Appendix C. The relationship between individual effect sizes (i.e., the log response ratio lnR) and the experiment duration.

The relationship between individual effect sizes (i.e., the log response ratio lnR) and the experiment duration

Cumulus

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  Cumulus was directed by Chris Smith.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

Appendix B. The relationship between the extracted standard deviation and the corresponding extracted means of soil organic carbon.

The relationship between the extracted standard deviation and the corresponding extracted means of soil organic carbon

Additional file 3: Figure S2. of 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D or 3D culture were exposed to AKT inhibitor (MK-2206) or MEK inhibitor (U0126) prior to cell lysis and Western blotting using an antibody that recognizes full length (116kDa) and cleaved (85kDa) forms of PARP, the latter form apparent upon apoptosis. Neither AKT or MAPK inhibition resulted in a significant loss of full length PARP or a corresponding gain in cleaved PARP for either cell line. In contrast, cleaved PARP was seen to increase in response to the apoptosis inducer, camptothecin, included as a positive control. (DOC 59 kb

Additional file 2: Figure S1B. of 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

Process of recovery of cells from 3D culture for experimental analysis. Cells were recovered from the 3D cultures for counting, immunocytochemical analysis or Western blotting as shown using a modification of a previously reported method (Arnold 2001). (DOC 52 kb

SNP dataset

Data for 19,437 SNP loci and 276 individuals in allelic format used for ancestry analyses. Individuals IDs are voucher numbers (see Sampling, genomic and morphological data used for analyses.xlsx for details

Additional file 1: of Mobile Technology for Improved Family Planning (MOTIF): the development of a mobile phone-based (mHealth) intervention to support post-abortion family planning (PAFP) in Cambodia

Supplementary material. (DOC 182 kb

Cumulative Distribution Functions Illustrating Proteome-Wide Trends in Protein Similarity

<p><i>x</i>-axis, bits/aligned position; <i>y</i>-axis, cumulative fraction of HSPs having that number of bits/aligned amino acid pair or less. To facilitate display, only a subset of the 21 possible pair-wise combinations is shown. Data are based upon all reciprocal best BLASTP hits identified in all versus all BLASTP searches of the proteomes. Similarity calculations were restricted to the high-scoring HSP for each BLAST hit, in order to avoid data duplication due to overlapping alignments.</p> <p>There were 13,339 <i>M. musculus–H. sapiens</i> reciprocal best hits; 6,435 between D. melanogaster and <i>A. gambiae;</i> 5,828 between C. intestinalis and <i>H. sapiens;</i> 5,542 between D. melanogaster and <i>H. sapiens;</i> 4,669 between C. elegans and <i>H. sapiens;</i> 4,588 between C. elegans and <i>D. melanogaster;</i> 3,361 between H. sapiens and <i>A. thaliana;</i> and 2,835 between C. elegans and A. thaliana.</p> <p>atha, <i>A. thaliana;</i> cele, <i>C. elegans;</i> cint, <i>C. intestinalis;</i> dmel, <i>D. melanogaster;</i> hsap, <i>H. sapiens;</i> mmus, <i>M. musculus.</i></p

Additional file 1: of The spread of Injectate after ultrasound-guided lateral elbow injection – a cadaveric study

Example of a three-dimensional rendering of injectate distribution, showing no clear pattern or injection pooling or longitudinal injectate spread. (MP4 2766 kb

Intron Lengths Can Be Used as a Molecular Clock

<p><i>y</i>-axis, magnitude of the Spearman correlation coefficient for the five <i>Drosophila</i> distributions shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020015#pcbi-0020015-g008" target="_blank">Figure 8</a>. <i>x</i>-axis, time (millions of years) since last common ancestor based on protein similarities as calculated in [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020015#pcbi-0020015-b030" target="_blank">30</a>]. Black bars above and below each data point denote observed variance in the data and were obtained by randomly resampling 1,000 orthologous intron pairs 100 times. Best-fitting curve (shown in black) y = −0.0057x + 0.9266; R² = 0.9875.</p