52 research outputs found
On Explicit Probability Densities Associated with Fuss-Catalan Numbers
In this note we give explicitly a family of probability densities, the
moments of which are Fuss-Catalan numbers. The densities appear naturally in
random matrices, free probability and other contexts.Comment: 4 page
Wave diffraction of a hybrid wind turbine foundation with a double-layer aquaculture cage
A hybrid wind turbine foundation combined with a double-layer offshore net cage for marine aquaculture is proposed in this paper. To study the diffraction and hydrodynamic loads on the structure for waves with small steepness, a numerical model was established using linear potential theory and solved using the eigenfunction expansion method. A porosity parameter was introduced to describe the hydrodynamic characteristics of the net panels. The model was validated based on existing numerical results and experimental data. An empirical formula was derived to calculate the porosity parameter based on the opening ratios of the nets. The wavefield and wave force were calculated and analyzed by setting different porosity parameters, spacings between the exterior net and interior net, radius ratios of the exterior net to the wind turbine tower and thicknesses of the friction wheel. Noticeable differences in the wave elevation were observed between the upstream and downstream sides of the nets. At downstream sites, the wavefield exhibits different profiles, particularly for structures with low porosities. Sloshing modes were observed that impacted the force and wave elevation at certain frequencies. For the common fishing nets with large porosities, the spacing between the nets does not have a significant impact on the wavefield and wave force acting on the structure. Moreover, the radius and thickness of the friction wheel have a non-negligible influence on the force acting on the structure, which also narrows the intervals between adjacent sloshing frequencies. In summary, this study provides a perspective for the engineering design and hydrodynamic analysis of a hybrid wind turbine foundation with a double-layer aquaculture cage
A pyroptosis-related gene signature for prognosis prediction in hepatocellular carcinoma
IntroductionHepatocellular carcinoma (HCC) is one of the most invasive cancers with a low 5-year survival rate. Pyroptosis, a specialized form of cell death, has shown its association with cancer progression. However, its role in the prognosis of HCC has not been fully understood.MethodsIn our study, clinical information and mRNA expression for 1076 patients with HCC were obtained from the five public cohorts. Pyroptotic clusters were generated by unsupervised clustering based on 40 pyroptosis-related genes (PRGs) in the TCGA and ICGC cohort. A pyroptosis-related signature was constructed using least absolute shrinkage and selection operator (LASSO) regression according to differentially expressed genes (DEGs) of pyroptotic clusters. The signature was then tested in the validation cohorts (GES10142 and GSE14520) and subsequently validated in the CPTAC cohort (n=159) at both mRNA and protein levels. Response to sorafenib was explored in GSE109211.ResultsThree clusters were identified based on the 40 PRGs in the TCGA cohort. A total of 24 genes were selected based on DEGs of the above three pyroptotic clusters to construct the pyroptotic risk score. Patients with the high-risk score showed shorter overall survival (OS) compared to those with the low-risk score in the training set (P<0.001; HR, 3.06; 95% CI, 2.22-4.24) and the test set (P=0.008; HR, 1.61; 95% CI, 1.13-2.28). The predictive ability of the risk score was further confirmed in the CPTAC cohort at both mRNAs (P<0.001; HR, 2.99; 95% CI, 1.67-5.36) and protein levels (P<0.001; HR, 2.97; 95% CI 1.66-5.31). The expression of the model genes was correlated with immune cell infiltration, angiogenesis-related genes, and sensitivity to antiangiogenic therapy (P<0.05).DiscussionIn conclusion, we established a prognostic signature of 24 genes based on pyroptosis clusters for HCC patients, providing insight into the risk stratification of HCC
Storm impacts on phytoplankton community dynamics in lakes
In many regions across the globe, extreme weather events, such as storms, have increased in frequency, intensity and duration. Ecological theory predicts that such extreme events should have large impacts on ecosystem structure and function. For lake ecosystems, high winds and rainfall associated with storms are linked by short term runoff events from catchments and physical mixing of the water column. Although we have a well-developed understanding of how such wind and precipitation events alter lake physical processes, our mechanistic understanding of how these short-term disturbances 48 translate from physical forcing to changes in phytoplankton communities is poor. Here, we provide a conceptual model that identifies how key storm features (i.e., the frequency, intensity, and duration of wind and precipitation) interact with attributes of lakes and their watersheds to generate changes in a lake’s physical and chemical environment and subsequently phytoplankton community structure and dynamics. We summarize the current understanding of storm-phytoplankton dynamics, identify knowledge gaps with a systematic review of the literature, and suggest future research directions by generating testable hypotheses across a global gradient of lake types and environmental conditions.Fil: Stockwell, Jason D.. University of Vermont; Estados UnidosFil: Adrian, Rita. Leibniz Institute of Freshwater Ecology and Inland Fisheries; AlemaniaFil: Andersen, Mikkel. Dundalk Institute of Technology; IrlandaFil: Anneville, Orlane. Institut National de la Recherche Agronomique; FranciaFil: Bhattacharya, Ruchi. University of Missouri; Estados UnidosFil: Burns, Wilton G.. University of Vermont; Estados UnidosFil: Carey, Cayelan C.. Virginia Tech University; Estados UnidosFil: Carvalho, Laurence. Freshwater Restoration & Sustainability Group; Reino UnidoFil: Chang, ChunWei. National Taiwan University; RepĂşblica de ChinaFil: De Senerpont Domis, Lisette N.. Netherlands Institute of Ecology; PaĂses BajosFil: Doubek, Jonathan P.. University of Vermont; Estados UnidosFil: Dur, GaĂ«l. Shizuoka University; JapĂłnFil: Frassl, Marieke A.. Griffith University; AustraliaFil: Gessner, Mark O.. Leibniz Institute of Freshwater Ecology and Inland Fisheries; AlemaniaFil: Hejzlar, Josef. Biology Centre of the Czech Academy of Sciences; RepĂşblica ChecaFil: Ibelings, Bas W.. University of Geneva; SuizaFil: Janatian, Nasim. Estonian University of Life Sciences; EstoniaFil: Kpodonu, Alfred T. N. K.. City University of New York; Estados UnidosFil: Lajeunesse, Marc J.. University of South Florida; Estados UnidosFil: Lewandowska, Aleksandra M.. Tvarminne Zoological Station; FinlandiaFil: Llames, Maria Eugenia del Rosario. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Instituto de Investigaciones BiotecnolĂłgicas. Universidad Nacional de San MartĂn. Instituto de Investigaciones BiotecnolĂłgicas; ArgentinaFil: Matsuzaki, Shin-ichiro S.. National Institute for Environmental Studies; JapĂłnFil: Nodine, Emily R.. Rollins College; Estados UnidosFil: Nõges, Peeter. Estonian University of Life Sciences; EstoniaFil: Park, Ho-Dong. Shinshu University; JapĂłnFil: Patil, Vijay P.. US Geological Survey; Estados UnidosFil: Pomati, Francesco. Swiss Federal Institute of Water Science and Technology; SuizaFil: Rimmer, Alon. Kinneret Limnological Laboratory; IsraelFil: Rinke, Karsten. Helmholtz-Centre for Environmental Research; AlemaniaFil: Rudstam, Lars G.. Cornell University; Estados UnidosFil: Rusak, James A.. Ontario Ministry of the Environment and Climate Change; CanadáFil: Salmaso, Nico. Research and Innovation Centre - Fondazione Mach; ItaliaFil: Schmitt, François. Laboratoire d’OcĂ©anologie et de GĂ©osciences; FranciaFil: Seltmann, Christian T.. Dundalk Institute of Technology; IrlandaFil: Souissi, Sami. Universite Lille; FranciaFil: Straile, Dietmar. University of Konstanz; AlemaniaFil: Thackeray, Stephen J.. Lancaster Environment Centre; Reino UnidoFil: Thiery, Wim. Vrije Unviversiteit Brussel; BĂ©lgica. Institute for Atmospheric and Climate Science; SuizaFil: Urrutia Cordero, Pablo. Uppsala University; SueciaFil: Venail, Patrick. Universidad de Ginebra; SuizaFil: Verburg, Piet. 8National Institute of Water and Atmospheric Research; Nueva ZelandaFil: Williamson, Tanner J.. Miami University; Estados UnidosFil: Wilson, Harriet L.. Dundalk Institute of Technology; IrlandaFil: Zohary, Tamar. Israel Oceanographic & Limnological Research; IsraelGLEON 20: All Hands' MeetingRottnest IslandAustraliaUniversity of Western AustraliaUniversity of AdelaideGlobal Lake Ecological Observatory Networ
Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group
Axial Compressive Behavior of Steel-Damping-Concrete Composite Wall
This paper presents a novel steel-damping-concrete (SDC) composite wall as a vertical element for high-rise buildings and nuclear power plants etc. In an SDC composite wall, a damping layer is sandwiched between the concrete core and steel plates to reduce structural response based on its damping characteristics under axial and seismic loads. To ensure that an SDC composite wall exhibits a comparable compressive resistance as a steel-concrete-steel (SCS) composite wall, two types of reinforcing approaches including steel sheets and sleeves are utilized to enhance the weakness of the damping layer on the concrete core. The compressive performance of the reinforced SDC composite wall is numerically and analytically investigated using finite element (FE) simulations by ABAQUS. The influences of several key parameters including the type of reinforcement, the thickness of the damping layer, steel plates, and concrete core, the binding bar spacing as well as the diameter of steel sheets on the compressive performance of the composite walls are investigated through numerical analyses. The results show that while only embedding the rubber interlayer in the composite wall leads to the decrease of compressive resistance of the composite wall, the steel sheets and sleeves can provide the confinement effect on concrete core efficiently and improve the compressive resistance and ductility of walls. Based on the available methods in the current design codes such as Eurocode 4, AISC-360, a theoretical model is developed to predict the ultimate compressive resistance of SDC walls. The predictions show a reasonable correlation when compared with the numerical results
Advances in Cathode Materials for High-Performance Lithium-Sulfur Batteries
Lithium-sulfur batteries (LSBs) represent a promising energy storage technology, and they show potential for next-generation high-energy systems due to their high specific capacity, abundant constitutive resources, non-toxicity, low cost, and environment friendliness. Unlike their ubiquitous lithium-ion battery counterparts, the application of LSBs is challenged by several obstacles, including short cycling life, limited sulfur loading, and severe shuttling effect of polysulfides. To make LSBs a viable technology, it is very important to design and synthesize outstanding cathode materials with novel structures and properties. In this review, we summarize recent progress in designs, preparations, structures, and properties of cathode materials for LSBs, emphasizing binary, ternary, and quaternary sulfur-based composite materials. We especially highlight the utilization of carbons to construct sulfur-based composite materials in this exciting field. An extensive discussion of the emerging challenges and possible future research directions for cathode materials for LSBs is provided. : Inorganic Chemistry; Electrochemical Energy Storage; Energy Materials Subject Areas: Inorganic Chemistry, Electrochemical Energy Storage, Energy Material
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