger data base of about twenty days of SuperDARN data, allowing to investigate the role of IMF By too

Preserved Extra-Foveal Processing of Object Semantics in Alzheimer’s Disease

Alzheimer’s disease (AD) patients underperform on a range of tasks requiring semantic processing, but it is unclear whether this impairment is due to a generalised loss of semantic knowledge or to issues in accessing and selecting such information from memory. The objective of this eye-tracking visual search study was to determine whether semantic expectancy mechanisms known to support object recognition in healthy adults are preserved in AD patients. Furthermore, as AD patients are often reported to be impaired in accessing information in extra-foveal vision, we investigated whether that was also the case in our study. Twenty AD patients and 20 age-matched controls searched for a target object among an array of distractors presented extra-foveally. The distractors were either semantically related or unrelated to the target (e.g., a car in an array with other vehicles or kitchen items). Results showed that semantically related objects were detected with more difficulty than semantically unrelated objects by both groups, but more markedly by the AD group. Participants looked earlier and for longer at the critical objects when these were semantically unrelated to the distractors. Our findings show that AD patients can process the semantics of objects and access it in extra-foveal vision. This suggests that their impairments in semantic processing may reflect difficulties in accessing semantic information rather than a generalised loss of semantic memory

A preliminary study of the subsoil of the Roman Amphitheatre of Catania (Sicily) through integrated geophysical and stratigraphic data

To reconstruct the stratigraphy of the subsoil and the geometry of the lava deposits beneath the Roman Amphitheatre located within the city of Catania (Sicily) we performed non-invasive geophysical prospections (seismic and electric tomography). In urbanized contexts this kind of surveys represents the best support to following more specific studies aimed at the conservation of monuments. Seismic tomography allowed us to reconstruct seismostratigraphic sections by imaging the distribution of seismic waves velocity in the internal ambulatory wall and its substrate and outside the Amphitheatre. Electric tomography allowed us to image the resistivity distribution outside the Amphitheatre and to locate anomalies related to the possible presence of cavities, water table and waste waters. The stratigraphic data obtained from mechanical drillings carried out in the study area were used to calibrate the information obtained from the geophysical surveys

Novel antiproliferative biphenyl nicotinamide: NMR metabolomic study of its effect on the MCF-7 cell in comparison with cisplatin and vinblastine

A 1H-NMR-based metabolomic study was performed on MCF-7 cell lines treated with a novel nicotinamide derivative (DT-8) in comparison with two drugs characterized by a well-established mechanism of action, namely the DNA-metalating drug cisplatin (cis-diamminedichloridoplatinum(II), CDDP) and the antimitotic drug vinblastine (vinblastine, VIN). The effects of the three compounds, each one at the concentration corresponding to the IC50 value, were investigated, with respect to the controls (K), by the 1H-NMR of cells lysates and multivariate analysis (MVA) of the spectroscopic data. Relevant differences were found in the metabolic profiles of the different treatments with respect to the controls. A large overlap of the metabolic profiles in DT-8 vs. K and VIN vs. K suggests a similar biological response and mechanism of action, significantly diverse with respect to CDDP. On the other hand, DT8 seems to act by disorganizing the mitotic spindle and ultimately blocking the cell division, through a mechanism implying methionine depletion and/or S-adenosylmethionine (SAM) limitation

Different responses of northern and southern high latitude ionospheric convection to IMF rotations: a case study based on SuperDARN observations

Abstract. We use SuperDARN data to study high-latitude ionospheric convection over a three hour period (starting at 22:00 UT on 2 January 2003), during which the Interplanetary Magnetic Field (IMF) flipped between two states, one with By&amp;gt;&amp;gt;|Bz| and one with Bz&amp;gt;0, both with negative Bx. We find, as expected from previous works, that day side ionospheric convection is controlled by the IMF in both hemispheres. For strongly northward IMF, we observed signatures of two reverse cells, both in the Northern Hemisphere (NH) and in the Southern Hemisphere (SH), due to lobe reconnection. On one occasion, we also observed in the NH two viscous cells at the sides of the reverse cell pair. For duskward IMF, we observed in the NH a large dusk clockwise cell, accompanied by a smaller dawn cell, and the signature of a corresponding pattern in the SH. On two occasions, a three cell pattern, composed of a large clockwise cell and two viscous cells, was observed in the NH. As regards the timings of the NH and SH convection reconfigurations, we find that the convection reconfiguration from a positive Bz dominated to a positive By dominated pattern occurred almost simultaneously (i.e. within a few minutes) in the two hemispheres. On the contrary, the reconfiguration from a By dominated to a northward IMF pattern started in the NH 8–13 min earlier than in the SH. We suggest that part of such a delay can be due to the following mechanism: as IMF Bx&amp;lt;0, the northward-tailward magnetosheath magnetic field reconnects with the magnetospheric field first tailward of the northern cusp and later on tailward of the southern cusp, due to the IMF draping around the magnetopause.</p