1,942 research outputs found

    Top triangle moose: Combining Higgsless and topcolor mechanisms for mass generation

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    We present the details of a deconstructed model that incorporates both Higgsless and top-color mechanisms. The model alleviates the tension between obtaining the correct top quark mass and keeping Δρ small that exists in many Higgsless models. It does so by singling out the top quark mass generation as arising from a Yukawa coupling to an effective top Higgs which develops a small vacuum expectation value, while electroweak symmetry breaking results largely from a Higgsless mechanism. As a result, the heavy partners of the SM fermions can be light enough to be seen at the LHC. After presenting the model, we detail the phenomenology, showing that for a broad range of masses, these heavy fermions are discoverable at the LHC. © 2009 The American Physical Society

    Auxetic regions in large deformations of periodic frameworks

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    In materials science, auxetic behavior refers to lateral widening upon stretching. We investigate the problem of finding domains of auxeticity in global deformation spaces of periodic frameworks. Case studies include planar periodic mechanisms constructed from quadrilaterals with diagonals as periods and other frameworks with two vertex orbits. We relate several geometric and kinematic descriptions.Comment: Presented at the International Conference on "Interdisciplinary Applications of Kinematics" (IAK18), Lima, Peru, March 201

    Internally coupled ears in living mammals.

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    It is generally held that the right and left middle ears of mammals are acoustically isolated from each other, such that mammals must rely on neural computation to derive sound localisation cues. There are, however, some unusual species in which the middle ear cavities intercommunicate, in which case each ear might be able to act as a pressure-difference receiver. This could improve sound localisation at lower frequencies. The platypus Ornithorhynchus is apparently unique among mammals in that its tympanic cavities are widely open to the pharynx, a morphology resembling that of some non-mammalian tetrapods. The right and left middle ear cavities of certain talpid and golden moles are connected through air passages within the basicranium; one experimental study on Talpa has shown that the middle ears are indeed acoustically coupled by these means. Having a basisphenoid component to the middle ear cavity walls could be an important prerequisite for the development of this form of interaural communication. Little is known about the hearing abilities of platypus, talpid and golden moles, but their audition may well be limited to relatively low frequencies. If so, these mammals could, in principle, benefit from the sound localisation cues available to them through internally coupled ears. Whether or not they actually do remains to be established experimentally.This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s00422-015-0675-

    Is the incidence of meningiomas underestimated? A regional survey

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    We assessed the undercount of meningiomas in a population-based cancer registry. A comprehensive material was formed by compiling hospital sources with the Finnish Cancer Registry database. The completeness of each source ranged 62–69%. The corrected age-standardised meningioma incidence was 2.9/100 000 for men and 13.0/100 000 for women, a third higher than the cancer registry figures

    Probing Colored Particles with Photons, Leptons, and Jets

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    If pairs of new colored particles are produced at the Large Hadron Collider, determining their quantum numbers, and even discovering them, can be non-trivial. We suggest that valuable information can be obtained by measuring the resonant signals of their near-threshold QCD bound states. If the particles are charged, the resulting signatures include photons and leptons and are sufficiently rich for unambiguously determining their various quantum numbers, including the charge, color representation and spin, and obtaining a precise mass measurement. These signals provide well-motivated benchmark models for resonance searches in the dijet, photon+jet, diphoton and dilepton channels. While these measurements require that the lifetime of the new particles be not too short, the resulting limits, unlike those from direct searches for pair production above threshold, do not depend on the particles' decay modes. These limits may be competitive with more direct searches if the particles decay in an obscure way.Comment: 39 pages, 9 figures; v2: more recent searches include

    Pasteurella multocida Heddleston serovar 3 and 4 strains share a common lipopolysaccharide biosynthesis locus but display both inter- and intrastrain lipopolysaccharide heterogeneity

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    Pasteurella multocida is a Gram-negative multispecies pathogen and the causative agent of fowl cholera, a serious disease of poultry which can present in both acute and chronic forms. The major outer membrane component lipopolysaccharide (LPS) is both an important virulence factor and a major immunogen. Our previous studies determined the LPS structures expressed by different P. multocida strains and revealed that a number of strains belonging to different serovars contain the same LPS biosynthesis locus but express different LPS structures due to mutations within glycosyltransferase genes. In this study, we report the full LPS structure of the serovar 4 type strain, P1662, and reveal that it shares the same LPS outer core biosynthesis locus, L3, with the serovar 3 strains P1059 and Pm70. Using directed mutagenesis, the role of each glycosyltransferase gene in LPS outer core assembly was determined. LPS structural analysis of 23 Australian field isolates that contain the L3 locus revealed that at least six different LPS outer core structures can be produced as a result of mutations within the LPS glycosyltransferase genes. Moreover, some field isolates produce multiple but related LPS glycoforms simultaneously, and three LPS outer core structures are remarkably similar to the globo series of vertebrate glycosphingolipids. Our in-depth analysis showing the genetics and full range of P. multocida lipopolysaccharide structures will facilitate the improvement of typing systems and the prediction of the protective efficacy of vaccines

    Pancytopenia due to iron deficiency worsened by iron infusion: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Iron deficiency anemia is commonly associated with thrombocytosis, although thrombocytopenia has been reported in occasional patients with iron-deficiency anemia. Much less common is the development of thrombocytopenia following replenishment of iron stores.</p> <p>Case Presentation</p> <p>We present the unusual case of a 39 year old African American female Jehovah's Witness who presented with a 10 month history of menorrhagia and pancytopenia. Laboratory investigations confirmed a severe iron deficiency. Since blood transfusion was unacceptable to her, she was started on intravenous iron replacement therapy. This precipitated a sudden drop in both her platelet and white blood cell counts. Histopathological examination of the bone marrow revealed a hypercellular marrow with orderly trilineage hematopoiesis, iron deficiency anemia, granulocytic hyperplasia, and mild megakaryocytic hypoplasia. Both her white blood cell and platelet counts recovered uneventfully with continuing iron supplementation. The possible mechanism for this phenomenon is discussed in this report.</p> <p>Conclusion</p> <p>This case illustrates two rather uncommon associations of a very common problem. Severe iron deficiency anemia may be associated with pancytopenia and iron replacement may cause a transient decline in megakaryopoiesis and leukopoiesis. Severe iron deficiency should be added to the list of conditions leading to thrombocytopenia.</p
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