Progress of the special-subjects study on the construction of comprehensive geological disaster prevention and control system in Yunnan Province

The establishment of the comprehensive geological disaster prevention and control system in Yunnan province stands as China’s most extensive and grand-scale endeavor in safeguarding the prevention and control of geological disasters in China. Its implementation has led to a significant reduction in the occurrence of geological disasters, resulting in a substantial decrease in both casualties and missing persons affected by such disasters. This accomplishment has yielded remarkable outcomes in disaster prevention and mitigation. Based on the results of 12 series monographic studies, this paper provides an overview of the implementation of the system and its disaster prevention and mitigation effects. It summarizes the main scientific and technological achievements, with a particular focus on the causes and patterns of plateau geological disasters, understanding of special rock and soil disaster control mechanisms, susceptibility zoning evaluation, comprehensive remote sensing identification of geological hazards, progress in automated monitoring and early warning, and the development of geological environment information standard system. These achievements can provide valuable insights for the comprehensive geological disaster prevention and control in Yunnan Province

Use of Xinfeng capsule to treat abarticular pathologic changes in patients with rheumatoid arthritis

AbstractObjectiveTo observe the influence of Xinfeng-capsule (XFC) on abarticular pathologic changes (APCs) and other indices of patients with rheumatoid arthritis (RA) and explore the mechanism of action of XFC in improving such changes.MethodsThree-hundred RA patients were divided randomly into a treatment group (n=150) and control group (n=150). A normal control (NC) group (n=90) was also created. Changes in cardiac function, pulmonary function, anemia indices and platelet parameters of RA patients were measured. Curative effects of the two groups were compared, and comparison carried out with the NC group.ResultsIn 300 RA patients, late diastolic peak flow velocity (A peak) was much higher (P<0.01) and early diastolic peak flow velocity (E peak), E/A, and left ventricular fraction shortening much lower (P<0.01) than those in the NC group. Vital capacity (VC), forced vital capacity in one second, forced vital capacity (FVC), maximal voluntary ventilation (MVV), maximal expiratory flow in 50% of VC (FEF50) and FEF75 were lowered remarkably (P< 0.05 or P<0.01). Platelet count (PLT), plateletcrit (PCT) and mean platelet volume (MPV) increased markedly (P<0.05 or P<0.01), and hemoglobin (Hb) level decreased significantly (P<0.05). After XFC treatment, the A peak and PLT and PCT were much lower (P<0.05), and E/A and the number of red blood cells as well as Hb level were much higher (P< 0.05), as were FVC, MVV and FEF50 (P<0.05 or P< 0.01), in the treatment group than those in the NC group. Total score of pain and swelling in joints, uric-acid level and high-sensitivity C-reactive protein level were much lower, and superoxide dismutase level as well as the number of CD4 + CD25 + regulation T cells (Treg) and CD4 + CD25 + CD127-Treg were much higher (P<0.05 or P<0.01) in the treatment group than those in the NC group.ConclusionRA patients with pathologic changes in joints also suffer from lower cardiac and pulmonary functions and from parameters of anemia and platelet factors. XFC can improve the symptoms of RA patients, ameliorate their cardiac and pulmonary functions and reduce the parameters of anemia and platelet factors. XFC lowers the immune inflammatory reaction to improve APCs in RA patients

Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30

SMN (Survival motor neuron protein) was characterized as a dimethyl-arginine binding protein over ten years ago. TDRD3 (Tudor domain-containing protein 3) and SPF30 (Splicing factor 30 kDa) were found to bind to various methyl-arginine proteins including Sm proteins as well later on. Recently, TDRD3 was shown to be a transcriptional coactivator, and its transcriptional activity is dependent on its ability to bind arginine-methylated histone marks. In this study, we systematically characterized the binding specificity and affinity of the Tudor domains of these three proteins quantitatively. Our results show that TDRD3 preferentially recognizes asymmetrical dimethylated arginine mark, and SMN is a very promiscuous effector molecule, which recognizes different arginine containing sequence motifs and preferentially binds symmetrical dimethylated arginine. SPF30 is the weakest methyl-arginine binder, which only binds the GAR motif sequences in our library. In addition, we also reported high-resolution crystal structures of the Tudor domain of TDRD3 in complex with two small molecules, which occupy the aromatic cage of TDRD3

Sep. Purif. Technol.

The flocculation of fine diaspore, kaolinite, illite and pyrophyllite and their artificial mixed minerals and bauxite ore were systematically investigated by the sedimentation tests. The mechanism analyses were performed in combination with examinations through X-ray diffraction (XRD), digital metallographic microscope and infrared spectra. Experimental results showed that the concentrate with A/S (mass ratio of Al(2)O(3)/SiO(2)) 8.9 and the recovery of Al(2)O(3) 86.98% were obtained from bauxite ore (A/S 5.68) at pH 9.5-10 by using sodium carbonate 5 kg/t and sodium polyacrylate 7 g/t. Sodium carbonate can act as both pH modifiers and a favorable dispersant for aluminositicates. High performance of sodium polyacrylate on flocculation for diaspore was due to that carboxyl of sodium polyacrylate interacted with active Al sets of diaspore by chemical absorption or formed hydrogen bond via hydroxyl group of macromolecule with surface Al-OH to enhance the sedimentation rate of diaspore. (C) 2007 Elsevier B.V. All rights reserved.The flocculation of fine diaspore, kaolinite, illite and pyrophyllite and their artificial mixed minerals and bauxite ore were systematically investigated by the sedimentation tests. The mechanism analyses were performed in combination with examinations through X-ray diffraction (XRD), digital metallographic microscope and infrared spectra. Experimental results showed that the concentrate with A/S (mass ratio of Al(2)O(3)/SiO(2)) 8.9 and the recovery of Al(2)O(3) 86.98% were obtained from bauxite ore (A/S 5.68) at pH 9.5-10 by using sodium carbonate 5 kg/t and sodium polyacrylate 7 g/t. Sodium carbonate can act as both pH modifiers and a favorable dispersant for aluminositicates. High performance of sodium polyacrylate on flocculation for diaspore was due to that carboxyl of sodium polyacrylate interacted with active Al sets of diaspore by chemical absorption or formed hydrogen bond via hydroxyl group of macromolecule with surface Al-OH to enhance the sedimentation rate of diaspore. (C) 2007 Elsevier B.V. All rights reserved

J. Therm. Spray Technol.

NiCr/(Cr3C2-BaF2 center dot CaF2) coating was fabricated by atmospheric plasma spray technology using clad powder. The coating shows low porosity, high microhardness and bonding strength, and it also exhibits good friction reduction and wear resistance at elevated temperatures up to 800 A degrees C which is due to the formation of a kind of continuous BaF2 center dot CaF2 eutectic lubricating film. The excellent mechanical and tribological properties of the coating are partially attributed to the protection of NiCr layer of the composite powders which can decrease oxidation, decarburization of Cr3C2, and ablation of BaF2 center dot CaF2 eutectic during spray and deposition process.NiCr/(Cr3C2-BaF2 center dot CaF2) coating was fabricated by atmospheric plasma spray technology using clad powder. The coating shows low porosity, high microhardness and bonding strength, and it also exhibits good friction reduction and wear resistance at elevated temperatures up to 800 A degrees C which is due to the formation of a kind of continuous BaF2 center dot CaF2 eutectic lubricating film. The excellent mechanical and tribological properties of the coating are partially attributed to the protection of NiCr layer of the composite powders which can decrease oxidation, decarburization of Cr3C2, and ablation of BaF2 center dot CaF2 eutectic during spray and deposition process

Preparation and characterization of atmospheric plasma-sprayed NiCr/Cr3C2-BaF2 center dot CaF2 composite coating

NiCr alloy-coated BaF2 center dot CaF2 eutectic and Cr3C2 powders were respectively prepared by both pressurized hydrogen reduction and solid state alloying technology. Using this NiCr/Cr3C2-BaF2 center dot CaF2 composite powder, a derived coating was produced by atmospheric plasma spray (APS) technology. Microstructures and phase compositions of the powders, as well as the deposited coating, were analyzed by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The friction and wear behavior of the coatings from ambient temperature to 800 degrees C was evaluated using a ball-on-disk tribometer. The results show that the NiCr/Cr3C2-BaF2 center dot CaF2 composite coating exhibited low porosity, high microhardness and high cohesive strength, which result in good friction reduction and excellent anti-wear ability at elevated temperatures up to 800 degrees C. The friction coefficient of NiCr/Cr3C2-BaF2 center dot CaF2 coating decreases with increasing temperature. The wear rates of both coating and couple balls are significantly lower at temperatures above 500 degrees C than those tested at room temperature. From the investigation of worn surfaces, it was concluded that brittle fracture and delamination were the dominant wear mechanisms of the coatings at low temperature. A transition stage from brittle to plastic state with decreased shear strength was observed for BaF2 center dot CaF2 eutectic at high temperatures, which resulted in the formation of a continuous lubricating layer in the wear track above 500 degrees C The excellent mechanical properties of the coating were partially attributed to the protection of NiCr layer of the composite powders which decreased the oxidation. decarburization and ablation of Cr3C2-BaF2 center dot CaF2 during spraying. (C) 2009 Elsevier B.V. All rights reserved

removalofanionicionsfromsinglematerialsolutionbybauxitetailingsmodifiedwithfecl36h2o

The adsorbabilities of the unmodified and modified bauxite tailings for Cr（Ⅵ）, As（Ⅴ） and F（Ⅰ） ions were investigated. Batch experiments were carried out to determine the removal rate as a function of adsorbent dosage, solution pH value and shaking time. The results show that the maximum removal rates of Cr（Ⅵ）, As（Ⅴ） and F（Ⅰ ） are respectively 99%, 99% and 90% by using the modified bauxite tailings. The isoelectric point of the unmodified bauxite tailings is 3.6, and that of the modified bauxite tailings is 5.0, which shifts to lower pH values in Cr（Ⅵ） solution. This indicates a specific adsorption of the anionic species on the modified bauxite railings. A new band of Cr2O72 appears in the FTIR, showing that Cr（Ⅵ） is adsorbed on the modified bauxite railings in the form of chemistry adsorption. The adsorption data of Cr（Ⅵ） on the modified bauxite tailings are well described by Freundlich model. The investigations of kinetic models show that pseudo-second-order kinetic model provides the best correlation for the experimental data

Adsorption behavior of Pb2+ and Cd2+ ions on bauxite flotation tailings

The adsorption behavior of Pb2+ and Cd2+ ions on bauxite flotation tailings was investigated to demonstrate the adsorptivity of the bauxite flotation tailings. The adsorption percentage of Pb2+ and Cd2+ ions as a function of adsorbent dosage, solution pH value and shaking time were determined by batch experiments. The maximum adsorption percentage of 99.93% for Pb2+ ions and 99.75% for Cd2+ ions were obtained by using bauxite flotation tailings as adsorbent. The methods, such as zeta potentials, specific surface area measurements and the analysis of adsorption kinetics, were introduced to analyze the adsorption mechanisms of the Pb2+ ions on bauxite flotation tailings. The isoelectric point of bauxite flotation tailings shifts from 3.6 to 5.6 in the presence of Pb2+ ions. The specific surface area of bauxite flotation tailings changes from 12.57 to 20.63 m(2)/g after the adsorption of Pb2+ ions. These results indicate that a specific adsorption of the cation species happens on the surface of bauxite flotation tailings. Adsorption data of Pb2+ ions on the surface of bauxite flotation tailings can be well described by Langmuir model, and the pseudo-second-order kinetic model provides the best correlation for the adsorption data of Pb2+ and Cd2+ ions on bauxite flotation tailings