1,533 research outputs found

    Deriving social relations among organizational units from process models

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    For companies to sustain competitive advantages, it is required to redesign and improve business processes continuously by monitoring and analyzing process enactment results. Furthermore, organizational structures must be redesigned according to the changes in business processes. However, there are few scientific approaches to redesigning organizational structures. This paper presents a method for deriving and analyzing organizational relations from process models using social network analysis. Process models contain information on who performs which processes or activities, along with the assignment of organizational units such as departments and roles to related activities. To derive social relations among organizational units from process models, three types of metrics are formally defined: transfer of work metrics, subcontracting metrics, and cooperation metrics. By applying these metrics, various relations among organizational units can be derived and analyzed, which can suggest how organizational structure must be redesigned. To verify the method, the proposed metrics are applied to standard process models of the semiconductor and electronic industry in Korea

    A quantum description of bubble growth in a superheated fluid

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    We discuss a quantum description of bubble growth in a superheated liquid Helium by addressing the problem of operator ordering ambiguities that arise due to the presence of position dependent mass (PDM) in this system. Using a supersymmetric quantum mechanics formalism along with the Weyl quantization rule, we are able to identify specific operator orderings for this problem. This is a general method which should be applicable to other PDM systems.Comment: 1 Figure. To be published in Phys. Lett A. v3: Updated abstract and significant changes from v2, in particular inclusion of a new section on Weyl transfor

    Neurologic phenotype of Schimke immuno-osseous dysplasia and neurodevelopmental expression of SMARCAL1

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    Schimke immuno-osseous dysplasia (OMIM 242900) is an uncommon autosomal-recessive multisystem disease caused by mutations in SMARCAL1 (swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1), a gene encoding a putative chromatin remodeling protein. Neurologic manifestations identified to date relate to enhanced atherosclerosis and cerebrovascular disease. Based on a clinical survey, we determined that half of Schimke immuno-osseous dysplasia patients have a small head circumference, and 15% have social, language, motor, or cognitive abnormalities. Postmortem examination of 2 Schimke immuno-osseous dysplasia patients showed low brain weights and subtle brain histologic abnormalities suggestive of perturbed neuron-glial migration such as heterotopia, irregular cortical thickness, incomplete gyral formation, and poor definition of cortical layers. We found that SMARCAL1 is highly expressed in the developing and adult mouse and human brain, including neural precursors and neuronal lineage cells. These observations suggest that SMARCAL1 deficiency may influence brain development and function in addition to its previously recognized effect on cerebral circulation

    Carbon Monoxide Protects against Liver Failure through Nitric Oxide–induced Heme Oxygenase 1

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    Carbon monoxide (CO) and nitric oxide (NO) each have mechanistically unique roles in various inflammatory disorders. Although it is known that CO can induce production of NO and that NO can induce expression of the cytoprotective enzyme heme oxygenase 1 (HO-1), there is no information whether the protective effect of CO ever requires NO production or whether either gas must induce expression of HO-1 to exert its functional effects. Using in vitro and in vivo models of tumor necrosis factor α–induced hepatocyte cell death in mice, we find that activation of nuclear factor κB and increased expression of inducible NO are required for the protective effects of CO, whereas the protective effects of NO require up-regulation of HO-1 expression. When protection from cell death is initiated by CO, NO production and HO-1 activity are each required for the protective effect showing for the first time an essential synergy between these two molecules in tandem providing potent cytoprotection

    Density Fluctuations in Thermal Inflation and Non-Gaussianity

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    We consider primordial fluctuations in thermal inflation scenario. Since the thermal inflation drives about 10 ee-folds after the standard inflation, the time of horizon-exit during inflation corresponding to the present observational scale shifts toward the end of inflation. It generally makes the primordial power spectrum more deviated from a scale-invariant one and hence renders some models inconsistent with observations. We present a mechanism of generating the primordial curvature perturbation at the end of thermal inflation utilizing a fluctuating coupling of a flaton field with the fields in thermal bath. We show that, by adopting the mechanism, some inflation models can be liberated even in the presence of the thermal inflation. We also discuss non-Gaussianity in the mechanism and show that large non-Gaussianity can be generated in this scenario.Comment: 15 pages, 1 figures, minor change

    Local Scale-Dependent Non-Gaussian Curvature Perturbations at Cubic Order

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    We calculate non-Gaussianities in the bispectrum and trispectrum arising from the cubic term in the local expansion of the scalar curvature perturbation. We compute to three-loop order and for general momenta. A procedure for evaluating the leading behavior of the resulting loop-integrals is developed and discussed. Finally, we survey unique non-linear signals which could arise from the cubic term in the squeezed limit. In particular, it is shown that loop corrections can cause fNLsq.f_{NL}^{sq.} to change sign as the momentum scale is varied. There also exists a momentum limit where Ď„NL<0\tau_{NL} <0 can be realized.Comment: Published in JCA

    Dynamics of Entanglement in One-Dimensional Spin Systems

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    We study the dynamics of quantum correlations in a class of exactly solvable Ising-type models. We analyze in particular the time evolution of initial Bell states created in a fully polarized background and on the ground state. We find that the pairwise entanglement propagates with a velocity proportional to the reduced interaction for all the four Bell states. Singlet-like states are favored during the propagation, in the sense that triplet-like states change their character during the propagation under certain circumstances. Characteristic for the anisotropic models is the instantaneous creation of pairwise entanglement from a fully polarized state; furthermore, the propagation of pairwise entanglement is suppressed in favor of a creation of different types of entanglement. The ``entanglement wave'' evolving from a Bell state on the ground state turns out to be very localized in space-time. Further support to a recently formulated conjecture on entanglement sharing is given.Comment: 25 pages, 21 figures; revte

    Theory of output coupling for trapped fermionic atoms

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    We develop a dynamic theory of output coupling, for fermionic atoms initially confined in a magnetic trap. We consider an exactly soluble one-dimensional model, with a spatially localized delta-type coupling between the atoms in the trap and a continuum of free-particle external modes. Two important special cases are considered for the confinement potential: the infinite box and the harmonic oscillator. We establish that in both cases a bound state of the coupled system appears for any value of the coupling constant, implying that the trap population does not vanish in the infinite-time limit. For weak coupling, the energy spectrum of the outgoing beam exhibits peaks corresponding to the initially occupied energy levels in the trap; the height of these peaks increases with the energy. As the coupling gets stronger, the energy spectrum is displaced towards dressed energies of the fermions in the trap. The corresponding dressed states result from the coupling between the unperturbed fermionic states in the trap, mediated by the coupling between these states and the continuum. In the strong-coupling limit, there is a reinforcement of the lowest-energy dressed mode, which contributes to the energy spectrum of the outgoing beam more strongly than the other modes. This effect is especially pronounced for the one-dimensional box, which indicates that the efficiency of the mode-reinforcement mechanism depends on the steepness of the confinement potential. In this case, a quasi-monochromatic anti-bunched atomic beam is obtained. Results for a bosonic sample are also shown for comparison.Comment: 16 pages, 7 figures, added discussion on time-dependent spectral distribution and corresponding figur
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