229 research outputs found

    Pertumbuhan Ekonomi Dan Ketimpangan Antar Kecamatan Di Kabupaten Banyumas, 1993-2000

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    This research attempts to identify the nature of economic growth and to understand disparity among of sub-districts in Banyumas regency. The tools of analysis are Klassen typology, Williamson index, entropy Theil index, trend and Pearson correlation.Klassen typology shows that Banyumas sub-district can be classified into four types: high growth and high income, high income but low growth, high growth but low income, low growth and low income. Based on Williamson index and entropy Theil index, we found that disparity of gross regional domestic product per capita among sub-districts in Banyumas tended to increase over the period of 1993-2000. More importantly, our findings confirmed that Kuznets hypotesis could be found in Banyumas. Indeed, there has been a negative correlation between Williamson index or entropy Theil index with GRDP growth

    Protocadherin-7 contributes to maintenance of bone homeostasis through regulation of osteoclast multinucleation

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    Kim, H., Takegahara, N., Walsh, M. C., Ueda, J., Fujihara, Y., Ikawa, M., & Choi, Y. (2020). Protocadherin-7 contributes to maintenance of bone homeostasis through regulation of osteoclast multinucleation. BMB Reports, 53(9), 472-477. doi:10.5483/BMBRep.2020.53.9.05

    TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

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    AbstractTRAF2 is believed to mediate the activation of NF-κB and JNK induced by the tumor necrosis factor receptor (TNFR) superfamily, which elicits pleiotropic responses in lymphocytes. We have investigated the physiological roles of TRAF2 in these processes by expressing a lymphocyte-specific dominant negative form of TRAF2, thereby blocking this protein's effector function. We find that the TNFR superfamily signals require TRAF2 for activation of JNK but not NF-κB. In addition, we show that TRAF2 induces NF-κB–independent antiapoptotic pathways during TNF-induced apoptosis. Inhibition of TRAF2 leads to splenomegaly, lymphadenopathy, and an increased number of B cells. These findings indicate that TRAF2 is involved in the regulation of lymphocyte function and growth in vivo
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