Nasal Manifestations of Systemic Disease

Nasal manifestations of systemic diseases can involve the nose and paranasal sinuses. Sinonasal symptoms can often be seen early in the disease process. Recognizing these symptoms and making early diagnoses are the key to deciding on the treatment approach to the presented sinonasal issue as well as systemic therapy. Disorders can vary, from granulomatous processes to immunodeficiencies diseases. Wegener\u27s granulomatosis is a systemic chronic vasculitis of small and medium-sized blood vesels, with an autoimmune component. The disease may appear in the localised form (confirned to the upper respiratory region) or in the disseminated form (pulmonary involvement and focal glomerulonephritis in the kidneys). Churg-Strauss syndrome or eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotizing vasculitis that affects small-to-medium-size vessels and is associated with severe asthma and blood and tissue eosinophilia. There are three general phases: I. allergic phase by asthma and sinusitis, II. eosinophilic phase by peripheral hyperoesiophilia and intraorgan infiltration of eosinophils and III. vasculitis phase by necrotising inflammation of small vessels and end-organ damage. Syndrome Sjögren is a chronic autoimmune disease characterized by damage to and dysfunction of the exocrine glands, specifically the salivary and lacrimal glands, mediated by autoantibodies and lymphocytic infiltrates, resulting in dry eyes and mouth

Ultradilute quantum liquid drops

Using quantum Monte Carlo methods we have studied dilute Bose-Bose mixtures with attractive interspecies interaction in the limit of zero temperature. The calculations are exact within some statistical noise and thus go beyond previous perturbative estimations. By tuning the intensity of the attraction, we observe the evolution of an $N$-particle system from a gas to a self-bound liquid drop. This observation agrees with recent experimental findings and allows for the study of an ultradilute liquid never observed before in Nature.Comment: 5 pages, 5 figure

Cigarette Smoking and Progression of Laryngeal Lesions

The association between cigarette smoking and an increased risk of laryngeal carcinoma has been demonstrated in numerous studies. The aim of the present study was to assess the prevalence of smoking habit in patients with different laryngeal pathologies. The prevalence of cigarette smoking was compared between patients with laryngeal tumors and those with nonmalignant laryngeal lesions. Data on all patients with indications for direct microlaryngoscopy at the Clinic for Otorhinolaryngology of the University Hospital Center Split, during a five-year period were analyzed. The study included 562 patients with various laryngeal pathologies, divided into three groups as follows: group 1, benign lesions; group 2, precancerous lesions; and group 3, tumors. The majority of patients (82.92%) had a long history of smoking. The proportion of smokers was lowest in benign lesion group (72.13%), higher in precancerous lesion group (81.48%) and highest in malignant lesion group (97.14%). There was a statistically significant difference in the prevalence of cigarette smoking between patients with laryngeal tumors and those with benign or precancerous lesions (p<0.001). The mean number of cigarettes per day was 20.54±14.80, and was lowest in benign lesion group (15.67±13.41) and highest in malignant lesion group (26.33±12.70). The mean length of smoking habit was 26.44±16.92 years, ranging from 19.57±16.03 years in benign lesion group to 35.20±12.12 years in malignant lesion group. Study results clearly pointed to the increased prevalence of laryngeal diseases in smokers, with a significant difference between patients with benign laryngeal lesions and those with laryngeal tumors

Automatic Regulation of Ship Manoeuvring Using 2nd Order Nomoto Model

Danas, u svakodnevnom životu su neizbježni sustavi automatskog upravljanja tj. sustavi automatske regulacije. Automatska regulacija kursa broda omogućuje ekonomičnu, pouzdanu i kvalitetnu plovidbu uz olakšano radno opterećenje posade. Upravljanje brodom pomoću autopilota jedna je od najranijih primjena teorije automatskog upravljanja. Zahtjev za primjenu sofisticiranijih autopilota za upravljanje brodom uglavnom je rezultat želje za uštedom goriva i poboljšanjima performansi. Budući da su jednadžbe kretanja broda vrlo nelinearne, a parametri modela ovise o brzini kretanja i vremenskim uvjetima, treba uzeti u obzir teoriju nelinearne kontrole. Međutim, pokazuje se da kod konstrukcije autopilota kod upravljanja s kursom broda, sasvim dovoljno je koristiti Nomotov model broda prvog reda. U radu će se prikazati način ugađanja parametara PID regulatora kod upravljanja s kursom broda, vodeći računa o realnim parametrima broda.Today, in everyday life, there are inevitable automatic control systems. The automatic regulation of the boat's course enables economical, reliable and high quality navigation with easy crew load. The management of a ship by autopilot is one of the earliest applications of automated control theory. The application for more sophisticated autopilots for ship management is mainly due to the desire to save fuel and improve performance. Since ship motion equations are non-linear, and model parameters depend on the speed of movement and the weather conditions, the theory of nonlinear control should be taken into account. It is, however, shown that in the construction of the autopilot when managing a ship's course, it is quite enough to use Nomoto's first-order ship model. This paper will show how to adjust the PID regulator parameters when managing the course of the ship, taking into account the real parameters of the ship

Finite-range effects in ultradilute quantum drops

In the first experimental realization of dilute Bose-Bose liquid drops using two hyperfine states of $^{39}$K some discrepancies between theory and experiment were observed. The standard analysis of the data using the Lee-Huang-Yang beyond mean-field theory predicted critical numbers which were significantly off the experimental measurements. Also, the radial size of the drops in the experiment proved to be larger than expected from this theory. Using a new functional, which is based on quantum Monte Carlo results of the bulk phase incorporating finite-range effects, we can explain the origin of the discrepancies in the critical number. This result proves the necessity of including finite-range corrections to deal with the observed properties in this setup. The controversy on the radial size is reasoned in terms of the departure from the optimal concentration ratio between the two species of the mixture

Kvantne Monte-Carlo simulacije dvokomponentnih bozonskih mješavina

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