3D tomography of cells in micro-channels

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far been limited to steady specimen, we overcome this restriction and present a method to access the 3D shape of moving objects. The key of our principle is a tilted arrangement of the micro-channel with respect to the focal plane of the microscope. This forces cells to traverse the focal plane in an inclined manner. As a consequence, individual layers of passing cells are recorded which can then be assembled to obtain the volumetric representation. The full 3D information allows for a detailed comparisons with theoretical and numerical predictions unfeasible with e.g.\ 2D imaging. Our technique is exemplified by studying flowing red blood cells in a micro-channel reflecting the conditions prevailing in the microvasculature. We observe two very different types of shapes: `croissants' and `slippers'. Additionally, we perform 3D numerical simulations of our experiment to confirm the observations. Since 3D confocal imaging of cells in flow has not yet been realized, we see high potential in the field of flow cytometry where cell classification thus far mostly relies on 1D scattering and fluorescence signals

Quark confinement and color transparency in a gauge-invariant formulation of QCD

We examine a nonlocal interaction that results from expressing the QCD Hamiltonian entirely in terms of gauge-invariant quark and gluon fields. The interaction couples one quark color-charge density to another, much as electric charge densities are coupled to each other by the Coulomb interaction in QED. In QCD, this nonlocal interaction also couples quark color-charge densities to gluonic color. We show how the leading part of the interaction between quark color-charge densities vanishes when the participating quarks are in a color singlet configuration, and that, for singlet configurations, the residual interaction weakens as the size of a packet of quarks shrinks. Because of this effect, color-singlet packets of quarks should experience final state interactions that increase in strength as these packets expand in size. For the case of an SU(2) model of QCD based on the {\em ansatz} that the gauge-invariant gauge field is a hedgehog configuration, we show how the infinite series that represents the nonlocal interaction between quark color-charge densities can be evaluated nonperturbatively, without expanding it term-by-term. We discuss the implications of this model for QCD with SU(3) color and a gauge-invariant gauge field determined by QCD dynamics.Comment: Revtex, 23 pages; contains additional references with brief comments on sam

Demonstrating the feasibility of standardized application program interfaces that will allow mobile/portable terminals to receive services combining UMTS and DVB-T

Crucial to the commercial exploitation of any service combining UMTS and DVB-T is the availability of standardized API’s adapted to the hybrid UMTS and DVB-T network and to the technical limitations of mobile/portable terminals. This paper describes work carried out in the European Commission Framework Program 5 (FP5) project CONFLUENT to demonstrate the feasibility of such Application Program Interfaces (API’s) by enabling the reception of a Multimedia Home Platform (MHP) based application transmitted over DVB-T on five different terminals with parts of the service running on a mobile phone

Particle Spectrum of the Supersymmetric Standard Model from the Massless Excitations of a Four Dimensional Superstring

A superstring action is quantised with Neveu Schwarz(NS) and Ramond(R) boundary conditions. The zero mass states of the NS sector are classified as the vector gluons, W-mesons, $B_{\mu}$-mesons and scalars containing Higgs. The fifteen zero mass fermions are obtained from the Ramond sector. A space time supersymmetric Hamiltonian of the Standard Model is presented without any conventional SUSY particles

Journalists views and use of social media: Cision Social Journalism Study 2012: global report

The annual Social Journalism Study conducted by Cision and Canterbury Christ Church University, UK, is charting the changes of how journalists and media professionals use social media for work. Unique to this year’s study is the identification of five profile groups of professional social media users who differ in terms of patterns of use, attitude and knowledge.These groups are: Architects, Hunters, Observers, Promoters and Sceptics. This report also includes a Social Journalism Barometer which was developed to assess social media involvement, practice, knowledge and attitudes among journalists and media professionals in different countries. To put journalists in the wider social context of the changing use of technology, we also included a comparison to Forrester’s Social Technographics® framework of general population‘s use of social media

Matched filters for coalescing binaries detection on massively parallel computers

We discuss some computational problems associated to matched filtering of experimental signals from gravitational wave interferometric detectors in a parallel-processing environment. We then specialize our discussion to the use of the APEmille and apeNEXT processors for this task. Finally, we accurately estimate the performance of an APEmille system on a computational load appropriate for the LIGO and VIRGO experiments, and extrapolate our results to apeNEXT.Comment: 19 pages, 6 figure

Softening of First-Order Phase Transition on Quenched Random Gravity Graphs

We perform extensive Monte Carlo simulations of the 10-state Potts model on quenched two-dimensional $\Phi^3$ gravity graphs to study the effect of quenched coordination number randomness on the nature of the phase transition, which is strongly first order on regular lattices. The numerical data provides strong evidence that, due to the quenched randomness, the discontinuous first-order phase transition of the pure model is softened to a continuous transition, representing presumably a new universality class. This result is in striking contrast to a recent Monte Carlo study of the 8-state Potts model on two-dimensional Poissonian random lattices of Voronoi/Delaunay type, where the phase transition clearly stayed of first order, but is in qualitative agreement with results for quenched bond randomness on regular lattices. A precedent for such softening with connectivity disorder is known: in the 10-state Potts model on annealed Phi3 gravity graphs a continuous transition is also observed.Comment: Latex + 5 postscript figures, 10 pages of text, figures appende

Well-posedness and stability results for the Gardner equation

In this article we present local well-posedness results in the classical Sobolev space H^s(R) with s > 1/4 for the Cauchy problem of the Gardner equation, overcoming the problem of the loss of the scaling property of this equation. We also cover the energy space H^1(R) where global well-posedness follows from the conservation laws of the system. Moreover, we construct solitons of the Gardner equation explicitly and prove that, under certain conditions, this family is orbitally stable in the energy space.Comment: 1 figure. Accepted for publication in Nonlin.Diff Eq.and App