Higgs phenomenology in the Peccei-Quinn invariant NMSSM

We study the Higgs phenomenology in the Peccei-Quinn invariant NMSSM (PQ-NMSSM) where the low energy mass parameters of the singlet superfield are induced by a spontaneous breakdown of the Peccei-Quinn symmetry. In the generic NMSSM, scalar mixing among CP-even Higgs bosons is constrained by the observed properties of the SM-like Higgs boson, as well as by the LEP bound on the chargino mass and the perturbativity bound on the singlet Yukawa coupling. In the minimal PQ-NMSSM, scalar mixing is further constrained due to the presence of a light singlino-like neutralino. It is noticed that the $2\sigma$ excess of the LEP $Zb\bar b$ events at $m_{b\bar b}\simeq$ 98 GeV can be explained by a singlet-like 98 GeV Higgs boson in the minimal PQ-NMSSM with low $\tan\beta$, stops around or below 1 TeV, and light doublet-higgsinos around the weak scale.Comment: 31 pages, 4 figures; v2: references added, light stop effects discussed, bound on the Higgs invisible decay rate correcte

String theoretic QCD axions in the light of PLANCK and BICEP2

The QCD axion solving the strong CP problem may originate from antisymmetric tensor gauge fields in compactified string theory, with a decay constant around the GUT scale. Such possibility appears to be ruled out now by the detection of tensor modes by BICEP2 and the PLANCK constraints on isocurvature density perturbations. A more interesting and still viable possibility is that the string theoretic QCD axion is charged under an anomalous U(1)A gauge symmetry. In such case, the axion decay constant can be much lower than the GUT scale if moduli are stabilized near the point of vanishing Fayet-Illiopoulos term, and U(1)A-charged matter fields get a vacuum value v ∼ (mSUSYMnPl)1/(n+1) (n ≥ 0) induced by a tachyonic SUSY breaking mass mSUSY. We examine the symmetry breaking pattern of such models during the inflationary epoch with HI ≃ 1014 GeV, and identify the range of the QCD axion decay constant, as well as the corresponding relic axion abundance, consistent with known cosmological constraints. In addition to the case that the PQ symmetry is restored during inflation, i.e. v(tI ) = 0, there are other viable scenarios, including that the PQ symmetry is broken during inflation with v(tI ) ∼ (4HIMnPl)1/(n+1) ∼ 1016–1017 GeV due to the Hubble-induced D-term DA ∼ 82H2 I , while v(t0) ∼ (mSUSYMnPl)1/(n+1) ∼ 109–5×1013 GeV in the present universe, where v(t0) above 1012 GeV requires a fine-tuning of the axion misalignment angle. We also discuss the implications of our results for the size of SUSY breaking soft masses.131211Nsciescopu

Identification of predictive variables for the recurrence of oral mucocele

Oral mucocele is the most common minor salivary gland lesion with good prognosis after surgical removal. However, its recurrence is not rare, sometimes bothersome. This study aimed to identify the possible predictive variables affecting the recurrence rate of oral mucocele. The histoclinical data of 164 patients diagnosed with oral mucocele were retrospectively obtained by reviewing dental records. The predictive variables for its recurrence were identified by analyzing its recurrence rate according to clinical variables. The recurrence rate showed the significant differences according to location and age. Oral mucocele recurred with significantly higher frequency on the ventral mucosa of tongue (50.0%) than on the labial/buccal mucosa (8.8%). Its recurrence was significantly more common in the younger patients (aged 30 years, 4.4%). However, there was no significant difference in recurrence rates between surgical procedures using scalpels and those using lasers. Patients with oral mucocele should be more carefully informed of its possible recurrence, especially when it is found on the ventral surface of the tongue or in a younger population

Solid tumors of the pancreas can put on a mask through cystic change

<p>Abstract</p> <p>Background</p> <p>Solid pancreatic tumors such as pancreatic ductal adenocarcinoma (PDAC), solid pseudopapillary tumor (SPT), and pancreatic endocrine tumor (PET) may occasionally manifest as cystic lesions. In this study, we have put together our accumulated experience with cystic manifestations of various solid tumors of the pancreas.</p> <p>Methods</p> <p>From 2000 to 2006, 376 patients with pancreatic solid tumor resections were reviewed. Ten (2.66%) of these tumors appeared on radiological imaging studies as cystic lesions. We performed a retrospective review of medical records and pathologic findings of these 10 cases.</p> <p>Results</p> <p>Of the ten cases in which solid tumors of the pancreas manifested as cystic lesions, six were PDAC with cystic degeneration, two were SPT undergone complete cystic change, one was cystic PET, and one was a cystic schwannoma. The mean tumor size of the cystic portion in PDAC was 7.3 cm, and three patients were diagnosed as 'pseudocyst' with or without cancer. Two SPT were found incidentally in young women and were diagnosed as other cystic neoplasms. One cystic endocrine tumor was preoperatively suspected as intraductal papillary mucinous neoplasm or mucinous cystic neoplasm.</p> <p>Conclusions</p> <p>Cystic changes of pancreas solid tumors are extremely rare. However, the possibility of cystic manifestation of pancreas solid tumors should be kept in mind.</p

EFFECTS OF PARTICLE SIZE AND FLUIDIZING VELOCITY ON THE CHARGE DENSITY OF ENTRAINED FINES

A previously-developed Faraday cup fluidized bed unit was modified to facilitate the in-situ monitoring of the transient entrainment rate and net charge of entrained fine powders. This enabled the determination of the transient charge density as a function of particle size and residence time of entrained fine particles. The results showed that the charge density increased significantly with increasing size of entrained fines, but was not very sensitive to the residence time and the fluidizing gas velocity for the finest entrained particles at gas velocities of 0.24 and 0.36 m/s. At Ug=0.48 m/s, the charge density of larger particles increased with increasing particle residence time

Light-guiding hydrogels for cell-based sensing and optogenetic synthesis in vivo

Polymer hydrogels are widely used as cell scaffolds for biomedical applications. While the biochemical and biophysical properties of hydrogels have been extensively investigated, little attention has been paid to their potential photonic functionalities. Here, we report cell-integrated polyethylene glycol-based hydrogels for in-vivo optical sensing and therapy applications. Hydrogel patches containing cells were implanted in awake, freely moving mice for several days and shown to offer long-term transparency, biocompatibility, cell-viability, and light-guiding properties (loss: <1 dB/cm). Using optogenetic, glucagon-like peptide-1 (GLP-1) secreting cells, we conducted light-controlled therapy using the hydrogel in a mouse model with type-2 diabetes and attained improved glucose homeostasis. Furthermore, real-time optical readout of encapsulated heat-shock-protein-coupled fluorescent reporter cells made it possible to measure the nanotoxicity of cadmium-based bare and shelled quantum dots (CdTe; CdSe/ZnS) in vivo

Simultaneous fabrication of line defects-embedded periodic lattice by topographically assisted holographic lithography

We have demonstrated simultaneous fabrication of designed defects within a periodic structure. For rapid fabrication of periodic structures incorporating nanoscale line-defects at large area, topographically assisted holographic lithography (TAHL) technique, combining the strength of hologram lithography and phase-shift interference, was proposed. Hot-embossing method generated the photoresist patterns with vertical side walls which enabled phase-shift mask effect at the edge of patterns. Embossing temperature and relief height were crucial parameters for the successful TAHL process. Periodic holes with a diameter of 600 nm at a 1 μm-pitch incorporating 250 nm wide line-defects were obtained simultaneously

Luciferase-Rose Bengal Conjugates for Single Oxygen Generation by Bioluminescence Resonant Energy Transfer

Conjugates of Rose Bengal and Renilla luciferase generated singlet oxygen upon binding with coelenterazine via bioluminescence resonance energy transfer (BRET). Since the applications of conventional PDT have been limited to superficial lesions due to the limited light penetration in tissue, BRET activated PDT which does not require external light illumination may overcome the limitations of conventional PDT.115Ysciescopu

Cultivating Spirulina maxima: Innovative Approaches

This chapter reports an annual production of Spirulina (Arthrospira) maxima in Ansan, South Korea (37.287°N, 126.833°E) with temperate four seasons climate for testing industrial application. Construction on pilot plant of semi-open raceway system (ORS) with each 20 ton culture volume has been established in early 2011 based on building information modeling (BIM). An optimized design of pilot culture system for microalgae scale-up culture in temperate area and details of culture was presented. In scale-up trials using two ORSs, the strain displayed satisfactory annual growth under batch condition. In an annual trial, average biomass concentration was recorded at 0.99 ± 0.16 g/L, which showed stable productivity in a year. Maximum concentration was estimated at 1.418 ± 0.09 g/L in August, while minimum production was estimated at 0.597 ± 0.05 g/L in October. Despite insufficient solar radiation and nutrients, ORS was favorable for S. maxima production. The technical strategies contribute to the annual production of S. maxima in this region: controlling the culture temperature, reducing production cost, and retrospective climatic data-based BIM construction of the greenhouse. Consequently, pilot production of S. maxima was feasible in Korean climates, a region previously thought to be outside its geographic limits