Made in America? The New World, the Old, and the Industrial Revolution

For two decades, the consensus explanation of the British Industrial Revolution has placed technological change and the supply side at center stage, affording little or no role for demand or overseas trade. Recently, alternative explanations have placed an emphasis on the importance of trade with New World colonies, and the expanded supply of raw cotton it provided. We test both hypotheses using calibrated general equilibrium models of the British economy and the rest of the world for 1760 and 1850. Neither claim is supported. Trade was vital for the progress of the industrial revolution; but it was trade with the rest of the world, not the American colonies, that allowed Britain to export its rapidly expanding textile output and achieve growth through extreme specialization in response to shifting comparative advantage.

Electrons in image states near roughened metal surfaces

Electrons near roughened Ag and Au surfaces with chemisorbed dielectric overlayers of alkanethiol or alkaneselenol self-assembled monolayers are shown to move within the sulfur or selenium head-group layer on the metal terraces. The electrons exist in image states with respect to Ag or Au step edges. There is no substantial image force between the electrons and the terraces

Made in America? The New World, the Old, and the Industrial Revolution

For two decades, the consensus explanation of the British Industrial Revolution has placed technological change and the supply side at center stage, affording little or no role for demand or overseas trade. Recently, alternative explanations have placed an emphasis on the importance of trade with New World colonies, and the expanded supply of raw cotton it provided. We test both hypotheses using calibrated general equilibrium models of the British economy and the rest of the world for 1760 and 1850. Neither claim is supported. Trade was vital for the progress of the industrial revolution; but it was trade with the rest of the world, not the American colonies, that allowed Britain to export its rapidly expanding textile output and achieve growth through extreme specialization in response to shifting comparative advantage.

Handedness and schizotypy in a Japanese sample: an association masked by cultural effects on hand usage

Previous research has shown a robust association between schizotypy and mixed/ambiguous-handedness, but little is known about the universality of this relationship outside Western cultures. The present paper examines this issue in a sample of 413 Japanese students administered (in Japan) the Annett handedness questionnaire and a schizotypy scale (STA). Conventional analyses of current hand preference, using several indices derived from the Annett scale, mostly failed to replicate previous findings. However, there was a significant tendency for greater use of either hand in highly schizotypal males. Furthermore, a significant association between schizotypy and non-right-handedness was found—again only in males—after correcting for the effects of early switching of hand usage, presumed to be due to cultural pressure against left-handedness in Japanese society. These results were found to be highly convergent with findings previously reported for clinical schizophrenia

Heart-beat perception, panic/somatic symptoms and anxiety sensitivity in children

There is considerable evidence implicating heart-beat perception (HBP) accuracy and anxiety sensitivity (AS) in the development of panic in adults. However, to date there have been no studies exploring the association between HBP, AS and childhood panic/somatic symptoms. Seventy-nine children aged 8 to 11 years completed a mental tracking paradigm (Psychophysiology 18 (1981) 483) to assess HBP, the Children’s Anxiety Sensitivity Index (J Clin Chil Psychol 20 (1991) 162) and the Screen for Childhood Anxiety Related Emotional Disorders (J Am Acad Child Adoles Psych 38 (1999) 1230). Those with good HBP (n = 7, 9%) had significantly higher panic/somatic symptoms (t = -1.71, P < 0.05), and AS (t = -2.16, P < 0.02) than those with poor HBP. There were no effects of age, sex or BMI on HBP. Those with high levels of panic/somatic symptoms were seven times more likely to have good HBP and had AS scores 1 S.D. higher than the remainder of the sample. Multivariate analyses revealed that these two phenotypes had independent associations with high panic/somatic symptoms. These results extend the literature on HBP and panic and suggest that in children, as in adults, increased panic/somatic symptoms are associated with enhanced ability to perceive internal physiological cues, and fear of such sensations

Cyclical behaviour and disc truncation in the Be/X-ray binary A0535+26

A0535+26 is shown to display quantised IR excess flux states, which are interpreted as the first observational verification of the resonant truncation scheme proposed by Okazaki and Negueruela (2001) for BeXRBs. The simultaneity of X-ray activity with transitions between these states strongly suggests a broad mechanism for outbursts, in which material lost from the disc during the reduction of truncation radius is accreted by the NS. Furthermore changes between states are shown to be governed by a 1500 day period, probably due to precession of the Be disc, which profoundly dictates the global behaviour of the system. Such a framework appears to be applicable to BeXRBs in general.Comment: 10 pages, 11 figs, submitted to MNRA

Monitoring Base Specific Dynamics during Melting of DNA-Ligand Complexes using Temperature-Jump Time-Resolved Infrared Spectroscopy

Ultrafast time-resolved infrared spectroscopy employing nanosecond temperature-jump initiation has been used to study the melting of double-stranded (ds)DNA oligomers in the presence and absence of minor groove-binding ligand Hoechst 33258. Ligand binding to ds(5′-GCAAATTTCC-3′), which binds Hoechst 33258 in the central A-tract region with nanomolar affinity, causes a dramatic increase in the timescales for strand melting from 30 to 250 μs. Ligand binding also suppresses premelting disruption of the dsDNA structure, which takes place on 100 ns timescales and includes end-fraying. In contrast, ligand binding to the ds(5′-GCATATATCC-3′) sequence, which exhibits an order of magnitude lower affinity for Hoechst 33258 than the A-tract motif, leads to an increase by only a factor of 5 in melting timescales and reduced suppression of premelting sequence perturbation and end-fraying. These results demonstrate a dynamic impact of the minor groove ligand on the dsDNA structure that correlates with binding strength and thermodynamic stabilization of the duplex. Moreover, the ability of the ligand to influence base pairs distant from the binding site has potential implications for allosteric communication mechanisms in dsDNA