18 research outputs found

    An experiment in collaborative writing: day ten

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    We’re starting 2015 with an experiment in collaborative creative writing. What happens when you ask ten academics to write a story together? Taking our cue from the Exquisite Cadaver game played by Surrealist artists and poets in the 1930s, we’ve asked our authors to contribute to a story in progress. We gave them free rein: no restrictions on style or genre. Just file 300 words that continues the story. Marguerite Johnson, a classicist, gamely volunteered to start the experiment, followed by novelist Claire Corbett, creative writing lecturer Donna Hancox and digital cultures researcher Chris Rodley. Our literature columnist Michelle Smith came next, then theatre director Julian Meyrick and creative writing scholars Nike Sulway and Dallas Baker. Chapter nine was from novelist Camilla Nelson and today’s final instalment is from creative writing lecturer Jane Messer

    Mitochondrial-Nuclear DNA Interactions Contribute to the Regulation of Nuclear Transcript Levels as Part of the Inter-Organelle Communication System

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    Nuclear and mitochondrial organelles must maintain a communication system. Loci on the mitochondrial genome were recently reported to interact with nuclear loci. To determine whether this is part of a DNA based communication system we used genome conformation capture to map the global network of DNA-DNA interactions between the mitochondrial and nuclear genomes (Mito-nDNA) in Saccharomyces cerevisiae cells grown under three different metabolic conditions. The interactions that form between mitochondrial and nuclear loci are dependent on the metabolic state of the yeast. Moreover, the frequency of specific mitochondrial - nuclear interactions (i.e. COX1-MSY1 and Q0182-RSM7) showed significant reductions in the absence of mitochondrial encoded reverse transcriptase machinery. Furthermore, these reductions correlated with increases in the transcript levels of the nuclear loci (MSY1 and RSM7). We propose that these interactions represent an inter-organelle DNA mediated communication system and that reverse transcription of mitochondrial RNA plays a role in this process

    FCJ-200 When Memes Go to War: Viral Propaganda in the 2014 Gaza-Israel Conflict

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    During the Gaza-Israel conflict of July-August 2014, a large volume of creative, multimodal digital content aimed at influencing public opinion was disseminated on social media by belligerents and their supporters. This paper highlights two related features of this ‘viral agitprop’: the use of a diverse range of novel, hypermediated forms to represent a limited set of messages, and thematisation of the act of mediation itself. I argue that these practices are a response to the challenges of communicating with multiple publics within data streams that are crowded, competitive and fast-moving. I suggest this content represents a distinctive new Internet genre which problematises accounts of the relationship between war and media by Friedrich Kittler and Jean Baudrillard

    tRNA Gene Identity Affects Nuclear Positioning

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    The three-dimensional organization of genomes is dynamic and plays a critical role in the regulation of cellular development and phenotypes. Here we use proximity-based ligation methods (i.e. chromosome conformation capture [3C] and circularized chromosome confrmation capture [4C]) to explore the spatial organization of tRNA genes and their locusspecific interactions with the ribosomal DNA. Directed replacement of one lysine and two leucine tRNA loci shows that tRNA spatial organization depends on both tRNA coding sequence identity and the surrounding chromosomal loci. These observations support a model whereby the three-dimensional, spatial organization of tRNA loci within the nucleus utilizes tRNA gene-specific signals to affect local interactions, though broader organization of chromosomal regions are determined by factors outside the tRNA genes themselves

    An experiment in collaborative writing

    No full text
    We’re starting 2015 with an experiment in collaborative creative writing. What happens when you ask ten academics to write a story together? Taking our cue from the Exquisite Cadaver game played by Surrealist artists and poets in the 1930s, we’ve asked our authors to contribute to a story in progress. We gave them free rein: no restrictions on style or genre

    An experiment in collaborative writing

    No full text
    We’re starting 2015 with an experiment in collaborative creative writing. What happens when you ask ten academics to write a story together? Taking our cue from the Exquisite Cadaver game played by Surrealist artists and poets in the 1930s, we’ve asked our authors to contribute to a story in progress. We gave them free rein: no restrictions on style or genre
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