Additional file 1: of Validation of two short questionnaires assessing physical activity in colorectal cancer patients

Physical activity, all participants in total and stratified by sex. Physical activity levels based on Norwegian Food Based Dietary Guideline (i.e. moderate intensity physical activity and vigorous intensity physical activity) are presented in minutes per week as both self-reported by NORDIET-FFQ and objectively measured by SenseWear Armband (SWA). (DOCX 18 kb

Additional file 2: of Validation of two short questionnaires assessing physical activity in colorectal cancer patients

Bland-Altman plots depicting the mean differences (NORDIET-FFQ minus SenseWear Armband (SWA)) for physical activity in minutes per week; A. total-moderate intensity physical activity in minutes/week, B. total-vigorous intensity physical activity, minutes/week. The solid line represents the mean, and the dashed lines represent the 1.96 SDs of the observations. Females denoted as ♀ and males denoted as ♂. (TIF 1133 kb

Wheat challenge in self-reported gluten sensitivity: a comparison of scoring methods

<p><b>Background:</b> The condition non-coeliac gluten sensitivity (NCGS) is clinically similar to coeliac disease, but lack objective diagnostic criteria. Symptom relief on gluten-free diet followed by gluten containing food challenge may confirm the condition in clinical settings.</p> <p><b>Aim:</b> To describe the results of an open bread challenge in patients with suspected NCGS, and to compare the results with recently suggested cut-offs for symptom change.</p> <p><b>Material and methods:</b> Fifty-six patients (12 males) self-instituted on gluten-free diet with negative coeliac disease diagnostics were examined for NCGS by an open bread challenge. Symptoms were reported by Gastrointestinal Symptom Rating Scale, IBS-version (GSRS-IBS) and visual analogue scale (VAS). Results were retrospectively compared to the Salerno and Monash cut-offs for symptom change.</p> <p><b>Results:</b> Forty-seven patients were diagnosed with NCGS. Total GSRS-IBS score and overall symptoms by VAS increased significantly in NCGS (<i>p</i> < .001), but not in non-NCGS patients (<i>p</i> < .12 and <i>p</i> = .08, respectively). Total GSRS-IBS challenge score and overall symptoms by VAS were significantly higher in NCGS than in non-NCGS patients (53 vs. 37, <i>p</i> = .004 and 76 vs. 39 mm, <i>p</i> = .02, respectively). Applying the Salerno and Monash cut-offs, 63 and 75% would be classified with NCGS, respectively. According to total GSRS–IBS absolute agreement was lowest between clinician’s diagnosis and Salerno cut-off (63%) and highest between Salerno and Monash cut-offs (88%).</p> <p><b>Conclusion:</b> Clinician diagnosed 85% with NCGS. The proportion of NCGS was lower according to the Salerno and Monash cut-offs. The Salerno cut-off should be the starting point for a common definition of symptom change.</p