2,572 research outputs found

    Maps for Electron Clouds: Application to LHC Conditioning

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    In this communication we present a generalization of the map formalism, introduced in [1] and [2], to the analysis of electron flux at the chamber wall with particular reference to the exploration of LHC conditioning scenarios.Comment: 3 pages, 4 figure

    Mothers and fathers with Binge Eating Disorder and their 18-36 months old children: a longitudinal study on parent-infant interactions and offspring\u2019s emotional-behavioral profiles

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    Maternal Binge Eating Disorder (BED) has been suggested to be associated with poor parent\u2013infant interactions during feeding and with children\u2019s emotional and behavioral problems during infancy (Blissett and Haycraft, 2011). The role of fathers has received increasing consideration in recent years, yet the research has not focused on interactional patterns between fathers with BED and their children. The present study aimed to longitudinally investigate the in\ufb02uence of BED diagnosis, in one or both parents, on parent\u2013infant feeding interactions and on children\u2019s emotional\u2013behavioral functioning. 612 subjects (408 parents; 204 children), recruited in mental health services and pre-schools in Central Italy, were divided into four groups: Group 1 included families with both parents diagnosed with BED, Group 2 and 3 included families with one parent diagnosed with BED, Group 0 was a healthy control. The assessment took place at T1 (18 months of age of children) and T2 (36 months of age of children): feeding interactions were assessed through the Scale for the Assessment of Feeding Interactions (SVIA) while child emotional\u2013behavioral functioning was evaluated with the Child Behavior Check-List (CBCL). When compared to healthy controls, the groups with one or both parents diagnosed with BED showed higher scores on the SVIA and on the CBCL internalizing and externalizing scales, indicating poorer adult\u2013child feeding interactions and higher emotional\u2013behavioral dif\ufb01culties. A direct in\ufb02uence of parental psychiatric diagnosis on the quality of mother\u2013infant and father\u2013infant interactions was also found, both at T1 and T2. Moreover, dyadic feeding interactions mediated the in\ufb02uence of parental diagnosis on children\u2019s psychological functioning. The presence of BED diagnosis in one or both parents seems to in\ufb02uence the severity of maladaptive parent\u2013infant exchanges during feeding and offspring\u2019s emotional\u2013behavioral problems over time, consequently affecting different areas of children\u2019s psychological functioning. This is the \ufb01rst study to demonstrate the speci\ufb01c effects of maternal and paternal BED on infant development. These results could inform prevention and intervention programs in families with one or both parents diagnosed with BED

    Does alexithymia have a mediating effect between impulsivity and emotional-behavioral functioning in adolescents with binge eating disorder?

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    Objective: Binge eating Disorder (BeD) has recently been included in the Dsm-5. like many other eating disorder symptoms, BED is often present in adolescence. No studies have specifically investigated the influence of impulsivity and alexithymia on the emotional-behavioural functioning of adolescents diagnosed with BeD. Method: in this study, we recruited n = 162 adolescents (age range: 14-18) and divided them into two groups: 78 adolescents diagnosed with BeD, according to the Dsm-5 criteria (group A), and 84 healthy controls (group B). participants completed the youth self-report (ysr/11-18), the toronto Alexithymia scale (tAs-20) and the Barratt impulsiveness scale (Bis-11). Results: the results showed that group A had higher scores of alexithymia, impulsivity and maladaptive emotionalbehavioural functioning than Group B. Furthermore, alexithymia had a mediating effect on the relationship between impulsivity and emotional-behavioural functioning. Conclusions: These results allow us to hypothesise that alexithymia is a key variable influencing the emotional and behavioural problems of adolescents affected by BED. Our data confirms the previous studies underlining the association of impulsivity and alexithymia with the diagnosis of BeD in adolescents, and our study contributes to the previous literature, emphasising the central role of alexithymia in the mediating effect between impulsivity and emotional and behavioural problems. these results suggest the importance of promoting prevention and treatment polices focused on alexithymia

    An Early Presenting Esophageal Schwannoma

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    Esophageal schwannoma is a rare diagnosis and historically has been a tumor of middle-aged females. We report a case of a 22-year-old male presenting initially with dyspnea secondary to tracheal compression from an 8 × 6 × 3.0 cm esophageal schwannoma. The tumor was surgically resected, and diagnosis was confirmed with immunohistochemical and pathological studies. We report the youngest case of esophageal schwannoma in an otherwise healthy individual

    Atmospheric Reentry Dynamics of Conic Objects

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    One of the key issues in a reentry risk analysis is the calculation of the aerodynamic coefficients. This paper presents a methodology to obtain these coefficients and couple it to a code that computes re-entry trajectories considering six degrees of freedom. To evaluate the different flight conditions encountered during the natural re-entry of conical objects, the Euler Equations for gasdynamics flows are used. A new scheme TVD (Total Variation Diminishing) is incorporated to a finite volume unstructured cell-centred formulation, for application to three-dimensional Euler flows. Finally, numerical results are obtained for a conical body at different attack angles and Mach. With these results, the calculation of the trajectories during atmospheric re-entry is completed

    Identification of human intestinal parasites affecting an asymptomatic peri-urban Argentinian population using multi-parallel quantitative real-time polymerase chain reaction

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    Background: In resource-limited countries, stool microscopy is the diagnostic test of choice for intestinal parasites (soil-transmitted helminths and/or intestinal protozoa). However, sensitivity and specificity is low. Improved diagnosis of intestinal parasites is especially important for accurate measurements of prevalence and intensity of infections in endemic areas. Methods: The study was carried out in OrĂĄn, Argentina. A total of 99 stool samples from a local surveillance campaign were analyzed by concentration microscopy and McMaster egg counting technique compared to the analysis by multi-parallel quantitative real-time polymerase chain reaction (qPCR). This study compared the performance of qPCR assay and stool microscopy for 8 common intestinal parasites that infect humans including the helminths Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Trichuris trichiura, and the protozoa Giardia lamblia, Cryptosporidium parvum/hominis, and Entamoeba histolytica, and investigated the prevalence of polyparasitism in an endemic area. Results: qPCR showed higher detection rates for all parasites as compared to stool microscopy except T. trichiura. Species-specific primers and probes were able to distinguish between A. duodenale (19.1 %) and N. americanus (36.4 %) infections. There were 48.6 % of subjects co-infected with both hookworms, and a significant increase in hookworm DNA for A. duodenale versus N. americanus (119.6 fg/ÎŒL: 0.63 fg/ÎŒL, P∈<∈0.001) respectively. qPCR outperformed microscopy by the largest margin in G. lamblia infections (63.6 % versus 8.1 %, P∈<∈0.05). Polyparasitism was detected more often by qPCR compared to microscopy (64.7 % versus 24.2 %, P∈<∈0.05). Conclusions: Multi-parallel qPCR is a quantitative molecular diagnostic method for common intestinal parasites in an endemic area that has improved diagnostic accuracy compared to stool microscopy. This first time use of multi-parallel qPCR in Argentina has demonstrated the high prevalence of intestinal parasites in a peri-urban area. These results will contribute to more accurate epidemiological survey, refined treatment strategies on a public scale, and better health outcomes in endemic settings.Fil: Cimino, RubĂ©n Oscar. Universidad Nacional de Salta; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Jeun, Rebecca. Baylor College Of Medicine; Estados UnidosFil: Juarez, Marisa. Universidad Nacional de Salta; ArgentinaFil: Cajal, Pamela S.. Universidad Nacional de Salta; ArgentinaFil: Vargas Flores, Paola Andrea. Universidad Nacional de Salta; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: EchazĂș, Adriana. Universidad Nacional de Salta; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Bryan, Patricia E.. Baylor College Of Medicine; Estados UnidosFil: Nasser, Julio RubĂ©n. Universidad Nacional de Salta; ArgentinaFil: Krolewiecki, Alejandro Javier. Universidad Nacional de Salta; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Mejia, Rojelio. Baylor College Of Medicine; Estados Unidos. Universidad Nacional de Salta; Argentin

    Suggestive hypothesis on a case report: Patient presenting with cyclical ovarian cysts coupled to increased cholestatic enzymes

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    We describe the case of a childbearing-age woman presenting with spontaneous recurrent functional ovarian cysts and, more interestingly, chronic and asymptomatic elevation of cholestatic parameters. The patient showed no history of chronic viral infections, immunological and metabolic disorders, alcohol abuse and environmental toxins exposition. Hepatic ultrasonography and cholangio-pancreatography-magnetic-resonance excluded any morphological and structural abnormalities, while liver biopsy evidenced only minimal and not specific features of inflammation. Cholestasis indices obtained prompt recovery after each cycle of synthetic hormone therapy, implanted to treat functional ovarian cysts. She has continuously experienced the off-therapy asynchronous recurrence of liver laboratory abnormalities and functional ovarian cysts. The favorable effect of the synthetic hormone therapy to obtaining a stable recovery of this unexplained long-lasting cholestatic syndrome could be likely explained by downregulation of an endogenous ovarian overproduction, although estrogen-regulated local intracellular transduction pathways cannot be excluded

    Three Phenolic and a Sterol Glycosides Identified for the First Time in Matthiola longipetala Growing in Tunisia

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    Three phenolic glycosides: 4-O-ß-D-glycopyranosyl zingerone 1, 4-O-ß-D-glycopyranosylhomovanillyl alcohol 2 and eugenol glycoside 3, together with 3-O-ß-D-glycopyranosyl sitosterol 4, were isolated and identified for the first time from the flowers of Matthiola longipetala (Crucifers) growing in Tunisia. The structures of 1, 2 and 3 were identified via their acetylated derivatives on the basis of the 1 and 2D NMR data analysis, mass spectrometry and IR spectroscopy

    Experimental observation of optical rotation generated in vacuum by a magnetic field

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    We report the experimental observation of a light polarization rotation in vacuum in the presence of a transverse magnetic field. Assuming that data distribution is Gaussian, the average measured rotation is (3.9+/-0.5)e-12 rad/pass, at 5 T with 44000 passes through a 1m long magnet, with lambda = 1064 nm. The relevance of this result in terms of the existence of a light, neutral, spin-zero particle is discussed.Comment: 11 pages, 4 figures, submitted to Physical Review Letters Comment to version 2: minor changes to abstract and final discussion. Added 2 references Comment to version 3: corrected minor typographical errors, eliminated the distinction between scalar and pseudoscalar in the particle interpretation of the resul
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