Magnification and evolution bias of transient sources: GWs and SNIa

Third-generation gravitational wave (GW) observatories such as the Einstein Telescope and Cosmic Explorer, together with the LSST survey at the Vera Rubin Observatory, will yield an abundance of extra-galactic transient objects. This opens the exciting possibility of using GW sources and Supernovae Type Ia (SNIa) as luminosity distance tracers of large-scale structure for the first time. The large volumes accessible to these surveys imply that we may need to include relativistic corrections, such as lensing and Doppler magnification. However, the amplitude of these effects depends on the magnification and evolution biases of the transient sources, which are not yet understood. In this paper we develop comprehensive frameworks to address and model these biases for both populations of transient objects; in particular, we define how to compute these biases for GW sources. We then analyse the impact of magnification and evolution biases on the relativistic corrections and on the angular power spectrum of these sources. We show that correct modelling and implementation of these biases is crucial for measuring the cross-correlations of transient sources at higher redshifts.Comment: 28 pages, 14 figures, 4 tables, comments welcom

Mine for life:charting ownership effects in memory from adolescence to old age

The current study investigates the Self Reference Effect (SRE) with an ownership memory task across several age groups, providing the first age exploration of implicit ownership memory biases from adolescence to older adulthood (N = 159). Using a well-established ownership task (Cunningham et al., 2008; Sparks et al., 2016; Clarkson et al., 2022), participants were required to sort images of grocery items as belonging to themselves or to a fictious unnamed Other. After sorting and a brief distractor task, participants completed a surprise one-step source memory test. Overall, there was a robust SRE, with greater source memory accuracy for self-owned items. The SRE attenuated with age, such that the magnitude of difference between self and other memory diminished into older adulthood. Importantly, these findings were not due to a deterioration of memory for self-owned items, but rather an increase in memory performance for other-owned items. Linear mixed effects analyses showed self-biases in reaction times, such that self-owned items were identified more rapidly compared with other owned items. Again, age interacted with this effect showing that the responses of older adults were slowed, especially for other-owned items. Several theoretical implications were drawn from these findings, but we suggest that older adults may not experience ownership-related biases to the same degree as younger adults. Consequently, SREs through the lens of mere ownership may attenuate with age

Evaluation of Interpretability for Deep Learning algorithms in EEG Emotion Recognition: A case study in Autism

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has been an increase in the application of Deep Learning in clinical trials to predict early diagnosis of neuro-developmental disorders, such as Autism Spectrum Disorder (ASD). However, the inclusion of more reliable saliency-maps to obtain more trustworthy and interpretable metrics using neural activity features is still insufficiently mature for practical applications in diagnostics or clinical trials. Moreover, in ASD research the inclusion of deep classifiers that use neural measures to predict viewed facial emotions is relatively unexplored. Therefore, in this study we propose the evaluation of a Convolutional Neural Network (CNN) for electroencephalography (EEG)-based facial emotion recognition decoding complemented with a novel RemOve-And-Retrain (ROAR) methodology to recover highly relevant features used in the classifier. Specifically, we compare well-known relevance maps such as Layer-Wise Relevance Propagation (LRP), PatternNet, Pattern-Attribution, and Smooth-Grad Squared. This study is the first to consolidate a more transparent feature-relevance calculation for a successful EEG-based facial emotion recognition using a within-subject-trained CNN in typically-developed and ASD individuals

A multivariate analysis of women's mating strategies and sexual selection on men's facial morphology

The strength and direction of sexual selection via female choice on masculine facial traits in men is a paradox in human mate choice research. While masculinity may communicate benefits to women and offspring directly (i.e. resources) or indirectly (i.e. health), masculine men may be costly as long-term partners owing to lower paternal investment. Mating strategy theory suggests women's preferences for masculine traits are strongest when the costs associated with masculinity are reduced. This study takes a multivariate approach to testing whether women's mate preferences are context-dependent. Women (n = 919) rated attractiveness when considering long-term and short-term relationships for male faces varying in beardedness (clean-shaven and full beards) and facial masculinity (30% and 60% feminized, unmanipulated, 30% and 60% masculinized). Participants then completed scales measuring pathogen, sexual and moral disgust, disgust towards ectoparasites, reproductive ambition, self-perceived mate value and the facial hair in partners and fathers. In contrast to past research, we found no associations between pathogen disgust, self-perceived mate value or reproductive ambition and facial masculinity preferences. However, we found a significant positive association between moral disgust and preferences for masculine faces and bearded faces. Preferences for beards were lower among women with higher ectoparasite disgust, providing evidence for ectoparasite avoidance hypothesis. However, women reporting higher pathogen disgust gave higher attractiveness ratings for bearded faces than women reporting lower pathogen disgust, providing support for parasite-stress theories of sexual selection and mate choice. Preferences for beards were also highest among single and married women with the strongest reproductive ambition. Overall, our results reflect mixed associations between individual differences in mating strategies and women's mate preferences for masculine facial traits

Multivariate Intra-Sexual Selection on Men’s Perceptions of Male Facial Morphology

Objectives Intra-sexual selection has shaped the evolution of sexually dimorphic traits in males of many primates, including humans. In men, sexual dimorphism in craniofacial shape (i.e. facial masculinity) and facial hair have both been shown to communicate aspects of social and physical dominance intra-sexually. However, less attention has been given to how variation in physical and social dominance among receivers impacts on perceptions of facial masculinity and beards as intra-sexual signals of formidability. Methods In the current study, male participants (N = 951) rated male faces varying in masculinity and beardedness when judging masculinity, dominance and aggressiveness. These participants also responded to scales measuring their psychological dominance, sexual jealousy, status seeking, and masculine morphology (facial masculinity, facial hair, and height). Results Beardedness exerted strong effects over clean-shaven faces on ratings of masculinity, dominance, and aggressiveness. Trait ratings of masculinity, dominance, and aggressiveness rose linearly with increasing craniofacial masculinity. The significant facial masculinity × facial hair interaction suggests that beardedness caused strong effects on all trait ratings over clean-shaven faces at every level of facial masculinity. Participants with full beards also reported higher scores on dominance and assertiveness scales. Participants high in dominance and assertiveness also gave higher ratings for dominance, but not masculinity or aggressiveness, to bearded over clean-shaven faces. Participants low in intra-sexual jealousy rated clean-shaven and/or feminised faces as less dominant, less masculine, and less aggressive. Conclusions These findings demonstrate that facial hair enhances perceptions of masculinity, dominance, and aggressiveness above ratings of facial masculinity, potentially by augmenting masculine craniofacial features. Individual differences in intra-sexual dominance showed associations with judgments of facial hair but not facial masculinity. Our study demonstrates that when two sexually dimorphic androgen dependent facial traits are judged in concert, ornamental rather than structural masculine facial features underpin men’s intra-sexual judgments of formidability

Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib

Imatinib mesylate induces complete cytogenetic responses in patients with chronic myeloid leukemia (CML), yet many patients have detectable BCR-ABL transcripts in peripheral blood even after prolonged therapy. Bone marrow studies have shown that this residual disease resides within the stem cell compartment. Quiescence of leukemic stem cells has been suggested as a mechanism conferring insensitivity to imatinib, and exposure to the Granulocyte-Colony Stimulating Factor (G-CSF), together with imatinib, has led to a significant reduction in leukemic stem cells in vitro. In this paper, we design a novel mathematical model of stem cell quiescence to investigate the treatment response to imatinib and G-CSF. We find that the addition of G-CSF to an imatinib treatment protocol leads to observable effects only if the majority of leukemic stem cells are quiescent; otherwise it does not modulate the leukemic cell burden. The latter scenario is in agreement with clinical findings in a pilot study administering imatinib continuously or intermittently, with or without G-CSF (GIMI trial). Furthermore, our model predicts that the addition of G-CSF leads to a higher risk of resistance since it increases the production of cycling leukemic stem cells. Although the pilot study did not include enough patients to draw any conclusion with statistical significance, there were more cases of progression in the experimental arms as compared to continuous imatinib. Our results suggest that the additional use of G-CSF may be detrimental to patients in the clinic

Playing the Public Lands Game- HONR 3020: Engaging Utah\u27s Public Lands

How to get involved with public land issues and learn what\u27s at stake. Join us as students present a guide that teaches how to locate, navigate, and participate in the various government and public processes for engaging in public lands debates

Sources of stakeholder salience in the responsible investment movement: why do investors sign the Principles for Responsible Investment?

Since its inception in 2006, the United Nations-backed Principles for Responsible Investment (PRI) have grown to over 1300 signatories representing over $45 trillion. This growth is not slowing down. In this paper, we argue that there is a set of attributes which make the PRI salient as a stakeholder and its claim to sign the six PRI important to institutional investors. We use Mitchell et al.’s (Acad Manag Rev 22:853–886, 1997) theoretical framework of stakeholder salience, as extended by Gifford (J Bus Eth 92:79–97, 2010). We use as evidence confidential data from the annual survey of signatories carried out by the PRI in a 5-year period between 2007 and 2011. The findings highlight pragmatic and organizational legitimacy, normative and utilitarian power, and management values as the attributes that contribute most to the salience of the PRI as a stakeholder

Shifting saliency of the 'Other' modulates the Self Reference Effect

The OSF project page contains the data underlying the published research output: Clarkson, T. R., Cunningham, S. J., Haslam, C., & Kritikos, A. (2022). Is self always prioritised? Attenuating the ownership self-reference effect in memory. Consciousness and Cognition, 106, [103420]. https://doi.org/10.1016/j.concog.2022.10342