1,229 research outputs found
Status of Women in Atlanta:A Survey of Economic Demographic, and Social Indicators for the 15-County Area
This report provides a detailed overview of economic, demographic and social aspects of women and girls in the metro Atlanta region. FRC Report 15
Olanzapine Attenuates Cue-elicited Craving for Tobacco
Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures in cue-elicited craving for tobacco.
Objective: If mesolimbic dopamine activity is associated with cue-elicited craving for tobacco, a dopamine antagonist should attenuate cueelicited craving for tobacco. Thus, the aim of the present study was to determine whether an atypical antipsychotic (olanzapine, 5 mg) decreased cue-elicited craving for tobacco.
Method: Participants were randomly assigned to 5 days of pretreatment with olanzapine (5 mg; n=31) or were randomly assigned to 5 days of a matching placebo (n=28). Approximately 8 h after the last dose, participants were exposed to a control cue (pencil) followed by exposure to smoking cues. Participants subsequently smoked either nicotine cigarettes or de-nicotinized cigarettes.
Results: Olanzapine attenuated cue-elicited craving for tobacco but did not moderate the subjective effects of smoking.
Discussion: This study represents one of the first investigations of the effect of atypical antipsychotics on cue-elicited craving for tobacco. The results suggest that medications with similar profiles may reduce cue-elicited craving, which in turn, may partially explain recent observations that atypical antipsychotics may reduce substance use
Status of sonic boom methodology and understanding
In January 1988, approximately 60 representatives of industry, academia, government, and the military gathered at NASA-Langley for a 2 day workshop on the state-of-the-art of sonic boom physics, methodology, and understanding. The purpose of the workshop was to assess the sonic boom area, to determine areas where additional sonic boom research is needed, and to establish some strategies and priorities in this sonic boom research. Attendees included many internationally recognized sonic boom experts who had been very active in the Supersonic Transport (SST) and Supersonic Cruise Aircraft Research Programs of the 60's and 70's. Summaries of the assessed state-of-the-art and the research needs in theory, minimization, atmospheric effects during propagation, and human response are given
'I was more “dinkum” than had been anticipated': Noël Coward’s 1940 Tour of Australia, Waving the Wartime Flag for Britain
On the afternoon of November 17 1940, a gay white English thespian 13,000 miles from
home, with a pianist he had engaged at Romano’s nightclub at 2 o’clock that morning before
taking three aspirin and going to bed, faced hundreds of testosterone-soaked Australian
soldiers at the Ingleburn Army Camp south of Sydney.1 After three songs the pianist
staggered off stage, ill, upon which the entertainer, then one of Britain’s most successful
playwrights and actors, and a celebrity throughout the English-speaking world, took off his
jacket and, on his own account, ‘fended for himself
Recommended from our members
End-user assertions in forms/3 : an empirical study
Spreadsheets are arguably the most widely used programming language in use today, yet spreadsheets commonly contain errors. Research shows that regardless of the experience of the end user, an alarming number of spreadsheets contain errors (91% in recent field audits). Most spreadsheets are created by end users with little or no programming experience. Unfortunately, software engineering research has largely ignored these users. In an attempt to reduce this high error rate, our research is aimed at bringing the benefits of software engineering to end users without requiring that they first learn software engineering principles. One mechanism for creating error-free programs is assertions. An assertion is a program property that always holds. It provides a way to attach more of the specification to the program. We have developed an assertion tool for spreadsheet languages that extends Microsoft Excel's validation scheme and includes capabilities such as assertion propagation. This work describes an empirical study done to assess how well end users understand and use the information provided by the assertion tool as they perform maintenance tasks. The study also provides information about end users' testing behavior
- …