Molecular Gas in the NGC 6240 Merging Galaxy System at the Highest Spatial Resolution

We present the highest-resolution—15 pc (0.”03)—ALMA ¹²CO(2–1) line emission and 1.3 mm continuum maps, tracers of the molecular gas and dust, respectively, in the nearby merging galaxy system NGC 6240, which hosts two supermassive black holes growing simultaneously. These observations provide an excellent spatial match to existing Hubble Space Telescope (HST) optical and near-infrared observations of this system. A significant molecular gas mass, ~9 × 10⁹ M⊙, is located between the two nuclei, forming a clumpy stream kinematically dominated by turbulence, rather than a smooth rotating disk, as previously assumed from lower-resolution data. Evidence for rotation is seen in the gas surrounding the southern nucleus but not in the northern one. Dynamical shells can be seen, likely associated with nuclear supernova remnants. We further detect the presence of significant high-velocity outflows, some of them reaching velocities >500 km s⁻¹, affecting a significant fraction, ~11%, of the molecular gas in the nuclear region. Inside the spheres of influence of the northern and southern supermassive black holes, we find molecular masses of 7.4 × 10⁸ and 3.3 × 10⁹ M⊙, respectively. We are thus directly imaging the reservoir of gas that can accrete onto each supermassive black hole. These new ALMA maps highlight the critical need for high-resolution observations of molecular gas in order to understand the feeding of supermassive black holes and its connection to galaxy evolution in the context of a major galaxy merger

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation

Desmosomes are cell–cell adhesion sites and part of the intercalated discs, which couple adjacent cardiomyocytes. The connection is formed by the extracellular domains of desmosomal cadherins that are also linked to the cytoskeleton on the cytoplasmic side. To examine the contribution of the desmosomal cadherin desmoglein 2 to cardiomyocyte adhesion and cardiac function, mutant mice were prepared lacking a part of the extracellular adhesive domain of desmoglein 2. Most live born mutant mice presented normal overall cardiac morphology at 2 weeks. Some animals, however, displayed extensive fibrotic lesions. Later on, mutants developed ventricular dilation leading to cardiac insufficiency and eventually premature death. Upon histological examination, cardiomyocyte death by calcifying necrosis and replacement by fibrous tissue were observed. Fibrotic lesions were highly proliferative in 2-week-old mutants, whereas the fibrotic lesions of older mutants showed little proliferation indicating the completion of local muscle replacement by scar tissue. Disease progression correlated with increased mRNA expression of c-myc, ANF, BNF, CTGF and GDF15, which are markers for cardiac stress, remodeling and heart failure. Taken together, the desmoglein 2-mutant mice display features of dilative cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy, an inherited human heart disease with pronounced fibrosis and ventricular arrhythmias that has been linked to mutations in desmosomal proteins including desmoglein 2

Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network

Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

The Molecular Gas in the NGC 6240 Merging Galaxy System at the Highest Spatial Resolution

We present the highest-resolution - 15 pc (0.″03) - ALMA 12CO(2-1) line emission and 1.3 mm continuum maps, tracers of the molecular gas and dust, respectively, in the nearby merging galaxy system NGC 6240, which hosts two supermassive black holes growing simultaneously. These observations provide an excellent spatial match to existing Hubble Space Telescope (HST) optical and near-infrared observations of this system. A significant molecular gas mass, ∼9 × 109 M o˙, is located between the two nuclei, forming a clumpy stream kinematically dominated by turbulence, rather than a smooth rotating disk, as previously assumed from lower-resolution data. Evidence for rotation is seen in the gas surrounding the southern nucleus but not in the northern one. Dynamical shells can be seen, likely associated with nuclear supernova remnants. We further detect the presence of significant high-velocity outflows, some of them reaching velocities \u3e500 km s-1, affecting a significant fraction, ∼11%, of the molecular gas in the nuclear region. Inside the spheres of influence of the northern and southern supermassive black holes, we find molecular masses of 7.4 × 108 and 3.3 × 109 M o˙, respectively. We are thus directly imaging the reservoir of gas that can accrete onto each supermassive black hole. These new ALMA maps highlight the critical need for high-resolution observations of molecular gas in order to understand the feeding of supermassive black holes and its connection to galaxy evolution in the context of a major galaxy merger

A cross-disciplinary roundtable on the feminist politics of translation

This introduction explores the feminist politics of translation from different disciplinary, epistemological and geopolitical perspectives and locations. It also explores that ways in which translation could be used as a means for feminist activism. One feminism activist feels that a key part of feminisms must focus on how to address the forms of violence that emanate from context-specific entanglements and relations of power, difference and knowledge. Another activist sees translation as essential to feminist activism—in other words, there can be no successful feminist politics without translation. Two co-editors of Trans-localities/Translocalidades: Feminist Politics of Translation in the Latin/a Americas feel that since the Latin/Américas is a transborder cultural formation rather than a territorially delimited one, translation is politically and theoretically indispensable to forging feminist, pro-social-justice, anti-racist, postcolonial/decolonial and anti-imperial political alliances and epistemologies. To understand the coloniality of power, one needs to grasp the unequal travels and translations of feminist theories, texts and practices, as well as their reception