16 research outputs found
Properties of single-layer graphene doped by nitrogen with different concentrations
Graphene has vast promising applications on the nanoelectronics and
spintronics because of its unique magnetic and electronic properties. Making
use of an ab initio spin-polarized density functional theory, implemented by
the method of Heyd-Scuseria-Ernzerhof 06(HSE06) hybrid functional, the
properties of nitrogen substitutional dopants in semi-metal monolayer graphene
were investigated. We found from our calculation, that introducing nitrogen
doping would possibly break energy degeneracy with respect to spin(spin
symmetry breaking) at some doping concentrations with proper dopant
configurations. The spin symmetry breaking would cause spin-polarized effects,
which induce magnetic response in graphene. This paper systematically analyzed
the dependence of magnetic moments and band gaps in graphene on doping
concentrations of nitrogen atoms, as well as dopant configurations.Comment: 17pages,4figures,5table
Unified description of perturbation theory and band center anomaly in one-dimensional Anderson localization
We calculated numerically the localization length of one-dimensional Anderson
model with diagonal disorder. For weak disorder, we showed that the
localization length changes continuously as the energy changes from the band
center to the boundary of the anomalous region near the band edge. We found
that all the localization lengths for different disorder strengths and
different energies collapse onto a single curve, which can be fitted by a
simple equation. Thus the description of the perturbation theory and the band
center anomaly were unified into this equation.Comment: 10 pages, 6 figure
Size-dependent melting: Numerical calculations of the phonon spectrum
In order to clarify the relationship between the phonon spectra of
nanoparticles and their melting temperature, we studied in detail the
size-dependent low energy vibration modes. A minimum model with atoms on a
lattice and harmonic potentials for neighboring atoms is used to reveal a
general behavior. By calculating the phonon spectra for a series of
nanoparticles of two lattice types in different sizes, we found that density of
low energy modes increases as the size of nanoparticles decreases, and this
density increasing causes decreasing of melting temperature. Size-dependent
behavior of the phonon spectra accounts for typical properties of
surface-premelting and irregular melting temperature on fine scales. These
results show that our minimum model captures main physics of nanoparticles.
Therefore, more physical characteristics for nanoparticles of certain types can
be given by phonons and microscopic potential models.Comment: 5 pages, 5 figure
Localization behavior induced by asymmetric disorder for the one-dimensional Anderson model
Beads-on-String Structured Nanofibers for Smart and Reversible Oil/Water Separation with Outstanding Antifouling Property
Apolipoprotein C1 promotes tumor progression in gastric cancer
BACKGROUND: Gastric cancer (GC) is a malignancy with the worst prognosis that seriously threatens human health, especially in East Asia. Apolipoprotein C1 (apoc1) belongs to the apolipoprotein family. In addition, apoc1 has been associated with various tumors. However, its role in GC remains unclear. Methods: Firstly, we quantified its expression in GC and adjacent tumor tissues, using The Cancer Genome Atlas (TCGA). Next, we assessed cell invasion and migration abilities. Finally, we revealed the role of apoc1 in the tumor microenvironment (TME), immune cell infiltration and drug sensitivity. Results: Firstly, in TCGA database, it has been shown that elevated expression of apoc1 was identified in various cancers, including GC, then we found that high expression of apoc1 was significantly correlated with poor prognosis in GC. Histologically, apoc1 expression is proportional to grade, cancer stage, and T stage. The experimental results showed that apoc1 promoted cell invasion and migration. Then GO, KEGG, and GSEA pathway analyses indicated that apoc1 may be involved in the WNT pathway and immune regulation. Furthermore, we found out the tumor-infiltrating immune cells related to apoc1 in the tumor microenvironment (TME) using TIMER. Finally, we investigated the correlation between apoc1 expression and drug sensitivity, PD-1 and CTLA-4 therapy. Conclusions: These results suggest that apoc1 participates in the evolution of GC, and may represent a potential target for detection and immunotherapy in GC
Biomimetic Water-Collecting Fabric with Light-Induced Superhydrophilic Bumps
To
develop an efficient water-collecting surface that integrates both
fast water-capturing and easy drainage properties is of high current
interest for addressing global water issues. In this work, a superhydrophobic
surface was fabricated on cotton fabric via manipulation of both the
surface roughness and surface energy. This was followed by a subsequent
spray coating of TiO<sub>2</sub> nanosol that created light-induced
superhydrophilic bumps with a unique raised structure as a result
of the interfacial tension of the TiO<sub>2</sub> nanosol sprayed
on the superhydrophobic fiber surface. These raised TiO<sub>2</sub> bumps induce both a wettability gradient and a shape gradient, synergistically
accelerating water coalescence and water collection. The in-depth
study revealed that the quantity and the distribution of the TiO<sub>2</sub> had a significant impact on the final water collection efficiency.
This inexpensive and facilely fabricated fabric biomimicks the desert
beetleās back and spider silk, which are capable of fog harvesting
without additional energy consumption
CPXM1 correlates to poor prognosis and immune cell infiltration in gastric cancer
Background: Gastric cancer (GC) is the fourth most common cause of cancer-related death and the fifth most frequent malignant cancer, especially advanced GC. Carboxypeptidase X member 1 (CPXM1) is an epigenetic factor involved in many physiological processes, including osteoclast differentiation and adipogenesis. Several studies have shown the association of CPXM1 with multiple tumors; however, the mechanism of CPXM1 involvement in the progression of GC is yet to be characterized. Method: CPXM1 expression data were obtained from the Tumor Immune Estimation Resource. The Cancer Genome Atlas and the Gene Expression Omnibus databases were used to obtain patient-matched clinicopathological information, and the KaplanāMeier plot database was utilized for the prognosis analysis of GC patients. The Catalog of Somatic Mutations in Cancer and cBioportal databases were adopted to study CPXM1 mutations in tumors. Next, we utilized the Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Gene Set Enrichment Analysis for mechanism research. Furthermore, we performed tumor microenvironment and immune infiltration analysis based on CPXM1. Finally, we predicted sensitivity to several targeted drugs in GC patients based on CPXM1.CPXM1 is upregulated in GC and is correlated with poor prognosis, gender, and tumor stage in GC patients. Gene enrichment analysis suggested that CPXM1 may regulate the occurrence and progression of GC via the PI3KāAKT and TGF-Ī² pathway. Moreover, CPXM1 expression results in an increase in the proportion of immune and stromal cells. Additionally, the proportion of plasma cells was inversely related to the expression of CPXM1, whereas macrophage M2 expression was proportionate to CPXM1 expression. Finally, six small-molecule drugs that showed notable variations in IC50 between two groups were screened. Conclusion: These results suggested that CPXM1 regulates the progression of GC and may represent a novel target for the detection and treatment of GC