4 research outputs found
Single-ion Kondo Scaling of the Coherent Fermi Liquid Regime in Ce1-xLaxNi2Ge2
Thermodynamic and transport properties of the La-diluted Kondo lattice
CeNi2Ge2 were studied in a wide temperature range. The Ce-rich alloys
Ce1-xLaxNi2Ge2 were found to exhibit distinct features of the coherent heavy
Fermi liquid. At intermediate compositions (0.7 <= x <= 0.9) non-Fermi liquid
properties have been observed, followed by the local Fermi liquid behavior in
the dilute limit. The 4f-electron contribution to the specific heat was found
to follow the predictions of the Kondo impurity model both in the local as well
as coherent regimes, with the characteristic Kondo temperature decreasing
rapidly from about 30 K for the parent compound CeNi2Ge2 to about 1K in the
most dilute samples. The specific heat does not show any evidence for the
emergence of a new characteristic energy scale related to the formation of the
coherent Kondo lattice.Comment: to appear in Physical Review Letter
Temperature Dependence of the Lower Critical Field of the Noncentrosymmetric Superconductor <i>α</i> ‐BiPd
International audienceTemperature variation of the lower critical H c1 field in the noncentrosymmetric superconductor α-BiPd is probed by local magnetization measurements using Hall micromagnetometry, performed down to 0.3 K in a magnetic field applied along the crystallographic b axis. Below a critical temperature T c ≃ 3.8 K, a conventional H c1 ðTÞ dependence is found, typical for a single-band s-wave superconductor. The obtained data imply an absence of spin-triplet component in the superconducting wavefunction and marginal multiband effects in this material, which contradicts some literature reports
Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation
Deregulated melanogenesis is involved in melanomagenesis and melanoma progression and resistance to therapy. Vitamin D analogs have anti-melanoma activity. While the hypercalcaemic effect of the active form of Vitamin D (1,25(OH)2D3) limits its therapeutic use, novel Vitamin D analogs with a modified side chain demonstrate low calcaemic activity. We therefore examined the effect of secosteroidal analogs, both classic (1,25(OH)2D3 and 25(OH)D3), and novel relatively non-calcemic ones (20(OH)D3, calcipotriol, 21(OH)pD, pD and 20(OH)pL), on proliferation, colony formation in monolayer and soft-agar, and mRNA and protein expression by melanoma cells. Murine B16-F10 and hamster Bomirski Ab cell lines were shown to be effective models to study how melanogenesis affects anti-melanoma treatment. Novel Vitamin D analogs with a short side-chain and lumisterol-like 20(OH)pL efficiently inhibited rodent melanoma growth. Moderate pigmentation sensitized rodent melanoma cells towards Vitamin D analogs, and altered expression of key genes involved in Vitamin D signaling, which was opposite to the effect on heavily pigmented cells. Interestingly, melanogenesis inhibited ligand-induced Vitamin D receptor translocation and ligand-induced expression of VDR and CYP24A1 genes. These findings indicate that melanogenesis can affect the anti-melanoma activity of Vitamin D analogs in a complex manner