Geographical perspectives on epidemic transmission of cholera in Haiti, October 2010 through March 2013

The current epidemic of El Tor cholera in the Caribbean republic of Haiti is one of the largest single outbreaks of the disease ever recorded. The prospects are that the epidemic will continue to present challenges to workers in public health medicine, epidemiology and allied fields in the social sciences for years to come. This article introduces geographers to the environmental context of the Haiti cholera epidemic, the principal data sources available to analyze the occurrence of the epidemic, and evidence regarding its geographical origins and dispersal during the first thirty months of the epidemic, October 2010–March 2013. Using weekly case data collated by the Haitian Ministère de la Santé Publique et de la Population (MSPP), techniques of time series analysis are used to examine inter- and intra-departmental patterns of cholera activity. Our analysis demonstrates a pronounced lag structure to the spatial development of the epidemic (Artibonite and northern departments Ouest and metropolitan Port-au-Prince southern departments). Observed variations in levels of epidemiological integration, both within and between departments, provide new perspectives on the spatio-temporal evolution of the epidemic to its March 2013 pattern

Theresienstadt: A Geographical Picture of Transports, Demography, and Communicable Disease in a Jewish Camp-Ghetto, 1941–45

The Nazi ghetto system was one of the principal vehicles for the persecution of Jewish and other peoples in German-occupied Europe in World War II. Transport and confinement – twin pillars of the ghetto system – were intrinsically geographical matters that operated on scales from the international to the local and which shaped the demographic and epidemiological character of ghettos across Eastern Europe. This article uses geographical techniques of map-based visualisation and spatial analysis to portray the demographic and epidemic history of the Nazi ‘model’ camp-ghetto at Theresienstadt (Terezín) in the former German Protectorate of Bohemia and Moravia, 1941–45. Our study reconstructs the space-time pattern and demographic structure of transports of Jewish prisoners to the ghetto and their association with substantial outbreaks of communicable diseases in the ghetto. The study highlights the importance of a geographical approach to an understanding of the demographic and public health impacts of both the Holocaust and other genocidal events

A method for developing the true stress-strain relationship for structural steels based on tension coupon tests

Predicting the uniaxial stress-stress response of ductile metals like structural steel can provide valuable insight into a broad range of engineering problems. Despite a wide body of research covering more than a century, the approach and guidance related to developing the true stress-strain relationship for ductile metals—specifically structural steels—continues to change and evolve. In particular, guidance related to accurate prediction of the onset of necking and post-necking response remains a topic of ongoing research and capturing these effects remains a challenge to researchers and engineers. The research presented in this dissertation was undertaken to extend the body of knowledge in this area. Particular emphasis is placed on developing a true stress-strain relationship for structural steels that is capable of capturing the onset of necking and post-necking behavior up to fracture. In addition, as standard tension coupon load-deformation data are often the only available information from which to develop such a model, the processes and guidance presented in this dissertation require only that input information. Therefore, advanced experimental approaches and measurement techniques are not required to leverage the guidance presented herein. This path was chosen in the hopes of providing guidance that would be broadly applicable to a wide range of problems, industries, research, and practicing professionals. This dissertation proposes a method for developing a true stress-strain relationship for structural steels that can be directly used in predictive finite element analysis (FEA) models using three-dimensional (3D) solid elements. The result of this research indicate that such a model should be able to reproduce the experimental results of the tension test quite accurately, providing validation and verification of the assumed material definition. Additionally, three derivative rules are presented. These rules were distilled from existing research and provide simple guidelines for capturing necking, maintaining computational stability and uniqueness, and prohibiting post-necking cold-drawing behavior. The rules are incorporated into the recommended process for developing the true stress-strain relationship for structural steels; however, they are also presented separately so they can easily be incorporated into alternate methods for defining such a constitutive relationship. Finally, while this research has furthered the understanding of the true stress-strain relationship of structural steels, particularly in predicting necking and post-necking behavior, there is still considerable room for additional research on this topic. For example, automation, incorporating error minimizing techniques, and adding local and material-level and microstructural phenomena (e.g., void formation, growth and coalescence) each offer great potential for extending and improving the recommendations presented in this dissertation. Thus, while this effort has intentionally maintained a limited focus, it is the authors hope that it serves others as one more small step toward accurate prediction of the load-deformation behavior of structural steels and other ductile metals.Civil, Architectural, and Environmental Engineerin

Suzbijanje geografskog širenja zaraze: kuga u Italiji od 1347.-1851.

After the establishment of the first quarantine station in the Republic of Ragusa (modern-day Dubrovnik) in 1377, the states and principalities of Italy developed a sophisticated system of defensive quarantine in an attempt to protect themselves from the ravages of plague. Using largely unknown and unseen historical maps, this paper reconstructs the extent and operation of the system used. It is shown that a cordon sanitaire existed around the coast of Italy for several centuries, consisting of three elements: (i) an outer defensive ring of armed sailing boats in the Mediterranean and the Adriatic, (ii) a middle coastal ring of forts and observation towers, and (iii) an inner defensive ring of land-based cavalry. The principles established, although not especially successful at the time against a disease of (then) unknown aetiology, are still used today in attempts to control the spread of infections of animal and human populations.Nakon uspostave prvoga lazareta u Dubrovačkoj Republici 1377., talijanske državice i kneževine razradile su sustav karantena kako bi se zaštitile od razarajućega djelovanja kuge. Oslanjajući se mahom na dosad nepoznate povijesne karte, u ovome se članku rekonstruira kako je i u kojem razmjeru djelovao sustav zaštite. Duž talijanske obale stoljećima je postojao sanitarni kordon, a sastojao se od tri dijela: (i) vanjski pojas sastavljen od naoružanih jedrenjaka na Sredozemnom i Jadranskome moru, (ii) srednji obrambeni pojas sastavljen od utvrda i promatračnica te (iii) unutarnji obrambeni pojas na kopnu sastavljen od konjice. Premda ovaj sustav svojevremeno i nije bio pretjerano uspješan u zaštiti od bolesti (tada) nepoznate etiologije, njegova se načela još uvijek rabe za sprječavanje širenja bolesti među ljudima i životinjama

Operation Pied Piper: a geographical reappraisal of the impact of wartime evacuation on scarlet fever and diphtheria rates in England and Wales, 1939–1945

This paper examines the geographical impact of the British Government’s wartime evacuation scheme on notified rates of two common acute childhood diseases (scarlet fever and diphtheria) in the 1470 local government districts of England and Wales, 1939–1945. Drawing on the notifications of communicable diseases collated by the General Register Office (GRO), we establish pre-war (baseline) disease rates for the 1470 districts. For the war years, techniques of binary logistic regression analysis are used to assess the associations between (a) above-baseline (‘raised’) disease rates in evacuation, neutral and reception districts and (b) the major phases of the evacuation scheme. The analysis demonstrates that the evacuation was temporally associated with distinct national and regional effects on notified levels of disease activity. These effects were most pronounced in the early years of the dispersal (1939–1941) and corresponded with initial levels of evacuation-related population change at the regional and district scales

Relationship between Processing Method and the Glycemic Indices of Ten Sweet Potato (Ipomoea batatas) Cultivars Commonly Consumed in Jamaica

This study investigated the effect of different traditional cooking methods on glycemic index (GI) and glycemic response of ten Sweet potato (Ipomoea batatas) cultivars commonly eaten in Jamaica. Matured tubers were cooked by roasting, baking, frying, or boiling then immediately consumed by the ten nondiabetic test subjects (5 males and 5 females; mean age of 27 ± 2 years). The GI varied between 41 ± 5–93 ± 5 for the tubers studied. Samples prepared by boiling had the lowest GI (41 ± 5–50 ± 3), while those processed by baking (82 ± 3–94 ± 3) and roasting (79 ± 4–93 ± 2) had the highest GI values. The study indicates that the glycemic index of Jamaican sweet potatoes varies significantly with the method of preparation and to a lesser extent on intravarietal differences. Consumption of boiled sweet potatoes could minimize postprandial blood glucose spikes and therefore, may prove to be more efficacious in the management of type 2 diabetes mellitus