25,316 research outputs found
The concept of social pharmacy
The 13th International Social Pharmacy Workshop will be held in Malta in July 2004. The Social Pharmacy Workshops are international conferences for research in social and behavioural pharmacy. Meetings are held every second year and participation has grown steadily since the first Workshop was held in Helsinki, Finland, in 1980. Following the successful 2002 conference in Sydney, Australia, the 2004 meeting in Malta will be the first one held in the Mediterranean area!peer-reviewe
Frequency Dependent Specific Heat from Thermal Effusion in Spherical Geometry
We present a novel method of measuring the frequency dependent specific heat
at the glass transition applied to 5-polyphenyl-4-ether. The method employs
thermal waves effusing radially out from the surface of a spherical thermistor
that acts as both a heat generator and thermometer. It is a merit of the method
compared to planar effusion methods that the influence of the mechanical
boundary conditions are analytically known. This implies that it is the
longitudinal rather than the isobaric specific heat that is measured. As
another merit the thermal conductivity and specific heat can be found
independently. The method has highest sensitivity at a frequency where the
thermal diffusion length is comparable to the radius of the heat generator.
This limits in practise the frequency range to 2-3 decades. An account of the
3omega-technique used including higher order terms in the temperature
dependency of the thermistor and in the power generated is furthermore given.Comment: 17 pages, 15 figures, Substantially revised versio
Stellar Oscillations Network Group
Stellar Oscillations Network Group (SONG) is an initiative aimed at designing
and building a network of 1m-class telescopes dedicated to asteroseismology and
planet hunting. SONG will have 8 identical telescope nodes each equipped with a
high-resolution spectrograph and an iodine cell for obtaining precision radial
velocities and a CCD camera for guiding and imaging purposes. The main
asteroseismology targets for the network are the brightest (V<6) stars. In
order to improve performance and reduce maintenance costs the instrumentation
will only have very few modes of operation. In this contribution we describe
the motivations for establishing a network, the basic outline of SONG and the
expected performance.Comment: Proc. Vienna Workshop on the Future of Asteroseismology, 20 - 22
September 2006. Comm. in Asteroseismology, Vol. 150, in the pres
The Devil is in the Detail: Hints for Practical Optimisation
Finding the minimum of an objective function, such as a least squares or negative log-likelihood function, with respect to the unknown model parameters is a problem often encountered in econometrics. Consequently, students of econometrics and applied econometricians are usually well-grounded in the broad differences between the numerical procedures employed to solve these problems. Often, however, relatively little time is given to understanding the practical subtleties of implementing these schemes when faced with illbehaved problems. This paper addresses some of the details involved in practical optimisation, such as dealing with constraints on the parameters, specifying starting values, termination criteria and analytical gradients, and illustrates some of the general ideas with several instructive examples.gradient algorithms, unconstrained optimisation, generalised method of moments.
Discrete time-series models when counts are unobservable
Count data in economics have traditionally been modeled by means of integer-valued autoregressive models. Consequently, the estimation of the parameters of these models and their asymptotic properties have been well documented in the literature. The models comprise a description of the survival of counts generally in terms of a binomial thinning process and an independent arrivals process usually specified in terms of a Poisson distribution. This paper extends the existing class of models to encompass situations in which counts are latent and all that is observed is the presence or absence of counts. This is a potentially important modification as many interesting economic phenomena may have a natural interpretation as a series of 'events' that are driven by an underlying count process which is unobserved. Arrivals of the latent counts are modeled either in terms of the Poisson distribution, where multiple counts may arrive in the sampling interval, or in terms of the Bernoulli distribution, where only one new arrival is allowed in the same sampling interval. The models with latent counts are then applied in two practical illustrations, namely, modeling volatility in financial markets as a function of unobservable 'news' and abnormal price spikes in electricity markets being driven by latent 'stress'.Integer-valued autoregression, Poisson distribution, Bernoulli distribution, latent factors, maximum likelihood estimation
Combining in-domain and out-of-domain speech data for automatic recognition of disordered speech
Lattice vibrations and structural instability in Cesium near the cubic to tetragonal transition
Under pressure cesium undergoes a transition from a high-pressure fcc phase
(Cs-II) to a collapsed fcc phase (Cs-III) near 4.2GPa. At 4.4GPa there follows
a transition to the tetragonal Cs-IV phase. In order to investigate the lattice
vibrations in the fcc phase and seek a possible dynamical instability of the
lattice, the phonon spectra of fcc-Cs at volumes near the III-IV transition are
calculated using Savrasov's density functional linear-response LMTO method.
Compared with quasiharmonic model calculations including non-central
interatomic forces up to second neighbours, at the volume (
is the experimental volume of bcc-Cs with =6.048{\AA}), the
linear-response calculations show soft intermediate wavelength
phonons. Similar softening is also observed for
short wavelength and phonons and intermediate
wavelength phonons. The Born-von K\'{a}rm\'{a}n analysis of
dispersion curves indicates that the interplanar force constants exhibit
oscillating behaviours against plane spacing and the large softening of
intermediate wavelength phonons results from a
negative (110)-interplanar force-constant . The frequencies of the
phonons with around 1/3 become imaginary
and the fcc structure becomes dynamically unstable for volumes below .
It is suggested that superstructures corresponding to the
soft mode should be present as a precursor of tetragonal Cs-IV structure.Comment: 12 pages, 5 figure
A Stellar Model-fitting Pipeline for Solar-like Oscillations
Over the past two decades, helioseismology has revolutionized our
understanding of the interior structure and dynamics of the Sun.
Asteroseismology will soon place this knowledge into a broader context by
providing structural data for hundreds of Sun-like stars. Solar-like
oscillations have already been detected from the ground in several stars, and
NASA's Kepler mission is poised to unleash a flood of stellar pulsation data.
Deriving reliable asteroseismic information from these observations demands a
significant improvement in our analysis methods. We report the initial results
of our efforts to develop an objective stellar model-fitting pipeline for
asteroseismic data. The cornerstone of our automated approach is an
optimization method using a parallel genetic algorithm. We describe the details
of the pipeline and we present the initial application to Sun-as-a-star data,
yielding an optimal model that accurately reproduces the known solar
properties.Comment: 5 pages, 2 figs, Stellar Pulsation: Challenges for Theory and
Observation (proceedings to be published by AIP
Galaxy Formation with local photoionisation feedback I. Methods
We present a first study of the effect of local photoionising radiation on
gas cooling in smoothed particle hydrodynamics simulations of galaxy formation.
We explore the combined effect of ionising radiation from young and old stellar
populations. The method computes the effect of multiple radiative sources using
the same tree algorithm used for gravity, so it is computationally efficient
and well resolved. The method foregoes calculating absorption and scattering in
favour of a constant escape fraction for young stars to keep the calculation
efficient enough to simulate the entire evolution of a galaxy in a cosmological
context to the present day. This allows us to quantify the effect of the local
photoionisation feedback through the whole history of a galaxy`s formation. The
simulation of a Milky Way like galaxy using the local photoionisation model
forms ~ 40 % less stars than a simulation that only includes a standard uniform
background UV field. The local photoionisation model decreases star formation
by increasing the cooling time of the gas in the halo and increasing the
equilibrium temperature of dense gas in the disc. Coupling the local radiation
field to gas cooling from the halo provides a preventive feedback mechanism
which keeps the central disc light and produces slowly rising rotation curves
without resorting to extreme feedback mechanisms. These preliminary results
indicate that the effect of local photoionising sources is significant and
should not be ignored in models of galaxy formation.Comment: Accepted for Publication in MNRAS, 13 pages, 13 figure
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