8 research outputs found

    Clinical Characteristics by sex and <i>5HTR2C</i> rs6318 Ser23 C and Cys23 G allele.

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    <p><sup>a</sup> p-value derived from unadjusted linear model;<sup>b</sup> p-value derived from age-adjusted logistic regression model;<sup>c</sup> p-value derived from age-adjusted linear model;<sup> d</sup> p-value was derived from age-adjusted ordinal logistic regression model with number of diseased vessels modeled as an ordinal variable ranging from 0 to 3.<sup></sup> Note. </p

    Kaplan-Meier curves illustrating the risk of death or myocardial infarction for each rs6318 genotype in Women (panel a) and Men (panel b).

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    <p>Using pre-specified contrasts in a Cox regression model adjusted for covariates, differences were statistically significant when comparing: male Ser23 C hemizygotes and female Ser23 C homozygotes to all Cys23 G carriers (p  = .005); male Ser23 C hemizygotes to male Cys23 G hemizygotes (p  = .022), and female Ser23 C homozygotes to female Cys23 G carriers (p  = .024).</p
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