Development of lower limb rehabilitation evaluation system based on virtual reality technology

Nowadays, with the development of the proportion of the elderly population in the world, several problems caused by the population aging gradually into people's horizons. One of the biggest problems plagued the vast majority of the elderly is hemiplegia, which leads to the vigorous development of the physical therapists. However, these traditional methods of physical therapy mainly rely on the skill of the physical therapists. In order to make up the defects of traditional methods, many research groups have developed different kinds of robots for lower limb rehabilitation training but most of them can only realize passive training which cannot adopt rehabilitation training based on the patients' individual condition effectively and they do not have a rehabilitation evaluation system to assess the real time training condition of the hemiplegic patients effectively. In order to solve the problems above, this paper proposed a lower limb rehabilitation evaluation system which is based on the virtual reality technology. This system has an easy observation of the human-computer interaction interface and the doctor is able to adjust the rehabilitation training direct at different patients in different rehabilitation stage based on this lower limb rehabilitation evaluation system. Compared with current techniques, this novel lower limb rehabilitation evaluation system is expected to have significant impacts in medical rehabilitation robot field

The Role of Thyroid Transcription Factor-1 DNA Binding Activity in Lung Cancer

Background and objective TTF-1 is a homeodomain transcriptional regulator of both structural organization of the lung and differentiation of highly specialized epithelial cell types such as alveolar typeⅡcells. This study is to investigate the Thyroid transcription factor-1 (TTF-1) DNA binding activity in lung cancer tissue and its significance with lung cancer pathologic type and differentiation level. Methods The TTF-1 DNA binding activity wasdetected in lung cancer tissue by Electrophoretic mobility shift assay (EMSA), autoradiography and photo densitometry. Results The optical density of TTF-1 DNA binding activity in adenocarcinoma tissue was 172±23.2 and it was remarkably higher than that in other pathological types, including 141±16.3 of small cell carcinomas and 122±13.6 of squamous carcinoma (P <0.05). The optical density of TTF-1 DNA binding activity in highly differentiated lung cancer tissues was significantly higher than that in poor-differentiated lung cancer (P <0.05). Overall survival and disease-free survival rates were better among patients with low TTF-1 DNA binding activity levels than those in patients with high levels. Conclusion TTF-1 DNA binding activity is a potential predictor of lung cancer metastasis and survival

Motion Retargeting for the Hand Gesture

This paper presents a new technique for retargeting the sign language data captured from motion capture device to different characters with different sizes and proportions. Realistic and natural animations can be produced to express similar meanings to the original. The proposed method first defines many sensitive points on the human body and selects the key sensitive points through analyzing the importance of the sensitive points. Next a novel mapping method based on relative position is presented to adapt the original sensitive points to the target sensitive points. Finally we utilize an IK solver to realize the retargeting problem. Experimental results show that the proposed method dramatically improves the recognition rate about 30%