1 research outputs found
Nucleophilic versus electrophilic boryl moieties: activation and application in catalysis
Els compostos de bortrivalent s’han considerat tradicionalment com a Ă cids de Lewis, preferint acceptar electrons mĂ©s que donar-los en el curs de les reaccions, peròdarrerament han sorgit exemples a la bibliografia on el compost trivalent de bor presenta una reactivitat insòlita vers posicions electrofĂliques. Aquest fet ens suggereix un nou context nucleofĂlic per als sintonsboril, que pot ser augmentat depenent dels substituents als quals estigui unit el bor. En aquesta tesi, volem mostrar una visiĂł de les reactivitat soposades mitjançantl’estudi teòric de diferents compostos de bortri coordinats. A mĂ©s a mĂ©s tambĂ© ens hem centrat en l’estudi de dues reaccions, la hidroboraciĂł trans no convencional on la unitat borilactuacom a electròfil i la -boraciĂł organo catalĂtica amb un diborĂ mixton la unitat boril actua com a nucleòfil.Boron compounds have been traditionally regarded as “Lewis Acids” preferring to accept electrons rather than donate them in the course of their reactions, but current examples of unusual reactivity between tricoordinatedboranes and electrophilic sites suggest another conceptual context for the boryl moieties, based on their nucleophilic character which can be enhanced depending on the substituents on boron. In this thesis, we aim to show an overview of these opposite reactivities through the computational study of different trivalent boron compounds. Moreover, we have also focused our attention in the study of two reactions, the non-conventional trans-hydroboration where the boryl moiety is acting as an electrophile and the organocatalytic-boration with a mixed diboron reagent where the boryl moiety is acting as a nucleophile