Micro Membrane Filters for Passive Plasma Extraction From Whole Human Blood Using Silicon Nitride-based Microfilters and Plama Collection Using Agarose Gels

AbstractThe novelty of this study resides in the fabrication of a passive, operating on capillary force, penetration-flow microfluidic device for plasma separation, based on both silicon nitride combination (SiN-SiO-SiN)-based microfilters and agarose gels, and its characterization for plasma separation from whole human blood. The fabrication processes are compatible with IC process protocols, with merits of mass productions and precise size control. The fabrication process for silicon nitride membrane was reported at Lab Chip [1], and quantification its applications to affinity-based protein separation on the silicon nitride was reported at MicroTAS’07 [2]. Our method differs from that of group Yobas [3] in the specific separation method and materials, and of group Pizziconi [4] in the geometry of the filter, and fluidic components with the structure

Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow

Article / Letter to editorInstituut Biologie Leide

Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow

Article / Letter to editorInstituut Biologie Leide

Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow

Article / Letter to editorInstituut Biologie Leide

Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow

Article / Letter to editorInstituut Biologie Leide

Discovery of C-glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow

Article / Letter to editorInstituut Biologie Leide

Synergy: easier to say than to prove

Plant science

Honey in traditional Chinese medicine: A guide to future applications of NADES to medicines

Plant science

Nonalcoholic fatty liver disease and the risk of atrial fibrillation stratified by body mass index:a nationwide population-based study

We evaluated the association between nonalcoholic fatty liver disease (NAFLD) and incident atrial fibrillation (AF) and analyzed the impact of NAFLD on AF risk in relation to body mass index (BMI). A total of 8,048,055 subjects without significant liver disease who were available fatty liver index (FLI) values were included. Subjects were categorized into 3 groups based on FLI: 2), higher FLI raised the risk of AF (by 1.6-fold in 30 ≤ FLI 2. The impact of NAFLD on AF risk was accentuated in lean subjects with underweight