510 research outputs found
Effect of inoculation with the arbuscular mycorrhizal fungus Glomus intraradices on the root-knot nematode Meloidogyne incognita in cucumber
Influence of iron fertilization on cadmium uptake by rice seedlings irrigated with cadmium solution
Growth and arsenic uptake by Chinese brake fern inoculated with an arbuscular mycorrhizal fungus
Arbuscular mycorrhizal fungi associated with wild forage plants in typical steppe of eastern Inner Mongolia
Excessive nitrogen inputs in intensive greenhouse cultivation may influence soil microbial biomass and community composition
Occurrence and distribution of arbuscular mycorrhizal fungal species in three types of grassland community of the Tibetan Plateau
On the deflection of asteroids with mirrors
This paper presents an analysis of an asteroid deflection method based on multiple solar concentrators. A model of the deflection through the sublimation of the surface material of an asteroid is presented, with simulation results showing the achievable orbital deflection with, and without, accounting for the effects of mirror contamination due to the ejected debris plume. A second model with simulation results is presented analyzing an enhancement of the Yarkovsky effect, which provides a significant deflection even when the surface temperature is not high enough to sublimate. Finally the dynamical model of solar concentrators in the proximity of an irregular celestial body are discussed, together with a Lyapunov-based controller to maintain the spacecraft concentrators at a required distance from the asteroid
Phase I/II trial of concurrent extracranial palliative radiation therapy with Dabrafenib and Trametinib in metastatic BRAF V600E/K mutation-positive cutaneous Melanoma
Background: Concurrent treatment with BRAF inhibitors and palliative radiation therapy (RT) could be associated with increased toxicity, especially skin toxicity. Current Eastern Cooperative Oncology Group (ECOG) consensus guideline recommend ceasing BRAF inhibitors during RT. There is a lack of data regarding concurrent RT with combined BRAF and MEK inhibitors. This single-arm phase I/II trial was designed to assess the safety and tolerability of palliative RT with concurrent Dabrafenib and Trametinib in patients with BRAF-mutant metastatic melanoma. Materials and methods: Patients received Dabrafenib and Trametinib before and during palliative RT to soft tissue, nodal or bony metastases. The RT dose was escalated stepwise during the study period. Toxicity data including clinical photographs of the irradiated area was collected for up to 12 months following completion of RT. Results: Between June 2016 to October 2019, ten patients were enrolled before the study was stopped early due to low accrual rate. Six patients were treated at level 1 (20 Gy in 5 fractions, any location) and 4 patients at level 2a (30 Gy in 10 fractions with no abdominal viscera exposed). All alive patients completed one year of post-RT follow-up. Of the 82 adverse events (AEs) documented, the majority (90%) were grade 1 and 2. Eight grade 3 events (10%) occurred in five patients, only one was treatment-related (grade 3 fever due to Dabrafenib and Trametinib). No patients experienced grade 3 or 4 RT related toxicities, including skin toxicities. One serious AE was documented in relation to a grade 3 fever due to Dabrafenib and Trametinib requiring hospitalisation. Conclusions: The lack of grade 3 and 4 RT-related toxicities in our study suggests that Dabrafenib and Trametinib may be continued concurrently during fractionated non-visceral palliative RT to extracranial sites
Sequential Decay Distortion of Goldhaber Model Widths for Spectator Fragments
Momentum widths of the primary fragments and observed final fragments have
been investigated within the framework of an Antisymmetrized Molecular Dynamics
transport model code (AMD-V) with a sequential decay afterburner (GEMINI). It
is found that the secondary evaporation effects cause the values of a reduced
momentum width, , derived from momentum widths of the final fragments
to be significantly less than those appropriate to the primary fragment but
close to those observed in many experiments. Therefore, a new interpretation
for experiemental momentum widths of projectile-like fragments is presented.Comment: 4 pages, 3 figs. Accepted for publication in Phys. Rev. C as a Rapid
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