522 research outputs found
InterBoxes: A social innovation in education in rural China
Social innovation has increasingly become a hot topic in China, a process in which multiple sectors collaborate with each other, aiming to change the status quo through creative, effective, efficient and sustainable ways. InterBoxes is an innovative project in the form of a social enterprise that commits to improving physical school conditions by building libraries, classrooms, schools and dormitories with refurbished cargo shipping containers called “Boxes”. Within the scope of this project the word “Inter” signifies that each Box is equipped with an Internet connection to the outside world. Conceptually, as a social enterprise, the for-profit, business arm of InterBoxes is projected to operate within metropolitan areas, building structures such as cafés, gyms, bookstores, etc., all which will generate revenue to support the nonprofit operation in rural areas. This descriptive case study examines the implementation and use of InterBoxes as a library in a rural primary school and addresses the promises and challenges facing the project. The findings indicate that InterBoxes demonstrates much potential as a social innovation to improve physical school conditions and other rural education issues through the creative use of space and place. Recommendations for scaling up its operation in connection with a larger global network of innovation using shipping containers are discussed
Review of \u3cem\u3eChinese Americans and the Politics of Race and Culture.\u3c/em\u3e Sucheng Chan and Madeline Y Hsu (Eds). Reviewed by Julian Chun-Chung Chow.
Book review of Sucheng Chan and Madeline Y. Hsu (Eds.), Chinese Americans and the Politics of Race and Culture. Philadelphia, PA: Temple University Press, 2008. $27.95 papercover
\u3cem\u3eMobilizing an Asian American Community.\u3c/em\u3e Linda Trinh Vo.
Book note for Linda Trinh Vo, Mobilizing an Asian American Community. Philadelphia, PA: Temple University Press, 2004. 22.95 papercover
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Welfare Reform and the Delivery of Welfare-to-Work Programs to AAPIs: What Works?
The passage of the Personal Responsibility and Work Opportunity Act (PRWORA) of 1996 has major implications for low-income Asian American and Pacific Islander (AAPI) populations. The purpose of this paper is to provide an overview of the research currently examining the impact of welfare reform on AAPI recipients and the welfare-to-work services available to this population. This article highlights AAPI participation and their timing-out rates in California’s CalWORKs program and their barriers to transitioning to work. Four welfare-to-work program models and recommendations are presented to illustrate strategies that can be used to address the unique needs of AAPI in order to alleviate their high risk for timing-out: one-stop-shops, transitional jobs programs, providing comprehensive and family focused services, and additional research and evaluation of programs specific to assisting the AAPI population on CalWORKs
Spectral filtering of multiple directly modulated channels for WDM access networks by using an FP etalon
[[abstract]]Spectral and waveform reshaping schemes can enhance the transmission distance of fiber links that use directly modulated lasers as transmitters. We prove the feasibility of using a simple Fabry–Perot (FP) etalon as the spectral reshaper for applications in wavelength division multiplexing (WDM) access networks. The transient chirp and adiabatic chirp of a directly modulated laser are analyzed in detail by using the time-resolved chirp measurement. The effects of the original extinction ratio and the adiabatic chirp on the spectral reshaping are clarified to obtain the optimal operation conditions. It is shown that placing a single-cavity FP etalon filter after multiple 10 Gbits/s directly modulated lasers can extend their transmission distances from 10 to 50 km in the 1.55 m wavelength window. Due to the limited filtering capability of the etalon, the choice of the original extinction ratio and finesse of the etalon is discussed in detail from the experiments and simulation.[[incitationindex]]SCI[[incitationindex]]EI[[booktype]]紙本[[booktype]]電子
Implementing Welfare-to-Work Services: A Study of Staff Decision-Making
Copyright 2006 Alliance for Children and FamiliesIn the post-welfare reform era, increased discretion has been given to frontline staff for day-today
welfare policy implementation. To determine how frontline staff address the complex needs
of welfare program participants in this new policy environment, the decision-making processes
of welfare staff (N = 52) in 11 San Francisco Bay Area county social service agencies were assessed
through a case vignette using a Web-based survey design. We examined staff decision making in
four areas: problem recognition, goal formulation, information search processes, and evaluation.
The results suggest that the high level o f staff discretion apparent in the day-to-day implementation
of welfare policy may have important implications for participants. Several recommendations
for policy, practice, and future research are presented
Piperacillin/tazobactam Induced Myelosuppression
Neutropenia, secondary to immune destruction or maturation arrest, is the most commonly described adverse haematological effect of beta-lactam antibiotics. We describe a case of reversible pancytopenia, with evidence of hypocellular marrow, after a prolonged course of piperacillin/tazobactam for 26 days
Hong Kong Chinese school children with elevated urine melamine levels: A prospective follow up study
<p>Abstract</p> <p>Background</p> <p>In 2008, the outbreak of kidney stones in children fed by melamine-tainted milk products in Mainland China has caused major public concern of food safety. We identified Hong Kong school children with elevated urine melamine level from a community-based school survey in 2007-08 and reviewed their clinical status in 2009.</p> <p>Methods</p> <p>In 2007-08, 2119 school children participated in a primary and secondary school survey in Hong Kong using a cluster sampling method. Urine aliquots from 502 subjects were assayed for melamine level. High urine melamine level was defined as urine melamine/creatinine ratio >7.1 μg/mmol. Subjects with high urine melamine level were invited for clinical evaluation in 2009 including urinalysis and ultrasound imaging of the urinary system.</p> <p>Results</p> <p>The age range of this subcohort was 6 - 20 years with 67% girls (335 female and 167 male subjects). The spot urine melamine/creatinine ratio of the 502 urine aliquots ranged from undetectable to 1467 μg/mmol (median 0.8 μg/mmol). Of these, 213 subjects had undetectable level (42%). We invited 47 (9%) subjects with high urine melamine level for re-evaluation and one subject declined. The median duration of follow-up was 23.5 months (interquartile range: 19.8 - 30.6 months). None of the 46 subjects (28% boys, mean age 13.9 ± 2.9 years) had any abnormality detected on ultrasound study of the urinary system. All subjects had stable renal function with a median urine albumin-creatinine ratio of 0.70 mg/mmol (interquartile range: 0.00 - 2.55 mg/mmol).</p> <p>Conclusions</p> <p>Hong Kong Chinese school children with high urine melamine levels appeared to have benign clinical course in the short term although a long term follow-up study is advisable in those with persistently high urine melamine level.</p
Definitive radiotherapy for early stage glottic cancer by 6 MV photons
Purpose: To evaluate the clinical outcome of early glottic cancer (GC) treated by primary radiotherapy (RT) with 6 MV photons. Methods and materials: We retrospectively reviewed the medical records of 695 consecutive patients with T1N0 and T2N0 GC treated between 1983 and 2005 by RT in our institution. Clinical outcome in terms of local control (LC), overall survival (OS) and cause- specific survival (CSS) rate were evaluated. Results: The median follow-up time was 10.5 years.The 10-year actuarial LC rates were as follows: T1A, 91%; T1B, 87%; T2, 77%. The 10-year OS were as follows: T1, 74.2%; T2, 70.7%. The 10-year CSS were as follows: T1, 97.7%; T2, 97.1%. Poorly differentiated histology and tumor biologically effective dose < 65 Gy.© 2012 Tong et al.; licensee BioMed Central Ltd.Link_to_subscribed_fulltex
G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum.
Funder: Hong Kong PhD Fellowship SchemeFunder: Hong Kong Special Administrative Region GovernmentG-quadruplexes are non-helical secondary structures that can fold in vivo in both DNA and RNA. In human cells, they can influence replication, transcription and telomere maintenance in DNA, or translation, transcript processing and stability of RNA. We have previously showed that G-quadruplexes are detectable in the DNA of the malaria parasite Plasmodium falciparum, despite a very highly A/T-biased genome with unusually few guanine-rich sequences. Here, we show that RNA G-quadruplexes can also form in P. falciparum RNA, using rG4-seq for transcriptome-wide structure-specific RNA probing. Many of the motifs, detected here via the rG4seeker pipeline, have non-canonical forms and would not be predicted by standard in silico algorithms. However, in vitro biophysical assays verified formation of non-canonical motifs. The G-quadruplexes in the P. falciparum transcriptome are frequently clustered in certain genes and associated with regions encoding low-complexity peptide repeats. They are overrepresented in particular classes of genes, notably those that encode PfEMP1 virulence factors, stress response genes and DNA binding proteins. In vitro translation experiments and in vivo measures of translation efficiency showed that G-quadruplexes can influence the translation of P. falciparum mRNAs. Thus, the G-quadruplex is a novel player in post-transcriptional regulation of gene expression in this major human pathogen.UK Medical Research Council [grants MR/K000535/1 and MR/L008823/1] to CJM.
Shenzhen Basic Research Project [JCYJ20180507181642811], Research Grants Council of the Hong Kong SAR, China Projects [CityU 11100421, CityU 11101519, CityU 11100218, N_CityU110/17, CityU 21302317], Croucher Foundation [Project No. 9500030, 9509003], State Key Laboratory of Marine Pollution Director Discretionary Fund, City University of Hong Kong [projects 6000711, 7005503, 9667222, 9680261] to CKK.
A generous donation from Mr. and Mrs. Sunny Yang, the University Grants Committee Area of Excellence Scheme (AoE/M-403/16), and the Innovation and Technology Commission, Hong Kong Special Administrative Region Government to the State Key Laboratory of Agrobiotechnology (CUHK) to TFC.
EYCC was supported by the Hong Kong PhD Fellowship Scheme
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