Stock Market Interdependence: Evidence from Australia

This study examines the relationship between Australia’s stock market and the five largest international markets for the period 1991 through 2001. Preliminary findings, using correlation statistics, indicated potential benefits to international diversification for the Australian investor. Further analysis, conducted in the VAR framework using the Johansen co-integration method, found that the Australian market has short and long run linkages with the United States, while tests with other markets found little evidence of interdependence. Moreover, only the US market was found to Grangercause the Australian market.Interdependence, price linkages, internationalisation.

Design and modelling of SOI-based solar thermoelectric generators

In this work, solar micro-thermoelectric generators are designed with a lens concentrating solar radiation onto the membrane of a thermoelectric generator (TEG). By focusing solar radiation, the input heat flux increases; leading to an increase in the temperature gradient across the device. Consequently, a significant improvement in the device efficiency can be achieved. The TEG design involves the use of the SOI wafer's device layer as the first thermoelement and aluminum as the second thermoelement. Isolation trenches are also added to the design for electrical insulation. Heat transfer simulations in COMSOL are performed to verify the viability of the proposed system and an analytical model based on energy balance and heat transfer equations is developed to investigate the performance of solar TEGs with varying geometries, lens parameters, and external conditions. It is found that efficiency is improved by increasing both the concentration factor and the absorptance of the TEG membran

Higgs Boson Production via Gluon Fusion in the Standard Model with four Generations

Higgs bosons can be produced copiously at the LHC via gluon fusion induced by top and bottom quark loops, and can be enhanced strongly if extra heavy quarks exist. We present results for Higgs +zero-, one- and two-jet production at the LHC, in both the Standard Model and the 4th generation model, by evaluating the corresponding heavy quark triangle, box and pentagon Feynman diagrams. We compare the results by using the effective Higgs-gluon interactions in the limit of heavy quarks with the cross sections including the full mass dependences. NLO effects with full mass dependence are included in the inclusive Higgs boson production rate. Our results improve the theoretical basis for fourth generation effects on the Higgs boson search at the LHC.Comment: Published version in PR

BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology.

BindingDB, www.bindingdb.org, is a publicly accessible database of experimental protein-small molecule interaction data. Its collection of over a million data entries derives primarily from scientific articles and, increasingly, US patents. BindingDB provides many ways to browse and search for data of interest, including an advanced search tool, which can cross searches of multiple query types, including text, chemical structure, protein sequence and numerical affinities. The PDB and PubMed provide links to data in BindingDB, and vice versa; and BindingDB provides links to pathway information, the ZINC catalog of available compounds, and other resources. The BindingDB website offers specialized tools that take advantage of its large data collection, including ones to generate hypotheses for the protein targets bound by a bioactive compound, and for the compounds bound by a new protein of known sequence; and virtual compound screening by maximal chemical similarity, binary kernel discrimination, and support vector machine methods. Specialized data sets are also available, such as binding data for hundreds of congeneric series of ligands, drawn from BindingDB and organized for use in validating drug design methods. BindingDB offers several forms of programmatic access, and comes with extensive background material and documentation. Here, we provide the first update of BindingDB since 2007, focusing on new and unique features and highlighting directions of importance to the field as a whole

Nested Hierarchical Dirichlet Processes

We develop a nested hierarchical Dirichlet process (nHDP) for hierarchical topic modeling. The nHDP is a generalization of the nested Chinese restaurant process (nCRP) that allows each word to follow its own path to a topic node according to a document-specific distribution on a shared tree. This alleviates the rigid, single-path formulation of the nCRP, allowing a document to more easily express thematic borrowings as a random effect. We derive a stochastic variational inference algorithm for the model, in addition to a greedy subtree selection method for each document, which allows for efficient inference using massive collections of text documents. We demonstrate our algorithm on 1.8 million documents from The New York Times and 3.3 million documents from Wikipedia.Comment: To appear in IEEE Transactions on Pattern Analysis and Machine Intelligence, Special Issue on Bayesian Nonparametric

Extended flight evaluation of a near-term pitch active control system

Fuel savings can be achieved by moving the center of gravity of an aircraft aft which reduces the static stability margin and consequently the trim drag. However, flying qualities of an aircraft with relaxed static stability can be significantly degraded. The flying qualities can be restored by using a pitch active control system (PACS). This report documents the work accomplished during a follow-on program (see NASA CR-165951 for initial program report) to perform extended flight tests of a near-term PACS. The program included flying qualities analyses, piloted flight simulation tests, aircraft preparation and flight tests to demonstrate that the near-term PACS provided good flying qualities within the linear static stability envelope to a negative 3% static stability margin

The Emergence of Captive Finance Companies and Risk Segmentation of the Consumer Loan Market:Theory and Evidence

A parental seller with market power to some degree in its product market can earn rents. In this context, there is a gain to granting credit for the purchase of the product and thus the establishment of captive finance company for expanding the sales by offering loans to consumers who need financing for purchase of durable good. This paper examines the optimal behavior of such a durable good seller and its captive finance company when the consumer loan market is segmented into captive and independent lending institutions under symmetric and imperfect information on borrower’s creditworthiness. The model presents that one critical difference for captive finance company will be its credit standard. Specifically, the model indicates that captive finance company will follow a more lenient credit standard, leading to the prediction that the likelihood of repayment of a captive loan is lower than that of a bank loan, other things equal. This prediction is tested using unique data sets drawn from a major credit bureau in the U.S. The analysis of credit bureau data shows that a captive automobile loan is less likely to be repaid than a bank automobile loan, which supports the theoretical prediction.Monopolistic Competition, Consumer Loan Market, Captive Finance Company, Differential Loan Performances

Metabolomics on integrated circuit

We have demonstrated a chip-based diagnostics tool for the quantification of metabolites, using specific enzymes, to study enzyme kinetics and calculate the Michaelis-Menten constant. An array of 256×256 ion-sensitive field effect transistors (ISFETs) fabricated in a complementary metal oxide semiconductor (CMOS) process is used for this prototype. We have used hexokinase enzyme reaction on the ISFET CMOS chip with glucose concentration in the physiological range of 0.05 mM – 231 mM and successfully studied the enzyme kinetics of hexokinase in detail. This will promote future research towards multiplexing enzyme-based metabolite quantification on a single chip, ultimately opening a pathway towards a personal metabolome machine