Improving Access to Psychological Therapy: Initial Evaluation of the Two Demonstration Sites

The Government's Improving Access to Psychological Therapy (IAPT) programme aims to implement NICE Guidance for people with depression and anxiety disorders. In the first phase of the programme, two demonstration sites were established in Doncaster and Newham with funding to provide increased availability of cognitive-behaviour therapy-based (CBT) services to those in the community who need them. The services opened in late summer 2006. This paper documents the achievements of the sites up to September 2007 (roughly their first year of operation) and makes recommendations for the future roll out of IAPT services.Cognitive Behavioural Therapy, CBT, Psychological therapy, Evaluation, Cost benefit analysis, IAPT

Fitzgerald in the Late 1910s: War and Women

This dissertation analyzes historical and cultural factors that influenced F. Scott Fitzgerald\u27s portrayal of women in three of his early works. In Sentiment—and the Use of Rouge, This Side of Paradise, and Head and Shoulders, women act as usurpers and destroyers, infiltrating male territory and taking on traditionally male roles. Fitzgerald reacts to changes in the status of women that had been occurring since the late 1800s. But the late 1910s, when the author composed these works, witnessed a hastening of women\u27s progress and an intensification of the male anxiety resulting from these changes. Repercussions of the war in Europe did much to exacerbate men\u27s fears. Here, I examine the many ways in which the war influenced American culture and how Fitzgerald, something of a self-appointed voice of his generation reflected the male panic resulting from changes in gender relations. To do so, I attempt to recover and reconstruct the zeitgeist of the late 1910s through an extensive reading of period print media. Chapter 1 treats Sentiment, one of the few Fitzgerald works to deal directly with the war. American periodicals published many articles dealing with European—and especially British—reactions to the war. Sentiment dramatizes controversies surrounding changes in fashion, war babies, khaki fever, and eugenics. In chapter 2, I discuss Fitzgerald\u27s portrayal of the automobile in Paradise. Fitzgerald documents the new freedoms that young men and women of the 1910s enjoyed and the role the devil wagon —as period sources called the automobile—played in this liberation. The print media of the 1910s celebrated the motor vehicle\u27s role on the battlefield and the woman driver\u27s contributions to the war effort, thus creating an association between women, cars, and battlefield death. In the novel, the car becomes a vehicle of moral and physical destruction. Finally, I read Head as a commentary on gender role reversals during the war, when women invaded traditionally male territory in the workplace. This usurpation of male roles went all the way to the White House: Edith Wilson secretly made important political decisions as her husband Woodrow lay incapacitated after a stroke

Decoherence of a quantum memory coupled to a collective spin bath

We study the quantum dynamics of a single qubit coupled to a bath of interacting spins as a model for decoherence in solid state quantum memories. The spin bath is described by the Lipkin-Meshkov-Glick model and the bath spins are subjected to a transverse magnetic field. We investigate the qubit interacting via either an Ising- or an XY-type coupling term to subsets of bath spins of differing size. The large degree of symmetry of the bath allows us to find parameter regimes where the initial qubit state is revived at well defined times after the qubit preparation. These times may become independent of the bath size for large baths and thus enable faithful qubit storage even in the presence of strong coupling to a bath. We analyze a large range of parameters and identify those which are best suited for quantum memories. In general we find that a small number of links between qubit and bath spins leads to less decoherence and that systems with Ising coupling between qubit and bath spins are preferable.Comment: 13 pages, 8 figure

Transcriptome profiling of a spirodiclofen susceptible and resistant strain of the European red mite Panonychus ulmi using strand-specific RNA-seq

Background: The European red mite, Panonychus ulmi, is among the most important mite pests in fruit orchards, where it is controlled primarily by acaricide application. However, the species rapidly develops pesticide resistance, and the elucidation of resistance mechanisms for P. ulmi has not kept pace with insects or with the closely related spider mite Tetranychus urticae. The main reason for this lack of knowledge has been the absence of genomic resources needed to investigate the molecular biology of resistance mechanisms. Results: Here, we provide a comprehensive strand-specific RNA-seq based transcriptome resource for P. ulmi derived from strains susceptible and resistant to the widely used acaricide spirodiclofen. From a de novo assembly of the P. ulmi transcriptome, we manually annotated detoxification enzyme families, target-sites of commonly used acaricides, and horizontally transferred genes implicated in plant-mite interactions and pesticide resistance. In a comparative analysis that incorporated sequences available for Panonychus citri, T. urticae, and insects, we identified radiations for detoxification gene families following the divergence of Panonychus and Tetranychus genera. Finally, we used the replicated RNA-seq data from the spirodiclofen susceptible and resistant strains to describe gene expression changes associated with resistance. A cytochrome P450 monooxygenase, as well as multiple carboxylcholinesterases, were differentially expressed between the susceptible and resistant strains, and provide a molecular entry point for understanding resistance to spirodiclofen, widely used to control P. ulmi populations. Conclusions: The new genomic resources and data that we present in this study for P. ulmi will substantially facilitate molecular studies of underlying mechanisms involved in acaricide resistance

The Compositional Structure of the Asteroid Belt

The past decade has brought major improvements in large-scale asteroid discovery and characterization with over half a million known asteroids and over 100,000 with some measurement of physical characterization. This explosion of data has allowed us to create a new global picture of the Main Asteroid Belt. Put in context with meteorite measurements and dynamical models, a new and more complete picture of Solar System evolution has emerged. The question has changed from "What was the original compositional gradient of the Asteroid Belt?" to "What was the original compositional gradient of small bodies across the entire Solar System?" No longer is the leading theory that two belts of planetesimals are primordial, but instead those belts were formed and sculpted through evolutionary processes after Solar System formation. This article reviews the advancements on the fronts of asteroid compositional characterization, meteorite measurements, and dynamical theories in the context of the heliocentric distribution of asteroid compositions seen in the Main Belt today. This chapter also reviews the major outstanding questions relating to asteroid compositions and distributions and summarizes the progress and current state of understanding of these questions to form the big picture of the formation and evolution of asteroids in the Main Belt. Finally, we briefly review the relevance of asteroids and their compositions in their greater context within our Solar System and beyond.Comment: Accepted chapter in Asteroids IV in the Space Science Series to be published Fall 201