100 research outputs found
Negotiations, Sanctions, and Iranian Politics
On an issue as complex as that of the Iranian nuclear program, analysts have an obligation to firmly uphold the importance of first principles, not just the latest twists and turns which so dominate the news and can distract policymakers. Three such principles are: by what yardsticks can diplomacy\u27s progress be judged? what would constitute success for sanctions? and what are the key concerns of the Iranian side in the negotiations
The Prospects for Regime Change in Iran and the Controversy about U.S. Policy
The protest movement following the 12 June 2009 Iranian presidential election raised the question of what should be the European and American policy towards democratic forces in Iran. Another way of framing the issue is: should the West support regime change in Iran as an objective? Serious arguments can be made that the West should instead concentrate on resolving the nuclear standoff, even if Iran has an odious government. But there are two serious complications to any effort to reassure Tehran that the West is prepared to accept the regime so long as it agrees to a nuclear deal: Iranian leaders would not believe such a U.S. statement no matter what actions the U.S. government takes, and the United States has a strong interest in the cause of democracy in Iran
Experimental and Computational Studies of Cortical Neural Network Properties Through Signal Processing
Previous studies, both theoretical and experimental, of network level dynamics in the cerebral cortex show evidence for a statistical phenomenon called criticality; a phenomenon originally studied in the context of phase transitions in physical systems and that is associated with favorable information processing in the context of the brain. The focus of this thesis is to expand upon past results with new experimentation and modeling to show a relationship between criticality and the ability to detect and discriminate sensory input. A line of theoretical work predicts maximal sensory discrimination as a functional benefit of criticality, which can then be characterized using mutual information between sensory input, visual stimulus, and neural response,. The primary finding of our experiments in the visual cortex in turtles and neuronal network modeling confirms this theoretical prediction. We show that sensory discrimination is maximized when visual cortex operates near criticality. In addition to presenting this primary finding in detail, this thesis will also address our preliminary results on change-point-detection in experimentally measured cortical dynamics
Getting Ready for a Nuclear-Ready Iran
As Iran edges closer to acquiring a nuclear bomb and its missiles extend an ever darker diplomatic shadow over the Middle East and Europe, Iran is likely to pose three threats. First, Iran could dramatically up the price of oil by interfering with the free passage of vessels in and through the Persian Gulf as it did during the l980s or by threatening to use terrorist proxies to target other states\u27 oil facilities. Second, it could diminish American influence in the Gulf and Middle East by increasing the pace and scope of terrorist activities against Iraq, Saudi Arabia, other Gulf states, Israel, and other perceived supporters of the United States. Finally, it could become a nuclear proliferation model for the world and its neighbors (including many states that otherwise would be more dependent on the United States for their security) by continuing to insist that it has a right to make nuclear fuel under the Nuclear Nonproliferation Treaty and then withdrawing once it decides to get a bomb. To contain and deter Iran from posing such threats, the United States and its friends could take a number of steps: increasing military cooperation (particularly in the naval sphere) to deter Iranian naval interference; reducing the vulnerability of oil facilities in the Gulf outside of Iran to terrorist attacks, building and completing pipelines in the lower Gulf region that would allow most of the non-Iranian oil and gas in the Gulf to be exported without having to transit the Straits of Hormuz; diplomatically isolating Iran by calling for the demilitarization of the Straits and adjacent islands, creating country-neutral rules against Nuclear Nonproliferation Treaty state members who are suspected of violating the treaty from getting nuclear assistance from other state members and making withdrawal from the treaty more difficult; encouraging Israel to set the pace of nuclear restraint in the region by freezing its large reactor at Dimona and calling on all other states that have large nuclear reactors to follow suit; and getting the Europeans to back targeted economic sanctions against Iran if it fails to shut down its most sensitive nuclear activities.https://press.armywarcollege.edu/monographs/1726/thumbnail.jp
Liberal market economies, business, and political finance: Britain under New Labour
The extent and nature of business financing of parties is an important feature of political finance. Britainâs transparent and permissive regulatory system provides an excellent opportunity to study business financing of parties. Business donations have been very important to the Conservative party over the last decade, and of only marginal importance to Labour. Unlike other Conservative contributors, business donors are more likely to contribute when the party is popular. In contrast to the previous period of Conservative government, the biggest British businesses tended to abstain from political finance under New Labour. However, their bias towards the Conservatives is affected by the partyâs popularity and the closeness of an election. Britain shares the political importance of business financing of parties and its mixture of ideological and pragmatic motivations with other liberal market economies. However, in Britain the bias towards the right is much stronger and the role of big business more marginal
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A high-resolution map of human evolutionary constraint using 29 mammals.
The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the human genome has undergone purifying selection, and locate constrained elements covering âŒ4.2% of the genome. We use evolutionary signatures and comparisons with experimental data sets to suggest candidate functions for âŒ60% of constrained bases. These elements reveal a small number of new coding exons, candidate stop codon readthrough events and over 10,000 regions of overlapping synonymous constraint within protein-coding exons. We find 220 candidate RNA structural families, and nearly a million elements overlapping potential promoter, enhancer and insulator regions. We report specific amino acid residues that have undergone positive selection, 280,000 non-coding elements exapted from mobile elements and more than 1,000 primate- and human-accelerated elements. Overlap with disease-associated variants indicates that our findings will be relevant for studies of human biology, health and disease
Ideological Labels in America
This paper extends Ellis and Stimsonâs (Ideology in America. New York: Cambridge UniversityPress, 2012) study of the operational-symbolic paradox using issue-level measures of ideological incongruence based on respondent positions and symbolic labels for these positions across 14 issues. Like Ellis and Stimson, we find that substantial numbersâover 30Â %âof Americans experience conflicted conservatism. Our issue-level data reveal, furthermore, that conflicted conservatism is most common on the issues of education and welfare spending. In addition, we also find that 20Â % of Americans exhibit conflicted liberalism. We then replicate Ellis and Stimsonâs finding that conflicted conservatism is associated with low sophistication and religiosity, but also find that it is associated with being socialized in a post-1960s generation and using Fox News as a main news source. Finally, we show the important role played by identities, with both conflicted conservatism and conflicted liberalism linked with partisan and ideological identities, and conflicted liberalism additionally associated with ethnic identities
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