32,095 research outputs found
Bringing Stories to Life by Sharing Archival Material
Last summer I researched the experiences of women at Gettysburg College during the pivotal decade 1965-1975 with the support of a college grant, the Koble Fellowship, a ten-week humanities based faculty-mentored research project. I tracked women\u27s experiences at the college during this period and designed a digital scholarship project to share their stories. As a history major and as a feminist, a project about the history of women and their activism on campus nicely complemented by interests. (excerpt
Setting fire to the Square
Submitted to the Boston Theological Institute for Certificate Completion in Religion and Conflict TransformationConsiderations of an historical event are hereafter understood through a Western Judeo Christian
perspective of religious conflict transformation. The book burning that set fire to
square on May 10, 1933, in Berlin was not an isolated phenomenon; rather it bled into the
romance of war. Similar events occurred across Nazi Germany and well before the twentieth
century. This paper addresses the book burning in Berlin’s Opernplatz for its relevance toward
the development of a restorative leadership role in the modern university, the route of
seminarians. Details of the academy show that, while educational initiative was once a resource
for violence, reevaluation of knowledge ethics provides meaningful purpose in the task of
cultural preservation. Literature is the product of great civilizations; and so by conserving the
stories of Jewish authors in light of the Holocaust, we find a theological trauma witness to faith
and destruction. Conflict transformation requires due acknowledgement of responsibility by all
parties. In this case, after the fire extinguished, the responsibility is vested in active memory and
forever questioning what remains for humanit
Turning Points: Women at Gettysburg College from 1965-1975
This poster is a summary of Christina Noto’s summer research. The research focuses on the experiences of Women at Gettysburg College from the Fall of 1964 to the Spring of 1975. While women attended Gettysburg College, they faced discrimination in all aspects of college life-- in the classroom, athletics, activities, their social lives and housing. This poster focuses on the housing discrimination women faced. Women had much stricter housing regulations. For example, women had to sign in and out of their dorms. Women also had mandatory dorm hours (certain times they had to be in their rooms). While some students were frustrated with the College’s policies and some women noticed discrimination; others did not, or were not frustrated by it. As more and more women questioned the way they were treated, particularly with regards to women’s hours, they planned a sleep-in on March 15, 1969 in the Student Union Building (SUB). This event can be viewed as a turning point for women’s rights at Gettysburg College
The Regulatory Roles of the Galactose Permease and Kinase in the Induction Response of the GAL Network in Saccharomyces cerevisiae
The GAL genetic switch of Saccharomyces cerevisiae exhibits an ultrasensitive response to the inducer galactose as well as the "all-or-none" behavior characteristic of many eukaryotic regulatory networks. We have constructed a strain that allows intermediate levels of gene expression from a tunable GAL1 promoter at both the population and the single cell level by altering the regulation of the galactose permease Gal2p. Similar modifications to other feedback loops regulating the Gal80p repressor and the Gal3p signaling protein did not result in similarly tuned responses, indicating that the level of inducer transport is unique in its ability to control the switch response of the network. In addition, removal of the Gal1p galactokinase from the network resulted in a regimed response due to the dual role of this enzyme in galactose catabolism and transport. These two activities have competing effects on the response of the network to galactose such that the transport effects of Gal1p are dominant at low galactose concentrations, whereas its catabolic effects are dominant at high galactose concentrations. In addition, flow cytometry analysis revealed the unexpected phenomenon of multiple populations in the gal1{Delta} strains, which were not present in the isogenic GAL1 background. This result indicates that Gal1p may play a previously undescribed role in the stability of the GAL network response
The Mechanism of Expansion and the Volatility it created in Three Pheromone Gene Clusters in the Mouse (\u3ci\u3eMus musculus\u3c/i\u3e) Genome
Three families of proteinaceous pheromones have been described in the house mouse: androgen-binding proteins (ABPs), exocrine gland–secreting peptides (ESPs), and major urinary proteins (MUPs), each of which is thought to communicate different information. All three are encoded by large gene clusters in different regions of the mouse genome, clusters that have expanded dramatically during mouse evolutionary history. We report copy number variation among the most recently duplicated Abp genes, which suggests substantial volatility in this gene region. It appears that groups of these genes behave as low copy repeats (LCRs), duplicating as relatively large blocks of genes by nonallelic homologous recombination. An analysis of gene conversion suggested that it did not contribute to the very low or absent divergence among the paralogs duplicated in this way. We evaluated the ESP and MUP gene regions for signs of the LCR pattern but could find no compelling evidence for duplication of gene blocks of any significant size. Assessment of the entire Abp gene region with the Mouse Paralogy Browser supported the conclusion that substantial volatility has occurred there. This was especially evident when comparing strains with all or part of the Mus musculus musculus or Mus musculus castaneus Abp region. No particularly remarkable volatility was observed in the other two gene families, and we discuss the significance of this in light of the various roles proposed for the three families of mouse proteinaceous pheromones
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